J Nilas Young, MD

Professor

  • 1521 Citations
  • 21 h-Index
1978 …2019
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Research Output 1978 2019

  • 1521 Citations
  • 21 h-Index
  • 83 Article
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Article
2019

Perioperative use of renin-angiotensin system inhibitors and outcomes in patients undergoing cardiac surgery

Ding, Q., Zhang, Z., Liu, H., Nie, H., Berguson, M., Goldhammer, J. E., Young, J. N., Boyd, W. D., Morris, R. & Sun, J., Sep 13 2019, In : Nature communications. 10, 1, 1 p.

Research output: Contribution to journalArticle

Open Access
renin
angiotensins
Angiotensins
Renin-Angiotensin System
Renin
2018
1 Citation (Scopus)

Perioperative aspirin and long-term survival in patients undergoing coronary artery bypass graft

Ding, Q., Liu, H., Zhang, Z., Goldhammer, J., Yuen, E., Li, Z., Yao, L., Young, J. N., Boyd, W. D., Weintraub, W., Morris, R. & Sun, J., Dec 1 2018, In : Scientific Reports. 8, 1, 17051.

Research output: Contribution to journalArticle

Coronary Artery Bypass
Aspirin
Transplants
Survival
Mortality

Response: Postoperative Acute Kidney Injury and Blood Product Transfusion After Synthetic Colloid Use During Cardiac Surgery

Tobey, R., Cheng, H., Gao, M., Li, Z., Young, J. N., Boyd, W. D., Ji, F. & Liu, H., Jan 1 2018, (Accepted/In press) In : Journal of Cardiothoracic and Vascular Anesthesia.

Research output: Contribution to journalArticle

Colloids
Acute Kidney Injury
Blood Transfusion
Thoracic Surgery
2017
7 Citations (Scopus)
Extracorporeal Membrane Oxygenation
Metoprolol
Diltiazem
Emulsions
Glucagon
4 Citations (Scopus)

Postoperative Acute Kidney Injury and Blood Product Transfusion After Synthetic Colloid Use During Cardiac Surgery

Tobey, R., Cheng, H., Gao, M., Li, Z., Young, J. N., Boyd, W. D., Ji, F. & Liu, H., Jun 1 2017, In : Journal of Cardiothoracic and Vascular Anesthesia. 31, 3, p. 853-862 10 p.

Research output: Contribution to journalArticle

Colloids
Acute Kidney Injury
Blood Transfusion
Thoracic Surgery
Starch
8 Citations (Scopus)

Rigid sternal fixation versus modified wire technique for poststernotomy closures: A retrospective cost analysis

Park, J. S., Kuo, J. H., Young, J. N. & Wong, M. S., 2017, In : Annals of Plastic Surgery. 78, 5, p. 537-542 6 p.

Research output: Contribution to journalArticle

Costs and Cost Analysis
Mediastinitis
Medical Errors
Sternotomy
Hospital Costs
2016
19 Citations (Scopus)

Impact of Body Mass Index on Outcomes in Cardiac Surgery

Gao, M., Sun, J., Young, J. N., Boyd, W. D., Atkins, Z., Li, Z., Ding, Q., Diehl, J. & Liu, H., 2016, (Accepted/In press) In : Journal of Cardiothoracic and Vascular Anesthesia.

Research output: Contribution to journalArticle

Thoracic Surgery
Body Mass Index
Thinness
Mortality
Atrial Flutter
12 Citations (Scopus)

Molecular Mechanisms and New Treatment Paradigm for Atrial Fibrillation

Sirish, P., Li, N., Timofeyev, V., Zhang, X. D., Wang, L., Yang, J., Lee, K. S. S., Bettaieb, A., Ma, S. M., Lee, J. H., Su, D., Lau, V. C., Myers, R. E., Lieu, D., Lopez, J. E., Young, J. N., Yamoah, E. N., Haj, F., Ripplinger, C. M., Hammock, B. D. & 1 others, Chiamvimonvat, N., May 1 2016, In : Circulation: Arrhythmia and Electrophysiology. 9, 5, e003721.

