• 7611 Citations
  • 37 h-Index
1990 …2021
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Fingerprint Dive into the research topics where Hongwu Chen is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 2 Similar Profiles
Prostatic Neoplasms Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Androgen Receptors Medicine & Life Sciences
Cytoplasmic and Nuclear Receptors Medicine & Life Sciences
Androgens Medicine & Life Sciences
Nuclear Receptor Coactivators Medicine & Life Sciences
Chromatin Medicine & Life Sciences
Breast Neoplasms Medicine & Life Sciences

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Projects 2001 2021

Orphan Nuclear Receptors
Prostatic Neoplasms
Androgen Receptors
Neoplasms
Gene Expression
Epigenomics
Neoplasms
Prostatic Neoplasms
Therapeutics
Androgens
Androgen Receptors
Prostatic Neoplasms
Androgens
Hormones
Neoplasms

Research Output 1990 2020

  • 7611 Citations
  • 37 h-Index
  • 70 Article
  • 1 Comment/debate

Targeting bromodomain protein ANCCA/ATAD2 enhances the efficacy of DNA-damaging chemotherapy agents and radiation

Duan, Z., Andrews, N. P., Chen, C. Z., Fan, M., Wang, J., Shen, J., Li, J. J. & Chen, H. W., Jan 1 2020, In : Oncology Reports. 43, 1, p. 318-327 10 p.

Research output: Contribution to journalArticle

Protein Transport
DNA Damage
Triple Negative Breast Neoplasms
Radiation
Drug Therapy
6 Citations (Scopus)

Discovery and Characterization of XY101, a Potent, Selective, and Orally Bioavailable RORγInverse Agonist for Treatment of Castration-Resistant Prostate Cancer

Zhang, Y., Wu, X., Xue, X., Li, C., Wang, J., Wang, R., Zhang, C., Wang, C., Shi, Y., Zou, L., Li, Q., Huang, Z., Hao, X., Loomes, K., Wu, D., Chen, H., Xu, J. & Xu, Y., May 9 2019, In : Journal of Medicinal Chemistry. 62, 9, p. 4716-4730 15 p.

Research output: Contribution to journalArticle

Castration
Prostatic Neoplasms
Cytoplasmic and Nuclear Receptors
Therapeutic Uses
Growth
1 Citation (Scopus)

Histone methyltransferase NSD2 mediates the survival and invasion of triple-negative breast cancer cells via stimulating ADAM9-EGFR-AKT signaling

Wang, J. J., Zou, J. X., Wang, H., Duan, Z. J., Wang, H. B., Chen, P., Liu, P. Q., Xu, J. Z. & Chen, H., Jan 1 2019, (Accepted/In press) In : Acta Pharmacologica Sinica.

Research output: Contribution to journalArticle

Triple Negative Breast Neoplasms
Survival
Histone-Lysine N-Methyltransferase
Disintegrins
histone methyltransferase
2 Citations (Scopus)

Overexpressed ABCB1 Induces Olaparib-Taxane Cross-Resistance in Advanced Prostate Cancer

Lombard, A. P., Liu, C., Armstrong, C. M., D'Abronzo, L. S., Lou, W., Chen, H., Dall'Era, M., Ghosh, P. M., Evans, C. P. & Gao, A. C., Jul 1 2019, In : Translational Oncology. 12, 7, p. 871-878 8 p.

Research output: Contribution to journalArticle

Open Access
Prostatic Neoplasms
Therapeutics
Poly(ADP-ribose) Polymerases
Castration
docetaxel

RORγ is a targetable master regulator of cholesterol biosynthesis in a cancer subtype

Cai, D., Wang, J., Gao, B., Li, J., Wu, F., Zou, J. X., Xu, J., Jiang, Y., Zou, H., Huang, Z., Borowsky, A. D., Bold, R. J., Lara, P. N., Li, J. J., Chen, X., Lam, K. S., To, K. F., Kung, H. J., Fiehn, O., Zhao, R. & 2 others, Evans, R. M. & Chen, H. W., Dec 1 2019, In : Nature communications. 10, 1, 4621.

Research output: Contribution to journalArticle

Open Access
biosynthesis
Biosynthesis
regulators
cholesterol
cancer