Gerald L Denardo

Professor Emeritus

  • 8365 Citations
  • 51 h-Index
1962 …2017
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Research Output 1962 2017

1993
35 Citations (Scopus)

Radioimmunolocalization of metastatic breast carcinoma using indium-111- methyl benzyl DTPA BrE-3 monoclonal antibody: Phase I study

Kramer, E. L., DeNardo, S. J., Liebes, L., Kroger, L. A., Noz, M. E., Mizrachi, H., Salako, Q. A., Furmanski, P., Glenn, S. D., Denardo, G. L. & Ceriani, R., 1993, In : Journal of Nuclear Medicine. 34, 7, p. 1067-1074 8 p.

Research output: Contribution to journalArticle

Pentetic Acid
Indium
Monoclonal Antibodies
Breast Neoplasms
Antibodies

Rapid PCR construction of a gene containing lym-1 antibody variable regions

Shi, X. B., Gumerlock, P. H., Wellman, A. A., Meares, C. F., DeNardo, G. L., Meyers, F. J. & DeNardo, S. J., 1993, In : Genome Research. 3, 1, p. 46-53 8 p.

Research output: Contribution to journalArticle

Polymerase Chain Reaction
Antibodies
Genes
7 Citations (Scopus)

Rapid PCR construction of a gene containing Lym-1 antibody variable regions

Shi, X. B., Gumerlock, P. H., Wellman, A. A., Meares, C. F., Denardo, G. L., Meyers, F. J. & DeNardo, S. J., 1993, In : PCR Methods and Applications. 3, 1, p. 46-53 8 p.

Research output: Contribution to journalArticle

Molecular Sequence Data
Immunoglobulin Variable Region
Synthetic Genes
Immunoglobulin Light Chains
Immunoglobulin Heavy Chains
1992
36 Citations (Scopus)

Cell-mediated immunity in severely head-injured patients: The role of suppressor lymphocytes and serum factors

Quattrocchi, K. B., Miller, C. H., Wagner, F. C., DeNardo, S. J., Denardo, G. L., Ovodov, K. & Frank, E. H., 1992, In : Journal of Neurosurgery. 77, 5, p. 694-699 6 p.

Research output: Contribution to journalArticle

Cellular Immunity
Blood Cells
Head
Lymphocytes
Serum
7 Citations (Scopus)

Enhancement of clinical radioimmunotherapy for cancer and the role of cytokines

Denardo, S. J., Denardo, G. L. & Richman, C. M., Mar 18 1992, In : Journal of the National Cancer Institute. 84, 6, p. 374-375 2 p.

Research output: Contribution to journalArticle

Bone Marrow Diseases
Radioimmunotherapy
Combined Modality Therapy
Granulocyte-Macrophage Colony-Stimulating Factor
Interleukin-1
1991
36 Citations (Scopus)

Quantitative imaging of mouse L-6 monoclonal antibody in breast cancer patients to develop a therapeutic strategy

Denardo, S. J., O'Grady, L. F., Macey, D. J., Kroger, L. A., Denardo, G. L., Lamborn, K. R., Levy, N. B., Mills, S. L., Hellstrom, I. & Hellstrom, K. E., 1991, In : International Journal of Radiation Applications and Instrumentation.. 18, 6, p. 621-631 11 p.

Research output: Contribution to journalArticle

Monoclonal Antibodies
Breast Neoplasms
Radioimmunotherapy
Lung
Neoplasms
29 Citations (Scopus)

Radioimmunotherapy for breast cancer: Treatment of a patient with I-131 L6 chimeric monoclonal antibody

DeNardo, S. J., Warhoe, K. A., O'Grady, L. F., Hellstrom, I., Hellstrom, K. E., Mills, S. L., Macey, D. J., Goodnight, J. E. & DeNardo, G. L., 1991, In : International Journal of Biological Markers. 6, 4, p. 221-230 10 p.

Research output: Contribution to journalArticle

Radioimmunotherapy
Oncology
Tumors
Monoclonal Antibodies
Breast Neoplasms
20 Citations (Scopus)

Strategies for enhancement of radioimmunotherapy

Denardo, G. L., DeNardo, S., Kukis, D., Diril, H., Suey, C. & Meares, C., 1991, In : International Journal of Radiation Applications and Instrumentation.. 18, 6

Research output: Contribution to journalArticle

Radioimmunotherapy
Neoplasms
Nude Mice
Interleukin-2
Copper
1990
22 Citations (Scopus)

A treatment planning program for radioimmunotherapy.