Research output: Contribution to journalArticle

Epoxide Hydrolases
Atrial Fibrillation
Anti-Arrhythmia Agents
Inflammation
Acids
13 Citations (Scopus)

The Effect of Dexmedetomidine on Outcomes of Cardiac Surgery in Elderly Patients

Cheng, H., Li, Z., Young, J. N., Boyd, W. D., Atkins, Z., Ji, F. & Liu, H., Dec 1 2016, In : Journal of Cardiothoracic and Vascular Anesthesia. 30, 6, p. 1502-1508 7 p.

Research output: Contribution to journalArticle

Dexmedetomidine
Thoracic Surgery
Delirium
Odds Ratio
Confidence Intervals
2015

Aortic Root Enlargement with Ascending-to-Descending Aortic Bypass in Repair of Coarctation

Perry, P. A. & Young, N., Jul 1 2015, In : Journal of Heart Valve Disease. 24, 4, p. 516-518 3 p.

Research output: Contribution to journalArticle

Aortic Coarctation
Aortic Valve
Transplants
8 Citations (Scopus)

Contemporary Outcomes of Coronary Artery Bypass Grafting Among Patients With Insulin-Treated and Non-Insulin-Treated Diabetes

Li, Z., Amsterdam, E. A., Young, J. N., Hoegh, H. & Armstrong, E. J., 2015, (Accepted/In press) In : Annals of Thoracic Surgery.

Research output: Contribution to journalArticle

Coronary Artery Bypass
Insulin
Aortic Valve
Mitral Valve
Logistic Models
18 Citations (Scopus)

Evidence for preoperative aspirin improving major outcomes in patients with chronic kidney disease undergoing cardiac surgery: a cohort study

Yao, L., Young, J. N., Liu, H., Li, Z., Sun, W., Goldhammer, J., Tao, L., He, J., Diehl, J. & Sun, J., Jan 1 2015, In : Annals of Surgery. 261, 1, p. 207-212 6 p.

Research output: Contribution to journalArticle

Chronic Renal Insufficiency
Aspirin
Thoracic Surgery
Cohort Studies
Glomerular Filtration Rate
2014
7 Citations (Scopus)

A stepwise model for delivering medical humanitarian aid requiring complex interventions

Young, J. N., Everett, J., Simsic, J. M., Taggart, N. W., Litwin, S. B., Lusin, N., Hasse, L., Krivoshchekov, E. V., Marcin, J. P., Raff, G. W. & Cetta, F., Dec 1 2014, In : Journal of Thoracic and Cardiovascular Surgery. 148, 6, p. 2480-2489 10 p.

Research output: Contribution to journalArticle

Russia
Developed Countries
Cardiovascular Diseases
Economics
Medicine
14 Citations (Scopus)

Intraoperative conversion from off-pump to on-pump coronary artery bypass is associated with increased 30-day hospital readmission

Li, Z., Amsterdam, E. A., Danielsen, B., Hoegh, H., Young, J. N. & Armstrong, E. J., 2014, In : Annals of Thoracic Surgery. 98, 1, p. 16-22 7 p.

Research output: Contribution to journalArticle

Patient Readmission
Off-Pump Coronary Artery Bypass
Coronary Artery Bypass
Transplants
Cardiopulmonary Bypass
34 Citations (Scopus)

Perioperative dexmedetomidine improves mortality in patients undergoing coronary artery bypass surgery

Ji, F., Li, Z., Young, J. N., Moore, P. G. & Liu, H., 2014, In : Journal of Cardiothoracic and Vascular Anesthesia. 28, 2, p. 267-273 7 p.

Research output: Contribution to journalArticle

Dexmedetomidine
Coronary Artery Bypass
Mortality
Delirium
Odds Ratio

Response: Does Perioperative dexmedetomidine improve mortality after coronary artery bypass surgery?

Ji, F., Li, Z., Young, J. N., Moore, P. G. & Liu, H., Oct 1 2014, In : Journal of Cardiothoracic and Vascular Anesthesia. 28, 5, p. e47-e48

Research output: Contribution to journalArticle

Cardiac Surgical Procedures
Adrenergic alpha-Agonists
Dexmedetomidine
Coronary Artery Bypass
Mortality
2013
4 Citations (Scopus)

Effect of coronary artery disease extent on contemporary outcomes of combined aortic valve replacement and coronary artery bypass graft surgery

Li, Z., Anderson, I., Amsterdam, E. A., Young, J. N., Parker, J. & Armstrong, E. J., Dec 2013, In : Annals of Thoracic Surgery. 96, 6, p. 2075-2082 8 p.

