• 1775 Citations
  • 23 h-Index
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Projects 2012 2018

Alzheimer Disease
Calcium-Activated Potassium Channels
Organized Financing

Glutamine Transporters SNAT1 and SNAT2 in Rett Syndrome Microglia

Maezawa, I.

National Institutes of Health


Project: Research projectExploratory/Developmental Grants

Rett Syndrome
Methyl-CpG-Binding Protein 2

Research Output 2002 2018

  • 1775 Citations
  • 23 h-Index
  • 44 Article
  • 2 Chapter

A bifunctional anti-amyloid blocks oxidative stress and the accumulation of intraneuronal amyloid-beta

Hilt, S., Altman, R., Kálai, T., Maezawa, I., Gong, Q., Wachsmann-Hogiu, S., Jin, L-W. & Voss, J. C., Aug 12 2018, In : Molecules. 23, 8, 2010.

Research output: Contribution to journalArticle

Oxidative stress
Oxidative Stress
Reactive Oxygen Species
1 Citations

Defective GABAergic neurotransmission in the nucleus tractus solitarius in Mecp2-null mice, a model of Rett syndrome

Chen, C-Y., Di Lucente, J., Lin, Y. C., Lien, C. C., Rogawski, M. A., Maezawa, I. & Jin, L-W., Jan 1 2018, In : Neurobiology of Disease. 109, p. 25-32 8 p.

Research output: Contribution to journalArticle

Rett Syndrome
Solitary Nucleus
Synaptic Transmission
GABA-A Receptor Agonists
Inhibitory Postsynaptic Potentials
6 Citations

Dysregulated bile acid synthesis and dysbiosis are implicated in Western diet-induced systemic inflammation, microglial activation, and reduced neuroplasticity

Jena, P. K., Sheng, L., Di Lucente, J., Jin, L-W., Maezawa, I. & Wan, Y-J. Y., May 1 2018, In : FASEB Journal. 32, 5, p. 2866-2877 12 p.

Research output: Contribution to journalArticle

Neuronal Plasticity
Bile Acids and Salts
Chemical activation
6 Citations

K v 1.3 inhibition as a potential microglia-Targeted therapy for Alzheimer's disease: Preclinical proof of concept

Maezawa, I., Nguyen, H. M., Di Lucente, J., Jenkins, D. P., Singh, V., Hilt, S., Kim, K., Rangaraju, S., Levey, A. I., Wulff, H. & Jin, L-W., Feb 1 2018, In : Brain. 141, 2, p. 596-612 17 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Transgenic Mice
1 Citations

The voltage-gated potassium channel Kv1.3 is required for microglial pro-inflammatory activation in vivo

Di Lucente, J., Nguyen, H. M., Wulff, H., Jin, L-W. & Maezawa, I., Sep 1 2018, In : Glia. 66, 9, p. 1881-1895 15 p.

Research output: Contribution to journalArticle

Voltage-Gated Potassium Channels
Long-Term Potentiation