Hsin-Yi Henry Ho, PhD

Assistant Professor

  • 2766 Citations
  • 17 h-Index
20002019

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

  • 2766 Citations
  • 17 h-Index
  • 30 Article
  • 1 Review article
2019

Agrin-Lrp4-Ror2 signaling regulates adult hippocampal neurogenesis in mice

Zhang, H., Sathyamurthy, A., Liu, F., Li, L., Zhang, L., Dong, Z., Cui, W., Sun, X., Zhao, K., Wang, H., Ho, H. Y. H., Xiong, W. C. & Mei, L., Jul 3 2019, In : eLife. 8

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Genetic interactions between Ror2 and Wnt9a, Ror1 and Wnt9a and Ror2 and Ror1: Phenotypic analysis of the limb skeleton and palate in compound mutants

Weissenböck, M., Latham, R., Nishita, M., Wolff, L. I., Ho, H-Y. H., Minami, Y. & Hartmann, C., Jan 1 2019, In : Genes to Cells.

Research output: Contribution to journalArticle

2 Scopus citations

Oscillatory cortical forces promote three dimensional cell intercalations that shape the murine mandibular arch

Tao, H., Zhu, M., Lau, K., Whitley, O. K. W., Samani, M., Xiao, X., Chen, X. X., Hahn, N. A., Liu, W., Valencia, M., Wu, M., Wang, X., Fenelon, K. D., Pasiliao, C. C., Hu, D., Wu, J., Spring, S., Ferguson, J., Karuna, E. P., Henkelman, R. M. & 7 others, Dunn, A., Huang, H., Ho, H-Y. H., Atit, R., Goyal, S., Sun, Y. & Hopyan, S., Dec 1 2019, In : Nature communications. 10, 1, 1703.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Wnt/PCP signaling contribution to carcinoma collective cell migration and metastasis

VanderVorst, K., Dreyer, C. A., Konopelski, S. E., Lee, H., Ho, H-Y. H. & Carraway, K. L., Apr 15 2019, In : Cancer Research. 79, 8, p. 1719-1729 11 p.

Research output: Contribution to journalReview article

6 Scopus citations
2018

De novo variant in KIF26B is associated with pontocerebellar hypoplasia with infantile spinal muscular atrophy

Wojcik, M. H., Okada, K., Prabhu, S. P., Nowakowski, D. W., Ramsey, K., Balak, C., Rangasamy, S., Brownstein, C. A., Schmitz-Abe, K., Cohen, J. S., Fatemi, A., Shi, J., Grant, E. P., Narayanan, V., Ho, H-Y. H. & Agrawal, P. B., Jan 1 2018, (Accepted/In press) In : American Journal of Medical Genetics, Part A.

Research output: Contribution to journalArticle

2 Scopus citations

Identification of a WNT5A-responsive degradation domain in the kinesin superfamily protein KIF26B

Karuna, E. P., Choi, S. S., Scales, M. K., Hum, J., Cohen, M., Fierro, F. A. & Ho, H-Y. H., Apr 1 2018, In : Genes. 9, 4, 196.

Research output: Contribution to journalArticle

2 Scopus citations
11 Scopus citations
2017

Kinesin superfamily protein kif26b links wnt5a-ror signaling to the control of cell and tissue behaviors in vertebrates

Susman, M. W., Karuna, E. P., Kunz, R. C., Gujral, T. S., Cantú, A. V., Choi, S. S., Jong, B. Y., Okada, K., Scales, M. K., Hum, J., Hu, L. S., Kirschner, M. W., Nishinakamura, R., Yamada, S., Laird, D. J., Jao, L-E., Gygi, S. P., Greenberg, M. E. & Ho, H-Y. H., Sep 8 2017, In : eLife. 6, e26509.

Research output: Contribution to journalArticle

6 Scopus citations

The Ror1 receptor tyrosine kinase plays a critical role in regulating satellite cell proliferation during regeneration of injured muscle

Kamizaki, K., Doi, R., Hayashi, M., Saji, T., Kanagawa, M., Toda, T., Fukada, S. I., Ho, H-Y. H., Greenberg, M. E., Endo, M. & Minami, Y., Sep 22 2017, In : Journal of Biological Chemistry. 292, 38, p. 15939-15951 13 p.