Research output: Contribution to journalArticle

Aortic Valve
Coronary Artery Bypass
Coronary Artery Disease
Transplants
Mortality
1 Citation (Scopus)

Effect of proteasome inhibitor 1 on wound healing: A potential scar prevention therapy

Walker, J. A., Rossini, G., Thompson, M. W., Wenke, J. C., Baer, D., Pompeo, M. Q., Dezfuli, B., Li, C-S., Young, J. N., Wong, M. S., Tarlton, J. F. & Munro, H. S., Feb 2013, In : Wounds. 25, 2, p. 28-33 6 p.

Research output: Contribution to journalArticle

Proteasome Inhibitors
Dimethyl Sulfoxide
Wound Healing
Cicatrix
Internal-External Control
142 Citations (Scopus)

Perioperative dexmedetomidine improves outcomes of cardiac surgery

Ji, F., Li, Z., Nguyen, H., Young, J. N., Shi, P., Fleming, N. & Liu, H., Apr 16 2013, In : Circulation. 127, 15, p. 1576-1584 9 p.

Research output: Contribution to journalArticle

Dexmedetomidine
Thoracic Surgery
Odds Ratio
Confidence Intervals
Delirium
39 Citations (Scopus)

Post-Bypass Dexmedetomidine Use and Postoperative Acute Kidney Injury in Patients Undergoing Cardiac Surgery with Cardiopulmonary Bypass

Ji, F., Li, Z., Young, J. N., Yeranossian, A. & Liu, H., Oct 10 2013, In : PLoS One. 8, 10, e77446.

Research output: Contribution to journalArticle

dexmedetomidine
Dexmedetomidine
Cardiopulmonary Bypass
Acute Kidney Injury
Surgery

Reply to letters: "Preoperative aspirin use and outcomes in cardiac surgery patients: A role of platelet function assessment" and "preoperative aspirin use in cardiac surgery"

Sun, J., Young, J. N., Liu, H., Yao, L., Silvestry, S., Sun, W., Zhao, N. & Diehl, J., Jul 2013, In : Annals of Surgery. 258, 1

Research output: Contribution to journalArticle

Cardiovascular Surgical Procedures
Preoperative Care
Non-Steroidal Anti-Inflammatory Agents
Aspirin
Thoracic Surgery
3 Citations (Scopus)

Response to letters regarding article, perioperative dexmedetomidine improves outcomes of cardiac surgery

Ji, F., Li, Z., Nguyen, H., Young, J. N., Shi, P., Fleming, N. & Liu, H., Oct 15 2013, In : Circulation. 128, 16

Research output: Contribution to journalArticle

Adrenergic alpha-2 Receptor Agonists
Cardiac Surgical Procedures
Dexmedetomidine
Thoracic Surgery
10 Citations (Scopus)

The effects of preoperative renin-angiotensin system inhibitors on outcomes in patients undergoing cardiac surgery

Shi, P., Li, Z., Young, J. N., Ji, F., Wang, Y., Moore, P. G. & Liu, H., Aug 2013, In : Journal of Cardiothoracic and Vascular Anesthesia. 27, 4, p. 703-709 7 p.

Research output: Contribution to journalArticle

Renin-Angiotensin System
Thoracic Surgery
Acute Kidney Injury
Mortality
Risk Reduction Behavior
11 Citations (Scopus)

The joint council on thoracic surgery education coronary artery assessment tool has high interrater reliability

Lee, R., Enter, D., Lou, X., Feins, R. H., Hicks, G. L., Gasparri, M., Takayama, H., Young, J. N., Calhoon, J. H., Crawford, F. A., Mokadam, N. A. & Fann, J. I., Jun 2013, In : Annals of Thoracic Surgery. 95, 6, p. 2064-2070 7 p.

Research output: Contribution to journalArticle

Thoracic Surgery
Coronary Vessels
Joints
Education
Video Recording
2012
9 Citations (Scopus)

Coronary artery bypass operations for elderly patients in California, 2003 to 2008

Li, Z., Amsterdam, E. A., Yeo, K. K., Hoegh, H., Mahendra, G., Boyd, W. D. & Young, J. N., Apr 2012, In : Annals of Thoracic Surgery. 93, 4, p. 1167-1173 7 p.

