Projects per year
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- 2 Similar Profiles
Alzheimer Disease
Medicine & Life Sciences
Amyloid
Medicine & Life Sciences
Microglia
Medicine & Life Sciences
Rett Syndrome
Medicine & Life Sciences
Amyloid beta-Protein Precursor
Medicine & Life Sciences
Pyrones
Medicine & Life Sciences
Neurons
Medicine & Life Sciences
Brain
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2012 2018
- 2 Finished
The Role of KCa3.1 in Neuroinflammation in Alzheimer Disease
9/30/13 → 6/30/18
Project: Research project
Alzheimer Disease
Microglia
Amyloid
Calcium-Activated Potassium Channels
Organized Financing
Glutamine Transporters SNAT1 and SNAT2 in Rett Syndrome Microglia
7/5/12 → 6/30/14
Project: Research project
Rett Syndrome
Microglia
Glutamine
Methyl-CpG-Binding Protein 2
Epigenomics
Research Output 2002 2019
Corrigendum to “Modulation of mitochondrial complex I activity averts cognitive decline in multiple animal models of familial Alzheimer's disease” [EBioMedicine 2 (2015) 294–305] (Modulation of Mitochondrial Complex I Activity Averts Cognitive Decline in Multiple Animal Models of Familial Alzheimer's Disease (2015) 2(4) (294–305), (S2352396415000729), (10.1016/j.ebiom.2015.03.009))
Zhang, L., Zhang, S., Maezawa, I., Trushin, S., Minhas, P., Pinto, M., Jin, L-W., Prasain, K., Nguyen, T. D. T., Yamazaki, Y., Kanekiyo, T., Bu, G., Gateno, B., Chang, K. O., Nath, K. A., Nemutlu, E., Dzeja, P., Pang, Y. P., Hua, D. H. & Trushina, E., Jan 1 2019, In : EBioMedicine.Research output: Contribution to journal › Comment/debate
Open Access
Brain
Alzheimer Disease
Animals
Animal Models
Modulation
Repurposing the KCa3.1 inhibitor senicapoc for Alzheimer's disease
Jin, L-W., Lucente, J. D., Nguyen, H. M., Singh, V., Singh, L., Chavez, M., Bushong, T., Wulff, H. & Maezawa, I., Apr 1 2019, In : Annals of Clinical and Translational Neurology. 6, 4, p. 723-738 16 p.Research output: Contribution to journal › Article
Open Access
Alzheimer Disease
Microglia
Long-Term Potentiation
Brain
Phase III Clinical Trials
1
Citation
(Scopus)
A bifunctional anti-amyloid blocks oxidative stress and the accumulation of intraneuronal amyloid-beta
Hilt, S., Altman, R., Kálai, T., Maezawa, I., Gong, Q., Wachsmann-Hogiu, S., Jin, L-W. & Voss, J. C., Aug 12 2018, In : Molecules. 23, 8, 2010.Research output: Contribution to journal › Article
Oxidative stress
Amyloid
Oxidative Stress
Reactive Oxygen Species
oxygen
2
Citations
(Scopus)
Defective GABAergic neurotransmission in the nucleus tractus solitarius in Mecp2-null mice, a model of Rett syndrome
Chen, C-Y., Di Lucente, J., Lin, Y. C., Lien, C. C., Rogawski, M. A., Maezawa, I. & Jin, L-W., Jan 1 2018, In : Neurobiology of Disease. 109, p. 25-32 8 p.Research output: Contribution to journal › Article
Rett Syndrome
Solitary Nucleus
Synaptic Transmission
GABA-A Receptor Agonists
Inhibitory Postsynaptic Potentials
7
Citations
(Scopus)
Dysregulated bile acid synthesis and dysbiosis are implicated in Western diet-induced systemic inflammation, microglial activation, and reduced neuroplasticity
Jena, P. K., Sheng, L., Di Lucente, J., Jin, L-W., Maezawa, I. & Wan, Y-J. Y., May 1 2018, In : FASEB Journal. 32, 5, p. 2866-2877 12 p.Research output: Contribution to journal › Article
Dysbiosis
Neuronal Plasticity
Nutrition
Bile Acids and Salts
Chemical activation