• 597 Citations
  • 13 h-Index
20082020

Research output per year

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Research Output

  • 597 Citations
  • 13 h-Index
  • 116 Article
  • 1 Chapter
  • 1 Review article
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Article
2020

Concentrations of medetomidine enantiomers and vatinoxan, an α2-adrenoceptor antagonist, in plasma and central nervous tissue after intravenous coadministration in dogs

Honkavaara, J. M., Raekallio, M. R., Syrja, P. M., Pypendop, B. H., Knych, H. K., Kallio-Kujala, I. J. & Vainio, O. M., Jan 2020, In : Veterinary Anaesthesia and Analgesia. 47, 1, p. 47-52 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

Evaluation of Orally Administered Atorvastatin on Plasma Lipid and Biochemistry Profiles in Hypercholesterolemic Hispaniolan Amazon Parrots (Amazona ventralis)

Robertson, J. A., Guzman, D. S. M., Graham, J. L., Stanhope, K. L., Douglas, J. M., Havel, P. J., Beaufrère, H., Knych, H., Tully, T. N. & Paul-Murphy, J. R., Mar 2020, In : Journal of Avian Medicine and Surgery. 34, 1, p. 32-40 9 p.

Research output: Contribution to journalArticle

Pharmacokinetics and clinical effects of xylazine and dexmedetomidine in horses recovering from isoflurane anesthesia

Guedes, A., Knych, H., Tucker, L., Almeida, D. C., Baldo, C. F., Wendt-Hornickle, E. & Allweiler, S., Jan 1 2020, (Accepted/In press) In : Journal of Veterinary Pharmacology and Therapeutics.

Research output: Contribution to journalArticle

Pharmacokinetics and pharmacodynamics of hydromorphone after intravenous and intramuscular administration in horses

Reed, R. A., Knych, H. K., Barletta, M., Sakai, D. M., Ruch, M. M., Smyth, C. A. & Ryan, C. A., Mar 2020, In : Veterinary Anaesthesia and Analgesia. 47, 2, p. 210-218 9 p.

Research output: Contribution to journalArticle

Pharmacokinetics of Intravenous and Oral Phenobarbital Sodium in Healthy Goats

Yates, L. M., Aleman, M., Knych, H. K., Knipe, M. F., Crowe, C. M. & Chigerwe, M., Feb 21 2020, In : Frontiers in Veterinary Science. 7, 86.

Research output: Contribution to journalArticle

Open Access

Pharmacokinetics of multiple doses of chloramphenicol in fed adult horses

Estell, K. E., Knych, H. K., Patel, T., Edman, J. M. & Magdesian, K. G., Mar 2020, In : Veterinary Journal. 257, 105446.

Research output: Contribution to journalArticle

2019

Characterization of the in vitro CYP450 mediated metabolism of the polymorphic CYP2D6 probe drug codeine in horses

Knych, H. K., Baden, R. W., Gretler, S. R. & McKemie, D. S., Oct 1 2019, In : Biochemical Pharmacology. 168, p. 184-192 9 p.

Research output: Contribution to journalArticle

Evaluation of the sedative effects and pharmacokinetics of detomidine gel administered intravaginally to horses

Seddighi, R., Knych, H. K., Cox, S. K., Sun, X., Moorhead, K. A. & Doherty, T. J., Jan 1 2019, (Accepted/In press) In : Veterinary Anaesthesia and Analgesia.

Research output: Contribution to journalArticle

1 Scopus citations
1 Scopus citations

Pharmacokinetics of hydroxyzine and cetirizine following oral administration of hydroxyzine to exercised Thoroughbred horses

Knych, H. K., Weiner, D., Steinmetz, S., Flynn, K. & McKemie, D. S., Jan 1 2019, (Accepted/In press) In : Journal of Veterinary Pharmacology and Therapeutics.

Research output: Contribution to journalArticle

Pharmacokinetics of maropitant citrate in New Zealand White rabbits (Oryctolagus cuniculus)

Ozawa, S. M., Hawkins, M. G., Drazenovich, T. L., Kass, P. H. & Knych, H. K., Oct 1 2019, In : American journal of veterinary research. 80, 10, p. 963-968 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

The pharmacokinetics and pharmacodynamics of intravenous hydromorphone in horses

Reed, R., Barletta, M., Mitchell, K., Hanafi, A., Bullington, A., Knych, H., Quandt, J., Ryan, C. & Giguère, S., Jan 1 2019, In : Veterinary Anaesthesia and Analgesia.

Research output: Contribution to journalArticle

4 Scopus citations
2018

5α-dihydroprogesterone concentrations and synthesis in non-pregnant mares

Conley, A. J., Scholtz, E. L., Legacki, E. L., Corbin, C. J., Knych, H. K., Dujovne, G., Ball, B. A., Moeller, B. & Stanley, S. D., Jul 1 2018, In : Journal of Endocrinology. 238, 1, p. 25-32 8 p.

Research output: Contribution to journalArticle

4 Scopus citations

Detection and pharmacokinetics of grapiprant following oral administration to exercised Thoroughbred horses

Knych, H. K., Seminoff, K. & McKemie, D. S., Aug 1 2018, In : Drug Testing and Analysis. 10, 8, p. 1237-1243 7 p.

