• 1719 Citations
  • 23 h-Index
20022018
If you made any changes in Pure, your changes will be visible here soon.

Fingerprint Fingerprint is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 2 Similar Profiles
Amyloid Medicine & Life Sciences
Microglia Medicine & Life Sciences
Alzheimer Disease Medicine & Life Sciences
Rett Syndrome Medicine & Life Sciences
Amyloid beta-Protein Precursor Medicine & Life Sciences
Pyrones Medicine & Life Sciences
Amyloid beta-Peptides Medicine & Life Sciences
Neurons Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2012 2018

Alzheimer Disease
Microglia
Amyloid
Calcium-Activated Potassium Channels
Organized Financing

Glutamine Transporters SNAT1 and SNAT2 in Rett Syndrome Microglia

Maezawa, I.

National Institutes of Health

7/5/126/30/14

Project: Research projectExploratory/Developmental Grants

Rett Syndrome
Microglia
Glutamine
Methyl-CpG-Binding Protein 2
Epigenomics

Research Output 2002 2018

  • 1719 Citations
  • 23 h-Index
  • 44 Article
  • 2 Chapter

A bifunctional anti-amyloid blocks oxidative stress and the accumulation of intraneuronal amyloid-beta

Hilt, S., Altman, R., Kálai, T., Maezawa, I., Gong, Q., Wachsmann-Hogiu, S., Jin, L-W. & Voss, J. C., Aug 12 2018, In : Molecules. 23, 8, 2010.

Research output: Contribution to journalArticle

Oxidative stress
Amyloid
Oxidative Stress
Reactive Oxygen Species
oxygen
1 Citations

Defective GABAergic neurotransmission in the nucleus tractus solitarius in Mecp2-null mice, a model of Rett syndrome

Chen, C-Y., Di Lucente, J., Lin, Y. C., Lien, C. C., Rogawski, M. A., Maezawa, I. & Jin, L-W., Jan 1 2018, In : Neurobiology of Disease. 109, p. 25-32 8 p.

Research output: Contribution to journalArticle

Rett Syndrome
Solitary Nucleus
Synaptic Transmission
GABA-A Receptor Agonists
Inhibitory Postsynaptic Potentials
4 Citations

Dysregulated bile acid synthesis and dysbiosis are implicated in Western diet-induced systemic inflammation, microglial activation, and reduced neuroplasticity

Jena, P. K., Sheng, L., Di Lucente, J., Jin, L-W., Maezawa, I. & Wan, Y-J. Y., May 1 2018, In : FASEB Journal. 32, 5, p. 2866-2877 12 p.

Research output: Contribution to journalArticle

Dysbiosis
Neuronal Plasticity
Nutrition
Bile Acids and Salts
Chemical activation
4 Citations

K v 1.3 inhibition as a potential microglia-Targeted therapy for Alzheimer's disease: Preclinical proof of concept

Maezawa, I., Nguyen, H. M., Di Lucente, J., Jenkins, D. P., Singh, V., Hilt, S., Kim, K., Rangaraju, S., Levey, A. I., Wulff, H. & Jin, L-W., Feb 1 2018, In : Brain. 141, 2, p. 596-612 17 p.

Research output: Contribution to journalArticle

Microglia
Amyloid
Alzheimer Disease
Therapeutics
Transgenic Mice

The voltage-gated potassium channel Kv1.3 is required for microglial pro-inflammatory activation in vivo

Di Lucente, J., Nguyen, H. M., Wulff, H., Jin, L-W. & Maezawa, I., Sep 1 2018, In : Glia. 66, 9, p. 1881-1895 15 p.

Research output: Contribution to journalArticle

Voltage-Gated Potassium Channels
Microglia
Long-Term Potentiation
Lipopolysaccharides
Injections