Projects per year
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- 2 Similar Profiles
Amyloid
Medicine & Life Sciences
Microglia
Medicine & Life Sciences
Alzheimer Disease
Medicine & Life Sciences
Rett Syndrome
Medicine & Life Sciences
Amyloid beta-Protein Precursor
Medicine & Life Sciences
Pyrones
Medicine & Life Sciences
Amyloid beta-Peptides
Medicine & Life Sciences
Neurons
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2012 2018
- 2 Finished
The Role of KCa3.1 in Neuroinflammation in Alzheimer Disease
9/30/13 → 6/30/18
Project: Research project › Research Project
Alzheimer Disease
Microglia
Amyloid
Calcium-Activated Potassium Channels
Organized Financing
Glutamine Transporters SNAT1 and SNAT2 in Rett Syndrome Microglia
7/5/12 → 6/30/14
Project: Research project › Exploratory/Developmental Grants
Rett Syndrome
Microglia
Glutamine
Methyl-CpG-Binding Protein 2
Epigenomics
Research Output 2002 2018
A bifunctional anti-amyloid blocks oxidative stress and the accumulation of intraneuronal amyloid-beta
Hilt, S., Altman, R., Kálai, T., Maezawa, I., Gong, Q., Wachsmann-Hogiu, S., Jin, L-W. & Voss, J. C., Aug 12 2018, In : Molecules. 23, 8, 2010.Research output: Contribution to journal › Article
Oxidative stress
Amyloid
Oxidative Stress
Reactive Oxygen Species
oxygen
Defective GABAergic neurotransmission in the nucleus tractus solitarius in Mecp2-null mice, a model of Rett syndrome
Chen, C-Y., Di Lucente, J., Lin, Y. C., Lien, C. C., Rogawski, M. A., Maezawa, I. & Jin, L-W., Jan 1 2018, In : Neurobiology of Disease. 109, p. 25-32 8 p.Research output: Contribution to journal › Article
Rett Syndrome
Solitary Nucleus
Synaptic Transmission
GABA-A Receptor Agonists
Inhibitory Postsynaptic Potentials
Dysregulated bile acid synthesis and dysbiosis are implicated in Western diet-induced systemic inflammation, microglial activation, and reduced neuroplasticity
Jena, P. K., Sheng, L., Di Lucente, J., Jin, L-W., Maezawa, I. & Wan, Y-J. Y., May 1 2018, In : FASEB Journal. 32, 5, p. 2866-2877 12 p.Research output: Contribution to journal › Article
Dysbiosis
Neuronal Plasticity
Nutrition
Bile Acids and Salts
Chemical activation
K v 1.3 inhibition as a potential microglia-Targeted therapy for Alzheimer's disease: Preclinical proof of concept
Maezawa, I., Nguyen, H. M., Di Lucente, J., Jenkins, D. P., Singh, V., Hilt, S., Kim, K., Rangaraju, S., Levey, A. I., Wulff, H. & Jin, L-W., Feb 1 2018, In : Brain. 141, 2, p. 596-612 17 p.Research output: Contribution to journal › Article
Microglia
Amyloid
Alzheimer Disease
Therapeutics
Transgenic Mice
The voltage-gated potassium channel Kv1.3 is required for microglial pro-inflammatory activation in vivo
Di Lucente, J., Nguyen, H. M., Wulff, H., Jin, L-W. & Maezawa, I., Sep 1 2018, In : Glia. 66, 9, p. 1881-1895 15 p.Research output: Contribution to journal › Article
Voltage-Gated Potassium Channels
Microglia
Long-Term Potentiation
Lipopolysaccharides
Injections