• 7242 Citations
  • 32 h-Index
19992019
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Fingerprint Dive into the research topics where Jeremy Chien is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

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Ovarian Neoplasms Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Down-Regulation Medicine & Life Sciences
Serine Proteases Medicine & Life Sciences
Drug Therapy Medicine & Life Sciences
Mutation Medicine & Life Sciences
Genes Medicine & Life Sciences
Cisplatin Medicine & Life Sciences

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Research Output 1999 2019

Coiled-Coil and C2 Domain-Containing Protein 1A (CC2D1A) Promotes Chemotherapy Resistance in Ovarian Cancer

Kumar, S., Oien, D. B., Khurana, A., Cliby, W., Hartmann, L., Chien, J. & Shridhar, V., Oct 1 2019, In : Frontiers in Oncology. 9, 986.

Research output: Contribution to journalArticle

Open Access
Ovarian Neoplasms
Drug Therapy
Proteins
Recurrence
Platinum

Genome-scale CRISPR knockout screen identifies TIGAR as a modifier of PARP inhibitor sensitivity

Fang, P., De Souza, C., Minn, K. & Chien, J., Dec 1 2019, In : Communications Biology. 2, 1, 335.

Research output: Contribution to journalArticle

Open Access
Clustered Regularly Interspaced Short Palindromic Repeats
NAD ADP-ribosyltransferase
modifiers (genes)
glycolysis
Glycolysis

Heterozygous mutations in valosin-containing protein (VCP) and resistance to VCP inhibitors

Bastola, P., Bilkis, R., De Souza, C., Minn, K. & Chien, J., Dec 1 2019, In : Scientific reports. 9, 1, 11002.

Research output: Contribution to journalArticle

Open Access
Mutation
DNA Sequence Analysis
HCT116 Cells
Frameshift Mutation
Alleles
11 Citations (Scopus)

Therapeutic targeting of PFKFB3 with a novel glycolytic inhibitor PFK158 promotes lipophagy and chemosensitivity in gynecologic cancers

Mondal, S., Roy, D., Sarkar Bhattacharya, S., Jin, L., Jung, D., Zhang, S., Kalogera, E., Staub, J., Wang, Y., Xuyang, W., Khurana, A., Chien, J., Telang, S., Chesney, J., Tapolsky, G., Petras, D. & Shridhar, V., Jan 1 2019, In : International Journal of Cancer. 144, 1, p. 178-189 12 p.

Research output: Contribution to journalArticle

Open Access
Carboplatin
Neoplasms
Paclitaxel
Fluorescent Antibody Technique
Therapeutics
12 Citations (Scopus)

Cisplatin and pemetrexed activate AXL and AXL inhibitor BGB324 enhances mesothelioma cell death from chemotherapy

Oien, D. B., Garay, T., Eckstein, S. & Chien, J., Jan 11 2018, In : Frontiers in Pharmacology. 8, JAN, 970.

Research output: Contribution to journalArticle

Open Access
Pemetrexed
Mesothelioma
Cisplatin
Reactive Oxygen Species
Cell Death