Research output: Contribution to journalArticle

10 Scopus citations
2016

EphB1 and EphB2 intracellular domains regulate the formation of the corpus callosum and anterior commissure

Robichaux, M. A., Chenaux, G., Ho, H-Y. H., Soskis, M. J., Greenberg, M. E., Henkemeyer, M. & Cowan, C. W., Apr 1 2016, In : Developmental Neurobiology. 76, 4, p. 405-420 16 p.

Research output: Contribution to journalArticle

5 Scopus citations

Meiotic onset is reliant on spatial distribution but independent of germ cell number in the mouse ovary

Arora, R., Abby, E., Ross, A. D. J., Cantu, A. V., Kissner, M. D., Castro, V., Ho, H-Y. H., Livera, G. & Laird, D. J., 2016, In : Journal of Cell Science. 129, 13, p. 2493-2499 7 p.

Research output: Contribution to journalArticle

5 Scopus citations

Planar cell polarity signaling in the uterus directs appropriate positioning of the Crypt for Embryo implantation

Yuan, J., Cha, J., Deng, W., Bartos, A., Sun, X., Ho, H-Y. H., Borg, J. P., Yamaguchi, T. P., Yang, Y., Dey, S. K. & Roberts, R. M., Dec 13 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 50, p. E8079-E8088

Research output: Contribution to journalArticle

17 Scopus citations

Unidirectional Eph/ephrin signaling creates a cortical actomyosin differential to drive cell segregation

O'Neill, A. K., Kindberg, A. A., Niethamer, T. K., Larson, A. R., Ho, H-Y. H., Greenberg, M. E. & Bush, J. O., 2016, In : Journal of Cell Biology. 215, 2, p. 217-229 13 p.

Research output: Contribution to journalArticle

13 Scopus citations
2014

Appropriate Crypt Formation in the Uterus for Embryo Homing and Implantation Requires Wnt5a-ROR Signaling

Cha, J., Bartos, A., Park, C., Sun, X., Li, Y., Cha, S. W., Ajima, R., Ho, H-Y. H., Yamaguchi, T. P. & Dey, S. K., Jul 24 2014, In : Cell Reports. 8, 2, p. 382-392 11 p.

Research output: Contribution to journalArticle

61 Scopus citations

EphB receptor forward signaling regulates area-specific reciprocal thalamic and cortical axon pathfinding

Robichaux, M. A., Chenaux, G., Ho, H-Y. H., Soskis, M. J., Dravis, C., Kwan, K. Y., Sestan, N., Greenberg, M. E., Henkemeyer, M. & Cowan, C. W., Feb 11 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 6, p. 2188-2193 6 p.

Research output: Contribution to journalArticle

18 Scopus citations

Vangl1 and Vangl2: Planar cell polarity components with a developing role in cancer

Hatakeyama, J., Wald, J. H., Printsev, I., Ho, H-Y. H. & Carraway, K. L., Oct 1 2014, In : Endocrine-Related Cancer. 21, 5, p. 345-356 12 p.

Research output: Contribution to journalArticle

30 Scopus citations
2013

An autocrine Wnt5a-Ror signaling loop mediates sympathetic target innervation

Ryu, Y. K., Collins, S. E., Ho, H-Y. H., Zhao, H. & Kuruvilla, R., May 1 2013, In : Developmental Biology. 377, 1, p. 79-89 11 p.

Research output: Contribution to journalArticle

19 Scopus citations
2012

A chemical genetic approach reveals distinct EphB signaling mechanisms during brain development

Soskis, M. J., Ho, H-Y. H., Bloodgood, B. L., Robichaux, M. A., Malik, A. N., Ataman, B., Rubin, A. A., Zieg, J., Zhang, C., Shokat, K. M., Sharma, N., Cowan, C. W. & Greenberg, M. E., Dec 2012, In : Nature Neuroscience. 15, 12, p. 1645-1654 10 p.

Research output: Contribution to journalArticle

19 Scopus citations

Wnt5a-Ror-Dishevelled signaling constitutes a core developmental pathway that controls tissue morphogenesis

Ho, H-Y. H., Susman, M. W., Bikoff, J. B., Ryu, Y. K., Jonas, A. M., Hu, L., Kuruvilla, R. & Greenberg, M. E., Mar 13 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 11, p. 4044-4051 8 p.

Research output: Contribution to journalArticle

143 Scopus citations
2010

EphB-mediated degradation of the RhoA GEF Ephexin5 relieves a developmental brake on excitatory synapse formation

Margolis, S. S., Salogiannis, J., Lipton, D. M., Mandel-Brehm, C., Wills, Z. P., Mardinly, A. R., Hu, L., Greer, P. L., Bikoff, J. B., Ho, H-Y. H., Soskis, M. J., Sahin, M. & Greenberg, M. E., Oct 29 2010, In : Cell. 143, 3, p. 442-455 14 p.