Research output: Contribution to journalArticle

2 Scopus citations
2 Scopus citations

Equine in vivo-derived metabolites of the SARM LGD-4033 and comparison with human and fungal metabolites

Hansson, A., Knych, H. K., Stanley, S. D., Berndtson, E., Jackson, L., Bondesson, U., Thevis, M. & Hedeland, M., Feb 1 2018, In : Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 1074-1075, p. 91-98 8 p.

Research output: Contribution to journalArticle

6 Scopus citations
1 Scopus citations

L- and D-threo ethylphenidate concentrations, pharmacokinetics, and pharmacodynamics in horses

Knych, H. K., McKemie, D. S., Seminoff, K., Hartmann, P., Hovda, L. & Benson, D., Oct 1 2018, In : Drug Testing and Analysis. 10, 10, p. 1508-1517 10 p.

Research output: Contribution to journalArticle

Pharmacokinetics and efficacy of intravenous famotidine in adult cattle

Balcomb, C. C., Heller, M. C., Chigerwe, M., Knych, H. K. & Meyer, A. M., Jan 1 2018, (Accepted/In press) In : Journal of Veterinary Internal Medicine.

Research output: Contribution to journalArticle

4 Scopus citations

Pharmacokinetics of a concentrated buprenorphine formulation in red-tailed hawks (Buteo Jamaicensis)

Gleeson, M. D., Guzman, D., Knych, H. K., Kass, P. H., Drazenovich, T. L. & Hawkins, M., Jan 1 2018, In : American Journal of Veterinary Research. 79, 1, p. 13-20 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

Pharmacokinetics of buprenorphine after intravenous and oral transmucosal administration in Guinea pigs (Cavia porcellus)

Sadar, M. J., Knych, H. K., Drazenovich, T. L. & Paul-Murphy, J. R., Mar 1 2018, In : American Journal of Veterinary Research. 79, 3, p. 260-266 7 p.

Research output: Contribution to journalArticle

4 Scopus citations
2 Scopus citations
4 Scopus citations

Pharmacokinetics of intravenous flumetasone and effects on plasma hydrocortisone concentrations and inflammatory mediators in the horse

Knych, H. K., Arthur, R., McKemie, D. S., Baden, R., Oldberg, N. & Kass, P. H., Jan 1 2018, (Accepted/In press) In : Equine Veterinary Journal.

Research output: Contribution to journalArticle

1 Scopus citations

Plasma and synovial fluid concentrations and cartilage toxicity of bupivacaine following intra-articular administration of a liposomal formulation to horses

Knych, H. K., Mama, K. R., Moore, C. E., Hill, A. E. & McKEMIE, D. S., Jan 1 2018, (Accepted/In press) In : Equine Veterinary Journal.

Research output: Contribution to journalArticle

2 Scopus citations

Structural elucidation of major selective androgen receptor modulator (SARM) metabolites for doping control

Garg, N., Hansson, A., Knych, H. K., Stanley, S. D., Thevis, M., Bondesson, U., Hedeland, M. & Globisch, D., Jan 1 2018, In : Organic and Biomolecular Chemistry. 16, 5, p. 698-702 5 p.

Research output: Contribution to journalArticle

6 Scopus citations
3 Scopus citations
2017
5 Scopus citations

Effect of dexmedetomidine on the minimum infusion rate of propofol preventing movement in dogs

Smith, C. K., Seddighi, R., Cox, S. K., Sun, X., Knych, H. K. & Doherty, T. J., Nov 1 2017, In : Veterinary Anaesthesia and Analgesia. 44, 6, p. 1287-1295 9 p.

Research output: Contribution to journalArticle

3 Scopus citations

Effects of constant rate infusions of dexmedetomidine or MK-467 on the minimum alveolar concentration of sevoflurane in dogs

Hector, R. C., Rezende, M. L., Mama, K. R., Steffey, E., Knych, H. K., Hess, A. M., Honkavaara, J. M., Raekallio, M. R. & Vainio, O. M., Jul 1 2017, In : Veterinary Anaesthesia and Analgesia. 44, 4, p. 755-765 11 p.

Research output: Contribution to journalArticle

8 Scopus citations
1 Scopus citations
5 Scopus citations

Pharmacokinetics and antinociceptive effects of the soluble epoxide hydrolase inhibitor t-TUCB in horses with experimentally induced radiocarpal synovitis

Guedes, A. G. P., Aristizabal, F., Sole, A., Adedeji, A., Brosnan, R. J., Knych, H. K., Yang, J., Hwang, S. H., Morisseau, C. & Hammock, B. D., 2017, (Accepted/In press) In : Journal of Veterinary Pharmacology and Therapeutics.

Research output: Contribution to journalArticle

2 Scopus citations

Pharmacokinetics and pharmacodynamics of meldonium in exercised thoroughbred horses

Knych, H. K., Stanley, S. D., Mckemie, D. S., Arthur, R., Bondesson, U., Hedeland, M., Thevis, M. & Kass, P. H., 2017, (Accepted/In press) In : Drug Testing and Analysis.

Research output: Contribution to journalArticle

1 Scopus citations
3 Scopus citations

Pharmacokinetics of a novel, transdermal fentanyl solution in rhesus macaques (Macaca mulatta)

Salyards, G. W., Lemoy, M. J., Knych, H. K., Hill, A. E. & Christe, K. L., Jul 1 2017, In : Journal of the American Association for Laboratory Animal Science. 56, 4, p. 443-451 9 p.

Research output: Contribution to journalArticle

4 Scopus citations