Izumi Maezawa, PhD; PharmD

Associate Adjunct Professor

  • 1841 Citations
  • 23 h-Index
20022019
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Fingerprint Dive into the research topics where Izumi Maezawa is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 2 Similar Profiles
Alzheimer Disease Medicine & Life Sciences
Amyloid Medicine & Life Sciences
Microglia Medicine & Life Sciences
Rett Syndrome Medicine & Life Sciences
Amyloid beta-Protein Precursor Medicine & Life Sciences
Pyrones Medicine & Life Sciences
Neurons Medicine & Life Sciences
Brain Medicine & Life Sciences

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Projects 2012 2018

Alzheimer Disease
Microglia
Amyloid
Calcium-Activated Potassium Channels
Organized Financing
Rett Syndrome
Microglia
Glutamine
Methyl-CpG-Binding Protein 2
Epigenomics

Research Output 2002 2019

  • 1841 Citations
  • 23 h-Index
  • 45 Article
  • 2 Chapter
  • 1 Comment/debate

Corrigendum to “Modulation of mitochondrial complex I activity averts cognitive decline in multiple animal models of familial Alzheimer's disease” [EBioMedicine 2 (2015) 294–305] (Modulation of Mitochondrial Complex I Activity Averts Cognitive Decline in Multiple Animal Models of Familial Alzheimer's Disease (2015) 2(4) (294–305), (S2352396415000729), (10.1016/j.ebiom.2015.03.009))

Zhang, L., Zhang, S., Maezawa, I., Trushin, S., Minhas, P., Pinto, M., Jin, L-W., Prasain, K., Nguyen, T. D. T., Yamazaki, Y., Kanekiyo, T., Bu, G., Gateno, B., Chang, K. O., Nath, K. A., Nemutlu, E., Dzeja, P., Pang, Y. P., Hua, D. H. & Trushina, E., Jan 1 2019, In : EBioMedicine.

Research output: Contribution to journalComment/debate

Open Access
Brain
Alzheimer Disease
Animals
Animal Models
Modulation

Repurposing the KCa3.1 inhibitor senicapoc for Alzheimer's disease

Jin, L-W., Lucente, J. D., Nguyen, H. M., Singh, V., Singh, L., Chavez, M., Bushong, T., Wulff, H. & Maezawa, I., Apr 1 2019, In : Annals of Clinical and Translational Neurology. 6, 4, p. 723-738 16 p.

Research output: Contribution to journalArticle

Open Access
Alzheimer Disease
Microglia
Long-Term Potentiation
Brain
Phase III Clinical Trials
1 Citation (Scopus)

A bifunctional anti-amyloid blocks oxidative stress and the accumulation of intraneuronal amyloid-beta

Hilt, S., Altman, R., Kálai, T., Maezawa, I., Gong, Q., Wachsmann-Hogiu, S., Jin, L-W. & Voss, J. C., Aug 12 2018, In : Molecules. 23, 8, 2010.

Research output: Contribution to journalArticle

Oxidative stress
Amyloid
Oxidative Stress
Reactive Oxygen Species
oxygen
3 Citations (Scopus)

Defective GABAergic neurotransmission in the nucleus tractus solitarius in Mecp2-null mice, a model of Rett syndrome

Chen, C-Y., Di Lucente, J., Lin, Y. C., Lien, C. C., Rogawski, M. A., Maezawa, I. & Jin, L-W., Jan 1 2018, In : Neurobiology of Disease. 109, p. 25-32 8 p.

Research output: Contribution to journalArticle

Rett Syndrome
Solitary Nucleus
Synaptic Transmission
GABA-A Receptor Agonists
Inhibitory Postsynaptic Potentials
8 Citations (Scopus)

Dysregulated bile acid synthesis and dysbiosis are implicated in Western diet-induced systemic inflammation, microglial activation, and reduced neuroplasticity

Jena, P. K., Sheng, L., Di Lucente, J., Jin, L-W., Maezawa, I. & Wan, Y-J. Y., May 1 2018, In : FASEB Journal. 32, 5, p. 2866-2877 12 p.

Research output: Contribution to journalArticle

Dysbiosis
Neuronal Plasticity
Nutrition
Bile Acids and Salts
Chemical activation