• 7429 Citations
  • 37 h-Index
1990 …2021
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Fingerprint Dive into the research topics where Hongwu Chen is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 3 Similar Profiles
Prostatic Neoplasms Medicine & Life Sciences
Androgen Receptors Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Cytoplasmic and Nuclear Receptors Medicine & Life Sciences
Androgens Medicine & Life Sciences
Nuclear Receptor Coactivators Medicine & Life Sciences
Breast Neoplasms Medicine & Life Sciences
Chromatin Medicine & Life Sciences

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Projects 2001 2021

Orphan Nuclear Receptors
Prostatic Neoplasms
Androgen Receptors
Neoplasms
Gene Expression
Epigenomics
Neoplasms
Prostatic Neoplasms
Therapeutics
Androgens
Androgen Receptors
Prostatic Neoplasms
Androgens
Hormones
Neoplasms

Research Output 1990 2019

  • 7429 Citations
  • 37 h-Index
  • 68 Article
  • 1 Comment/debate
1 Citation (Scopus)

Discovery and Characterization of XY101, a Potent, Selective, and Orally Bioavailable RORγInverse Agonist for Treatment of Castration-Resistant Prostate Cancer

Zhang, Y., Wu, X., Xue, X., Li, C., Wang, J., Wang, R., Zhang, C., Wang, C., Shi, Y., Zou, L., Li, Q., Huang, Z., Hao, X., Loomes, K., Wu, D., Chen, H., Xu, J. & Xu, Y., May 9 2019, In : Journal of Medicinal Chemistry. 62, 9, p. 4716-4730 15 p.

Research output: Contribution to journalArticle

Castration
Prostatic Neoplasms
Cytoplasmic and Nuclear Receptors
Therapeutic Uses
Growth

Histone methyltransferase NSD2 mediates the survival and invasion of triple-negative breast cancer cells via stimulating ADAM9-EGFR-AKT signaling

Wang, J. J., Zou, J. X., Wang, H., Duan, Z. J., Wang, H. B., Chen, P., Liu, P. Q., Xu, J. Z. & Chen, H., Jan 1 2019, (Accepted/In press) In : Acta Pharmacologica Sinica.

Research output: Contribution to journalArticle

Triple Negative Breast Neoplasms
Survival
Histone-Lysine N-Methyltransferase
Disintegrins
histone methyltransferase

Overexpressed ABCB1 Induces Olaparib-Taxane Cross-Resistance in Advanced Prostate Cancer

Lombard, A. P., Liu, C., Armstrong, C. M., D'Abronzo, L. S., Lou, W., Chen, H., Dall'Era, M., Ghosh, P. M., Evans, C. P. & Gao, A. C., Jul 1 2019, In : Translational Oncology. 12, 7, p. 871-878 8 p.

Research output: Contribution to journalArticle

Open Access
Prostatic Neoplasms
Therapeutics
Poly(ADP-ribose) Polymerases
Castration
docetaxel
4 Citations (Scopus)

Benzoxazinone-containing 3,5-dimethylisoxazole derivatives as BET bromodomain inhibitors for treatment of castration-resistant prostate cancer

Xue, X., Zhang, Y., Wang, C., Zhang, M., Xiang, Q., Wang, J., Wang, A., Li, C., Zhang, C., Zou, L., Wang, R., Wu, S., Lu, Y., Chen, H., Ding, K., Li, G. & Xu, Y., May 25 2018, In : European Journal of Medicinal Chemistry. 152, p. 542-559 18 p.

Research output: Contribution to journalArticle

Benzoxazines
Castration
Prostatic Neoplasms
Derivatives
Proteins
8 Citations (Scopus)

Bioengineered noncoding RNAs selectively change cellular miRNome profiles for cancer therapy

Ho, P. Y., Duan, Z., Batra, N., Jilek, J. L., Tu, M. J., Qiu, J. X., Hu, Z., Wun, T., Lara, P. N., deVere White, R. W., Chen, H. & Yu, A., Jun 1 2018, In : Journal of Pharmacology and Experimental Therapeutics. 365, 3, p. 494-506 13 p.

Research output: Contribution to journalArticle

Untranslated RNA
MicroRNAs
Neoplasms
Bioengineering
Lung