Macey, D. J., Denardo, G. L. & DeNardo, S. J., 1990, In : Frontiers of Radiation Therapy and Oncology. 24, p. 123-131 9 p.

Research output: Contribution to journalArticle

Computer-Assisted Radiotherapy Planning
Computer-Assisted Radiotherapy
Iodine Radioisotopes
Radiation Dose-Response Relationship
Radioimmunotherapy
134 Citations (Scopus)

Fractionated radioimmunotherapy of B-cell malignancies with131I-lym-1

Denardo, G. L., DeNardo, S. J., O'Grady, L. F., Levy, N. B., Adams, G. P. & Mills, S. L., 1990, In : Cancer Research. 50, 3 SUPPL.

Research output: Contribution to journalArticle

Radioimmunotherapy
B-Lymphocytes
Burkitt Lymphoma
Neoplasms
Cell Nucleus
68 Citations (Scopus)

Metabolism of indium chelates attached to monoclonal antibody: Minimal transchelation of indium from benzyl-EDTA chelate in vivo

Deshpande, S. V., Subramanian, R., McCall, M. J., DeNardo, S. J., Denardo, G. L. & Meares, C. F., 1990, In : Journal of Nuclear Medicine. 31, 2, p. 218-224 7 p.

Research output: Contribution to journalArticle

Indium
Monoclonal Antibodies
Antibodies
Radioimmunodetection
Pentetic Acid
1 Citation (Scopus)

Quo vadis radioimmune imaging? (I)

Denardo, G. L. & DeNardo, S. J., 1990, In : Journal of Nuclear Medicine. 31, 8, p. 1439-1441 3 p.

Research output: Contribution to journalLetter

Antibodies
Neoplasms
13 Citations (Scopus)

Radiation treatment of B cell malignancies with immunoconjugate.

Denardo, G. L., DeNardo, S. J., O'Grady, L. F., Mills, S. L., Lewis, J. P. & Macey, D. J., 1990, In : Frontiers of Radiation Therapy and Oncology. 24, p. 194-201 8 p.

Research output: Contribution to journalArticle

Iodine Radioisotopes
Immunoconjugates
B-Cell Leukemia
Immunotoxins
Immunotherapy

Today and tomorrow: radiochemistry for radioimmunotherapy of breast cancer.

DeNardo, S. J., Deshpande, S. V., Moi, M. K., Adamas, G. P., McCall, M. K., Denardo, G. L. & Meares, C. F., 1990, In : Frontiers of Radiation Therapy and Oncology. 24, p. 142-150 9 p.

Research output: Contribution to journalArticle

Yttrium Radioisotopes
Copper Radioisotopes
Radiochemistry
Radioimmunotherapy
Immunotoxins
168 Citations (Scopus)

Yttrium-90-labeled monoclonal antibody for therapy: labeling by a new macrocyclic bifunctional chelating agent

Deshpande, S. V., DeNardo, S. J., Kukis, D. L., Moi, M. K., McCall, M. J., Denardo, G. L. & Meares, C. F., 1990, In : Journal of Nuclear Medicine. 31, 4, p. 473-479 7 p.

Research output: Contribution to journalArticle

Yttrium
Chelating Agents
Monoclonal Antibodies
Ligands
Bone and Bones
1989
18 Citations (Scopus)

Current status of immunoscintigraphy in the detection of thrombosis and thromboembolism

Koblik, P. D., Denardo, G. L. & Berger, H. J., 1989, In : Seminars in Nuclear Medicine. 19, 3, p. 221-237 17 p.

Research output: Contribution to journalArticle

Thromboembolism
Thrombosis
Antibodies
Blood Platelets
Immunoglobulin Fragments
36 Citations (Scopus)

Effect of different linkages between chelates and monoclonal antibodies on levels of radioactivity in the liver

Deshpande, S. V., Denardo, S. J., Meares, C. F., Mccall, M. J., Adams, G. P. & Denardo, G. L., 1989, In : International Journal of Radiation Applications and Instrumentation.. 16, 6, p. 587-597 11 p.

Research output: Contribution to journalArticle

Radioactivity
Monoclonal Antibodies
Thiourea
Injections
Antibodies
30 Citations (Scopus)

Effect of mass of 111In-benzyl-EDTA monoclonal antibody on hepatic uptake and processing in mice

Adams, G. P., DeNardo, S. J., Deshpande, S. V., Denardo, G. L., Meares, C. F., McCall, M. J. & Epstein, A. L., 1989, In : Cancer Research. 49, 7, p. 1707-1711 5 p.