Research output: Contribution to journalArticle

143 Scopus citations
2008

Regulation of Motor Neuron Specification by Phosphorylation of Neurogenin 2

Ma, Y. C., Song, M. R., Park, J. P., Ho, H-Y. H., Hu, L., Kurtev, M. V., Zieg, J., Ma, Q., Pfaff, S. L. & Greenberg, M. E., Apr 10 2008, In : Neuron. 58, 1, p. 65-77 13 p.

Research output: Contribution to journalArticle

84 Scopus citations
2006

Brain-Specific Phosphorylation of MeCP2 Regulates Activity-Dependent Bdnf Transcription, Dendritic Growth, and Spine Maturation

Zhou, Z., Hong, E. J., Cohen, S., Zhao, W. N., Ho, H-Y. H., Schmidt, L., Chen, W. G., Lin, Y., Savner, E., Griffith, E. C., Hu, L., Steen, J. A. J., Weitz, C. J. & Greenberg, M. E., Oct 19 2006, In : Neuron. 52, 2, p. 255-269 15 p.

Research output: Contribution to journalArticle

585 Scopus citations

Cdc42 and PI(4,5)P2-induced actin assembly in xenopus egg extracts

Lebensohn, A. M., Ma, L., Ho, H-Y. H. & Kirschner, M. W., 2006, In : Methods in Enzymology. 406, p. 156-173 18 p., 13.

Research output: Contribution to journalArticle

12 Scopus citations

In Vitro reconstitution of Cdc42-mediated actin assembly using purified components

Ho, H-Y. H., Rohatgi, R., Lebensohn, A. M. & Kirschner, M. W., 2006, In : Methods in Enzymology. 406, p. 174-190 17 p., 14.

Research output: Contribution to journalArticle

9 Scopus citations
2005

The NF2 tumor suppressor merlin and the ERM proteins interact with N-WASP and regulate its actin polymerization function

Manchanda, N., Lyubimova, A., Ho, H-Y. H., James, M. F., Gusella, J. F., Ramesh, N., Snapper, S. B. & Ramesh, V., Apr 1 2005, In : Journal of Biological Chemistry. 280, 13, p. 12517-12522 6 p.

Research output: Contribution to journalArticle

43 Scopus citations
2004

Erk/Src phosphorylation of cortactin acts as a switch on-switch off mechanism that controls its ability to activate N-WASP

Martinez-Quiles, N., Ho, H-Y. H., Kirschner, M. W., Ramesh, N. & Geha, R. S., Jun 2004, In : Molecular and Cellular Biology. 24, 12, p. 5269-5280 12 p.

Research output: Contribution to journalArticle

214 Scopus citations

Purification and architecture of the ubiquitous Wave complex

Gautreau, A., Ho, H-Y. H., Li, J., Steen, H., Gygi, S. P. & Kirschner, M. W., Mar 30 2004, In : Proceedings of the National Academy of Sciences of the United States of America. 101, 13, p. 4379-4383 5 p.

Research output: Contribution to journalArticle

160 Scopus citations

Toca-1 mediates Cdc42-dependent actin nucleation by activating the N-WASP-WIP complex

Ho, H-Y. H., Rohatgi, R., Lebensohn, A. M., Le Ma, M., Li, J., Gygi, S. P. & Kirschner, M. W., Jul 23 2004, In : Cell. 118, 2, p. 203-216 14 p.

Research output: Contribution to journalArticle

317 Scopus citations
2001
75 Scopus citations

Nck and Phosphatidylinositol 4,5-Bisphosphate Synergistically Activate Actin Polymerization through the N-WASP-Arp2/3 Pathway

Rohatgi, R., Nollau, P., Ho, H-Y. H., Kirschner, M. W. & Mayer, B. J., Jul 13 2001, In : Journal of Biological Chemistry. 276, 28, p. 26448-26452 5 p.

Research output: Contribution to journalArticle

300 Scopus citations
2000

Mechanism of N-WASP activation by CDC42 and phosphatidylinositol 4,5-bisphosphate

Rohatgi, R., Ho, H-Y. H. & Kirschner, M. W., Sep 18 2000, In : Journal of Cell Biology. 150, 6, p. 1299-1309 11 p.

Research output: Contribution to journalArticle

450 Scopus citations