Research output: Contribution to journalArticle

Coronary Artery Bypass
Mortality
Logistic Models
Off-Pump Coronary Artery Bypass
Odds Ratio
34 Citations (Scopus)

MicroRNA profiling predicts a variance in the proliferative potential of cardiac progenitor cells derived from neonatal and adult murine hearts

Sirish, P., Lopez, J. E., Li, N., Wong, A., Timofeyev, V., Young, J. N., Majdi, M., Li, R. A., Chen, H. S. V. & Chiamvimonvat, N., Jan 2012, In : Journal of Molecular and Cellular Cardiology. 52, 1, p. 264-272 9 p.

Research output: Contribution to journalArticle

MicroRNAs
Stem Cells
Myocardium
Regeneration
Cell Proliferation
55 Citations (Scopus)

Preoperative aspirin use and outcomes in cardiac surgery patients

Cao, L., Young, J. N., Liu, H., Silvestry, S., Sun, W., Zhao, N., Diehl, J. & Sun, J., Feb 2012, In : Annals of Surgery. 255, 2, p. 399-404 6 p.

Research output: Contribution to journalArticle

Aspirin
Thoracic Surgery
Renal Insufficiency
Intensive Care Units
Cerebrovascular Disorders
1 Citation (Scopus)

The impact of preoperative imaging for atypical atrial myxoma locations

Edwdard Hatz, D., Danielson, D., Young, J. N. & Amsterdam, E. A., Aug 2012, In : Clinical Cardiology. 35, 8, p. 490-493 4 p.

Research output: Contribution to journalArticle

Myxoma
Heart Neoplasms
Transesophageal Echocardiography
Heart Atria
Tomography
1 Citation (Scopus)

Unusual effect of an atrial septal aneurysm on venous drainage during cardiopulmonary bypass

Kumar, S. P., Young, J. N. & Liu, H., Jul 2012, In : Annals of Thoracic Surgery. 94, 1

Research output: Contribution to journalArticle

Cardiopulmonary Bypass
Aneurysm
Drainage
Aortic Valve
Coronary Artery Bypass
2011
3 Citations (Scopus)

Complex aortic valve repair following excision of a papillary fibroelastoma

Danielson, D. S., Zheng, D. J., Mayberg, S. C., Raskin, S. & Young, J. N., Mar 2011, In : Journal of Cardiac Surgery. 26, 2, p. 175-177 3 p.

Research output: Contribution to journalArticle

Aortic Valve
DNA Repair
11 Citations (Scopus)

Relation of race, ethnicity and cardiac surgeons to operative mortality rates in primary coronary artery bypass grafting in California

Castellanos, L. R., Li, Z., Yeo, K. K., Young, J. N., Ayanian, J. Z. & Amsterdam, E. A., Jan 2011, In : American Journal of Cardiology. 107, 1, p. 1-5 5 p.

Research output: Contribution to journalArticle

Race Relations
Coronary Artery Bypass
Mortality
Hispanic Americans
African Americans
2010
68 Citations (Scopus)

Cardiac small conductance Ca2+-activated K+ channel subunits form heteromultimers via the coiled-coil domains in the C termini of the channels

Tuteja, D., Rafizadeh, S., Timofeyev, V., Wang, S., Zhang, Z., Li, N., Mateo, R. K., Singapuri, A., Young, J. N., Knowlton, A. A. & Chiamvimonvat, N., Oct 1 2010, In : Circulation Research. 107, 7, p. 851-859 9 p.

Research output: Contribution to journalArticle

Calcium-Activated Potassium Channels
Muscle Cells
Protein Isoforms
Cardiac Myocytes
Action Potentials
28 Citations (Scopus)

Impact of Public Reporting on Access to Coronary Artery Bypass Surgery: The California Outcomes Reporting Program

Li, Z., Carlisle, D. M., Marcin, J. P., Castellanos, L. R., Romano, P. S., Young, J. N. & Amsterdam, E. A., Apr 2010, In : Annals of Thoracic Surgery. 89, 4, p. 1131-1138 8 p.