Research output: Contribution to journalArticle

Monoclonal Antibodies
Radiopharmaceuticals
Pharmacokinetics
Liver
Burkitt Lymphoma

Monoclonal antibodies in imaging

Raventos, A., Denardo, G. L. & Denardo, S., 1989, In : Postgraduate Radiology. 9, 4, p. 225-237 13 p.

Research output: Contribution to journalArticle

Monoclonal Antibodies
Antibodies
Immunoglobulin Fragments
Indium
Neoplasm Staging
10 Citations (Scopus)

Pharmaceutical quality control of radiolabeled monoclonal antibodies and their fragments

DeNardo, S. J., Denardo, G. L. & Peng, J. S., 1989, In : American Journal of Physiologic Imaging. 4, 1, p. 39-44 6 p.

Research output: Contribution to journalReview article

Emission-Computed Tomography
Isotope Labeling
Immunoglobulin Fragments
Radioisotopes
Quality Control
26 Citations (Scopus)

Quantitative SPECT of uptake of monoclonal antibodies

Denardo, G. L., Macey, D. J., DeNardo, S. J., Zhang, C. G. & Custer, T. R., 1989, In : Seminars in Nuclear Medicine. 19, 1, p. 22-32 11 p.

Research output: Contribution to journalArticle

Single-Photon Emission-Computed Tomography
Monoclonal Antibodies
Antibodies
Radioisotopes
Research
4 Citations (Scopus)

Radiopharmaceutical preparation of a monoclonal antibody, Lym-1, and its F(ab')2 fragment for imaging lymphoma with In-111

Mills, S. L., De Nardo, S. J., Denardo, G. L., Deshpande, S. V., McCall, M., Meares, C. & Epstein, A. L., 1989, In : Journal of Labelled Compounds and Radiopharmaceuticals. 27, 4, p. 377-386 10 p.

Research output: Contribution to journalArticle

Cyanates
Radiopharmaceuticals
Lymphoma
Imaging techniques
Molecules
1988
20 Citations (Scopus)

Comparison of three boundary detection methods for SPECT using Compton scattered photons

Macey, D. J., Denardo, G. L. & DeNardo, S. J., 1988, In : Journal of Nuclear Medicine. 29, 2, p. 203-207 5 p.

Research output: Contribution to journalArticle

Single-Photon Emission-Computed Tomography
Photons
Gamma Cameras
Human Body
Radioisotopes
103 Citations (Scopus)

Copper-67-labeled monoclonal antibody Lym-1, a potential radiopharmaceutical for cancer therapy: Labeling and biodistribution in RAJI tumored mice

Desphande, S. V., DeNardo, S. J., Meares, C. F., McCall, M. J., Adams, G. P., Moi, M. K. & Denardo, G. L., 1988, In : Journal of Nuclear Medicine. 29, 2, p. 217-225 9 p.

Research output: Contribution to journalArticle

Radiopharmaceuticals
Radioimmunotherapy
Copper
B-Cell Lymphoma
Beta Particles
87 Citations (Scopus)

Direct dose confirmation of quantitative autoradiography with micro-TLD measurements for radioimmunotherapy

Griffith, M. H., Yorke, E. D., Wessels, B. W., Denardo, G. L. & Neacy, W. P., 1988, In : Journal of Nuclear Medicine. 29, 11, p. 1795-1809 15 p.

Research output: Contribution to journalArticle

Radioimmunotherapy
Autoradiography
Neoplasm Antibodies
B-Cell Lymphoma
Radioactivity
17 Citations (Scopus)

Non-dehalogenation mechanisms for excretion of radioiodine after administration of labeled antibodies.

Denardo, G. L., De Nardo, S. J., Miyao, N. P., Mills, S. L., Peng, J. S., O'Grady, L. F., Epstein, A. L. & Young, W. C., Jan 1988, In : International Journal of Biological Markers. 3, 1, p. 1-9 9 p.

Research output: Contribution to journalArticle

Antibodies
Halogenation
Dehalogenation
Indium
Pharmacokinetics
111 Citations (Scopus)

Treatment of B cell malignancies with 131I LYM‐1 monoclonal antibodies

Denardo, S. J., Denardo, G. L., O'Grady, L. F., Hu, E., Sytsma, V. M., Mills, S. L., Levy, N. B., Macey, D. J., Miller, C. H. & Epstein, A. L., 1988, In : International Journal of Cancer. 41, 3 S, p. 96-101 6 p.

