No photo of Izumi Maezawa

View Scopus Profile

Izumi Maezawa, PhD; PharmD

Associate Adjunct Professor

  • 1964 Citations
  • 24 h-Index
20022019
If you made any changes in Pure, your changes will be visible here soon.

Fingerprint Dive into the research topics where Izumi Maezawa is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 2 Similar Profiles
Alzheimer Disease Medicine & Life Sciences
Amyloid Medicine & Life Sciences
Microglia Medicine & Life Sciences
Rett Syndrome Medicine & Life Sciences
Amyloid beta-Protein Precursor Medicine & Life Sciences
Pyrones Medicine & Life Sciences
Brain Medicine & Life Sciences
Oligomers Chemical Compounds

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2012 2018

Mitochondrial ROS and Microglia in Rett Syndrome

Jin, L. & Maezawa, I.

Project: Research project

The Role of KCa3.1 in Neuroinflammation in Alzheimer Disease

Maezawa, I.

National Institutes of Health

9/30/13 → 6/30/18

Project: Research project

Alzheimer Disease
Microglia
Amyloid
Calcium-Activated Potassium Channels
Organized Financing

Glutamine Transporters SNAT1 and SNAT2 in Rett Syndrome Microglia

Maezawa, I.

National Institutes of Health

7/5/12 → 6/30/14

Project: Research project

Rett Syndrome
Microglia
Glutamine
Methyl-CpG-Binding Protein 2
Epigenomics

Research Output 2002 2019

  • 1964 Citations
  • 24 h-Index
  • 45 Article
  • 2 Chapter
  • 1 Comment/debate

Corrigendum to “Modulation of mitochondrial complex I activity averts cognitive decline in multiple animal models of familial Alzheimer's disease” [EBioMedicine 2 (2015) 294–305] (Modulation of Mitochondrial Complex I Activity Averts Cognitive Decline in Multiple Animal Models of Familial Alzheimer's Disease (2015) 2(4) (294–305), (S2352396415000729), (10.1016/j.ebiom.2015.03.009))

Zhang, L., Zhang, S., Maezawa, I., Trushin, S., Minhas, P., Pinto, M., Jin, L-W., Prasain, K., Nguyen, T. D. T., Yamazaki, Y., Kanekiyo, T., Bu, G., Gateno, B., Chang, K. O., Nath, K. A., Nemutlu, E., Dzeja, P., Pang, Y. P., Hua, D. H. & Trushina, E., Jan 1 2019, In : EBioMedicine.

Research output: Contribution to journal › Comment/debate

Open Access
Brain
Alzheimer Disease
Animals
Animal Models
Modulation
5 Citations (Scopus)

Repurposing the KCa3.1 inhibitor senicapoc for Alzheimer's disease

Jin, L-W., Lucente, J. D., Nguyen, H. M., Singh, V., Singh, L., Chavez, M., Bushong, T., Wulff, H. & Maezawa, I., Apr 1 2019, In : Annals of Clinical and Translational Neurology. 6, 4, p. 723-738 16 p.

Research output: Contribution to journal › Article

Open Access
Alzheimer Disease
Microglia
Long-Term Potentiation
Brain
Phase III Clinical Trials
2 Citations (Scopus)

A bifunctional anti-amyloid blocks oxidative stress and the accumulation of intraneuronal amyloid-beta

Hilt, S., Altman, R., Kálai, T., Maezawa, I., Gong, Q., Wachsmann-Hogiu, S., Jin, L-W. & Voss, J. C., Aug 12 2018, In : Molecules. 23, 8, 2010.

Research output: Contribution to journal › Article

Oxidative stress
Amyloid
Oxidative Stress
Reactive Oxygen Species
oxygen
8 Citations (Scopus)

Defective GABAergic neurotransmission in the nucleus tractus solitarius in Mecp2-null mice, a model of Rett syndrome

Chen, C-Y., Di Lucente, J., Lin, Y. C., Lien, C. C., Rogawski, M. A., Maezawa, I. & Jin, L-W., Jan 1 2018, In : Neurobiology of Disease. 109, p. 25-32 8 p.

Research output: Contribution to journal › Article

Rett Syndrome
Solitary Nucleus
Synaptic Transmission
GABA-A Receptor Agonists
Inhibitory Postsynaptic Potentials
17 Citations (Scopus)

Dysregulated bile acid synthesis and dysbiosis are implicated in Western diet-induced systemic inflammation, microglial activation, and reduced neuroplasticity

Jena, P. K., Sheng, L., Di Lucente, J., Jin, L-W., Maezawa, I. & Wan, Y-J. Y., May 1 2018, In : FASEB Journal. 32, 5, p. 2866-2877 12 p.

Research output: Contribution to journal › Article

Dysbiosis
Neuronal Plasticity
Nutrition
Bile Acids and Salts
Chemical activation