Research output: Contribution to journalArticle

Coronary Artery Bypass
Transplants
Mortality
Diagnosis-Related Groups
Confidence Intervals
26 Citations (Scopus)

Off-pump bypass surgery and postoperative stroke: California coronary bypass outcomes reporting program

Li, Z., Denton, T., Yeo, K. K., Parker, J. P., White, R. H., Young, J. N. & Amsterdam, E. A., 2010, In : Annals of Thoracic Surgery. 90, 3, p. 753-759 7 p.

Research output: Contribution to journalArticle

Stroke
Coronary Artery Bypass
Confidence Intervals
Logistic Models
Off-Pump Coronary Artery Bypass
2009
18 Citations (Scopus)

Late surgical mitral valve repair after percutaneous repair with the mitraclip® system

Rogers, J. H., Yeo, K. K., Carroll, J. D., Cleveland, J., Reece, T. B., Gillinov, A. M., Rodriguez, L., Whitlow, P., Woo, Y. J., Herrmann, H. C. & Young, J. N., Nov 2009, In : Journal of Cardiac Surgery. 24, 6, p. 677-681 5 p.

Research output: Contribution to journalArticle

Mitral Valve
Surgical Instruments
Equipment and Supplies
Mitral Valve Insufficiency
2008
12 Citations (Scopus)

Fractured inferior vena cava filter strut presenting as a penetrating foreign body in the right ventricle: Report of a case

Kumar, S. P., Mahtabifard, A. & Young, J. N., Jul 2008, In : Journal of Cardiac Surgery. 23, 4, p. 378-381 4 p.

Research output: Contribution to journalArticle

Vena Cava Filters
Foreign Bodies
Heart Ventricles
Chest Pain
Cardiopulmonary Bypass
24 Citations (Scopus)

Off-pump coronary artery bypass graft surgery in California, 2003 to 2005

Li, Z., Yeo, K. K., Parker, J. P., Mahendra, G., Young, J. N. & Amsterdam, E. A., Dec 2008, In : American Heart Journal. 156, 6, p. 1095-1102 8 p.

Research output: Contribution to journalArticle

Off-Pump Coronary Artery Bypass
Coronary Artery Bypass
Cardiopulmonary Bypass
Transplants
Mortality
2007
99 Citations (Scopus)

Molecular coupling of a Ca2+-activated K+ channel to L-type Ca2+ channels via α-actinin2

Lu, L., Zhang, Q., Timofeyev, V., Zhang, Z., Young, J. N., Shin, H. S., Knowlton, A. A. & Chiamvimonvat, N., Jan 2007, In : Circulation Research. 100, 1, p. 112-120 9 p.

Research output: Contribution to journalArticle

Calcium-Activated Potassium Channels
Cytoskeletal Proteins
Ion Channels
Cardiac Myocytes
Membrane Potentials
2006
4 Citations (Scopus)

Implantable cardioverter-defibrillators: a new preventive medical option.

Glatter, K. A., Young, J. N. & McElvany, M. D., Dec 2006, In : Preventive Cardiology. 9, 1

Research output: Contribution to journalArticle

Implantable Defibrillators
Defibrillators
Heart Failure
Cardiac Resynchronization Therapy
Electrophysiology
2005
144 Citations (Scopus)

Differential expression of small-conductance Ca2+-activated K+ channels SK1, SK2, and SK3 in mouse atrial and ventricular myocytes

Tuteja, D., Xu, D., Timofeyev, V., Lu, L., Sharma, D., Zhang, Z., Xu, Y., Nie, L., Vázquez, A. E., Young, J. N., Glatter, K. A. & Chiamvimonvat, N., Dec 2005, In : American Journal of Physiology - Heart and Circulatory Physiology. 289, 6 58-6

Research output: Contribution to journalArticle

Calcium-Activated Potassium Channels
Muscle Cells
Cardiac Myocytes
Protein Isoforms
S 6
3 Citations (Scopus)

Massive recurrent anterior diaphragmatic hernia, coronary artery disease, and valvular heart disease

Huang, M. W. & Young, J. N., Apr 2005, In : Annals of Thoracic Surgery. 79, 4, p. 1417-1419 3 p.

Research output: Contribution to journalArticle

Uterine Prolapse
Heart Valve Diseases
Aortic Valve Stenosis
Case Management
Coronary Artery Disease
2004

Actinomyces meyeri causing tamponade and constrictive pericarditis

Feeney, C., Abdel-Malek, M., Kordestani, R., Lambert, L. & Young, J. N., Jul 2004, In : Infectious Diseases in Clinical Practice. 12, 4, p. 233-235 3 p.

