• 8295 Citations
  • 43 h-Index
1981 …2019
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Fingerprint Dive into the research topics where Gino A Cortopassi is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 5 Similar Profiles
Mitochondrial DNA Medicine & Life Sciences
Friedreich Ataxia Medicine & Life Sciences
Mutation Medicine & Life Sciences
Mitochondria Chemical Compounds
Leber's Hereditary Optic Atrophy Medicine & Life Sciences
Mitochondrial Diseases Medicine & Life Sciences
Iron Medicine & Life Sciences
Genes Chemical Compounds

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Projects 1991 2017

Research Output 1981 2019

  • 8295 Citations
  • 43 h-Index
  • 120 Article
  • 3 Chapter
1 Citation (Scopus)

Dimethyl fumarate dosing in humans increases frataxin expression: A potential therapy for Friedreich’s Ataxia

Jasoliya, M., Sacca, F., Sahdeo, S., Chedin, F., Pane, C., Morra, V. B., Filla, A., Pook, M. & Cortopassi, G. A., Jun 1 2019, In : PloS one. 14, 6, e0217776.

Research output: Contribution to journalArticle

Open Access
Friedreich Ataxia
therapeutics
Gene expression
Gene Expression
gene expression
3 Citations (Scopus)

A Ketogenic Diet Extends Longevity and Healthspan in Adult Mice

Roberts, M. N., Wallace, M. A., Tomilov, A., Zhou, Z., Marcotte, G. R., Tran, D., Perez, G., Gutierrez-Casado, E., Koike, S., Knotts, T. A., Imai, D., Griffey, S. M., Kim, K., Hagopian, K., McMackin, M. Z., Haj, F., Baar, K., Cortopassi, G. A., Ramsey, J. J. & Lopez-Dominguez, J. A., Jan 1 2018, (Accepted/In press) In : Cell Metabolism.

Research output: Contribution to journalArticle

Ketogenic Diet
Manuscripts
Students
2 Citations (Scopus)

An innate immune response and altered nuclear receptor activation defines the spinal cord transcriptome during alpha-tocopherol deficiency in Ttpa-null mice

Finno, C. J., Bordbari, M. H., Gianino, G., Ming-Whitfield, B., Burns, E., Merkel, J., Britton, M., Durbin-Johnson, B., Sloma, E. A., McMackin, M., Cortopassi, G. A., Rivas, V., Barro, M., Tran, C. K., Gennity, I., Habib, H., Xu, L., Puschner, B. & Miller, A. D., May 20 2018, In : Free Radical Biology and Medicine. 120, p. 289-302 14 p.

Research output: Contribution to journalArticle

alpha-Tocopherol
Cytoplasmic and Nuclear Receptors
Transcriptome
Innate Immunity
Tocopherols
9 Citations (Scopus)

Disruption of mitochondrial function as mechanism for anti-cancer activity of a novel mitochondriotropic menadione derivative

Teixeira, J., Amorim, R., Santos, K., Soares, P., Datta, S., Cortopassi, G. A., Serafim, T. L., Sardão, V. A., Garrido, J., Borges, F. & Oliveira, P. J., Jan 15 2018, In : Toxicology. 393, p. 123-139 17 p.

Research output: Contribution to journalArticle

Vitamin K 3
Derivatives
Reactive Oxygen Species
Cell death
Molecules

Idebenone is a cytoprotective insulin sensitizer whose mechanism is Shc inhibition

Tomilov, A., Allen, S., Hui, C. K., Bettaieb, A. & Cortopassi, G. A., Nov 1 2018, In : Pharmacological Research. 137, p. 89-103 15 p.

Research output: Contribution to journalArticle

Insulin
Insulin Resistance
Proteins
Pharmaceutical Preparations
idebenone