Research output: Contribution to journalArticle

Constrictive Pericarditis
Actinomyces
Pericarditis
Actinomycosis
Left Ventricular Dysfunction

An update on off-pump and minimally invasive cardiac surgery

Young, J. N. & Cohn, L. H., Nov 2004, In : Patient Care. 38, 11, p. 50-57 8 p.

Research output: Contribution to journalArticle

Minimally Invasive Surgical Procedures
Thoracic Surgery
12 Citations (Scopus)

Cardiac Output Monitoring during Off-Pump Coronary Artery Bypass Grafting

Grow, M., Singh, A., Fleming, N., Young, J. N. & Watnik, M., Feb 2004, In : Journal of Cardiothoracic and Vascular Anesthesia. 18, 1, p. 43-46 4 p.

Research output: Contribution to journalArticle

Off-Pump Coronary Artery Bypass
Coronary Artery Bypass
Cardiac Output
Thermodilution
Heart Rate
11 Citations (Scopus)

Reduction of systolic and diastolic dysfunction by retrograde coronary sinus perfusion during off-pump coronary surgery

Castellá, M., Buckberg, G. D., Woo, Y. J., Young, N. & Vinten-Johansen, J., Apr 2004, In : Journal of Thoracic and Cardiovascular Surgery. 127, 4, p. 1018-1025 8 p.

Research output: Contribution to journalArticle

Infusion Pumps
Coronary Sinus
Ischemia
Perfusion
Swine
3 Citations (Scopus)

Septic thrombophlebitis of the coronary sinus with complete recovery after surgical intervention

Jones, D., Amsterdam, E. A. & Young, J. N., Nov 2004, In : Cardiology in Review. 12, 6, p. 325-326 2 p.

Research output: Contribution to journalArticle

Thrombophlebitis
Coronary Sinus
Infection
2003
179 Citations (Scopus)

Molecular identification and functional roles of a Ca(2+)-activated K+ channel in human and mouse hearts.

Xu, Y., Tuteja, D., Zhang, Z., Xu, D., Zhang, Y., Rodriguez, J., Nie, L., Tuxson, H. R., Young, J. N., Glatter, K. A., Vázquez, A. E., Yamoah, E. N. & Chiamvimonvat, N., Dec 5 2003, In : The Journal of biological chemistry. 278, 49, p. 49085-49094 10 p.

Research output: Contribution to journalArticle

Calcium-Activated Potassium Channels
Polymerase chain reaction
Transcription
Cardiac Myocytes
Action Potentials
1999
8 Citations (Scopus)

Multi-dose crystalloid cardioplegia preserves intracellular sodium homeostasis in myocardium

Schepkin, V. D., Choy, I. O., Budinger, T. F., Young, J. N. & Decampli, W. M., Sep 1999, In : Journal of Molecular and Cellular Cardiology. 31, 9, p. 1643-1651 9 p.

Research output: Contribution to journalArticle

Induced Heart Arrest
Myocardium
Homeostasis
Sodium
Ischemia
1998
29 Citations (Scopus)

Sodium TQF NMR and intracellular sodium in isolated crystalloid perfused rat heart

Schepkin, V. D., Choy, I. O., Budinger, T. F., Obayashi, D. Y., Taylor, S. E., DeCampli, W. M., Amartur, S. C. & Young, J. N., Apr 1998, In : Magnetic Resonance in Medicine. 39, 4, p. 557-563 7 p.

Research output: Contribution to journalArticle

Sodium
Growth
Perfusion
Extracellular Space
Ouabain
1997
34 Citations (Scopus)

Antegrade cold blood cardioplegia is not demonstrably advantageous over cold crystalloid cardioplegia in surgery for congenital heart disease

Young, J. N., Choy, I. O., Silva, N. K., Obayashi, D. Y., Barkan, H. E. & Allen, B. S., 1997, In : Journal of Thoracic and Cardiovascular Surgery. 114, 6, p. 1002-1009 8 p.

Research output: Contribution to journalArticle

Induced Heart Arrest
Heart Diseases
Pediatrics
Cardioplegic Solutions
Thoracic Surgery