Research output: Contribution to journalArticle

B-Lymphocytes
Monoclonal Antibodies
Neoplasms
Therapeutics
Burkitt Lymphoma
30 Citations (Scopus)

Uptake of indium-111-labeled monoclonal antibody ZME-018 as a function of tumor size in a patient with melanoma

Macey, D. J., Denardo, S. J., Denardo, G. L., Goodnight Jr, J. E. & Unger, M. W., 1988, In : American Journal of Physiologic Imaging. 3, 1, p. 1-6 6 p.

Research output: Contribution to journalArticle

Indium
Melanoma
Monoclonal Antibodies
Neoplasms
Radioimmunodetection
1987
1 Citation (Scopus)

Prospects for radiolabeled monoclonal antibodies in metastatic disease

Raventos, A., DeNardo, S. J. & Denardo, G. L., 1987, In : Journal of Thoracic Imaging. 2, 4, p. 44-49 6 p.

Research output: Contribution to journalArticle

Monoclonal Antibodies
Antibodies
Radioimmunotherapy
Neoplasms
Gamma Cameras
77 Citations (Scopus)

Treatment of a patient with B cell lymphoma by I-131 LYM-1 monoclonal antibodies.

DeNardo, S. J., Denardo, G. L., O'Grady, L. F., Macey, D. J., Mills, S. L., Epstein, A. L., Peng, J. S. & McGahan, J. P., Jan 1987, In : International Journal of Biological Markers. 2, 1, p. 49-53 5 p.

Research output: Contribution to journalArticle

B-Cell Lymphoma
Tumors
Monoclonal Antibodies
Cells
Agranulocytosis
1986
6 Citations (Scopus)

123I radiolabeling of monoclonal antibodies for in vivo procedures

Mills, S. L., Denardo, S. J. & Denardo, G. L., 1986, In : Hybridoma. 5, 4, p. 265-275 11 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Comparison of low- and medium-energy collimators for SPECT imaging with iodine-123-labeled antibodies

Macey, D. J., Denardo, G. L., DeNardo, S. J. & Hines, H. H., 1986, In : Journal of Nuclear Medicine. 27, 9, p. 1467-1474 8 p.

Research output: Contribution to journalArticle

Single-Photon Emission-Computed Tomography
Iodine
Antibodies
Artifacts
Air
36 Citations (Scopus)

Immunochemical aspects of monoclonal antibodies important for radiopharmaceutical development

DeNardo, S. J., Peng, J. S., Denardo, G. L., Mills, S. L. & Epstein, A. L., 1986, In : Nuclear Medicine and Biology. 13, 4, p. 303-310 8 p.

Research output: Contribution to journalArticle

Radiopharmaceuticals
Monoclonal Antibodies
Hybridomas
Affinity Chromatography
Radioimmunoassay
14 Citations (Scopus)

Immunochemical aspects of monoclonal antibodies important for radiopharmaceutical development

DeNardo, S. J., Peng, J. S. B., Denardo, G. L., Mills, S. L. & Epstein, A. L., 1986, In : International Journal of Radiation Applications and Instrumentation.. 13, 4

Research output: Contribution to journalArticle

Radiopharmaceuticals
Monoclonal Antibodies
Hybridomas
Affinity Chromatography
Radioimmunoassay
2 Citations (Scopus)

MODIFIED POST PROCESSING CORRECTION MATRIX FOR SPECT.

Macey, D. J., DeNardo, G. L., DeNardo, S. J. & Seibert, J. A., 1986, Proceedings of SPIE - The International Society for Optical Engineering. Vol. 671. p. 189-192 4 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Single photon emission computed tomography
tomography
Pixels
attenuation
pixels
37 Citations (Scopus)

Multicompartmental analysis of the kinetics of radioiodinated monoclonal antibody in patients with cancer

Koizumi, K., Denardo, G. L., DeNardo, S. J., Hays, M. T., Hines, H. H., Scheibe, P. O., Peng, J. S., Macey, D. J., Tonami, N. & Hisada, K., 1986, In : Journal of Nuclear Medicine. 27, 8, p. 1243-1254 12 p.

Research output: Contribution to journalArticle

Monoclonal Antibodies
Antibodies
Neoplasms
Immunoglobulins
B-Cell Lymphoma
14 Citations (Scopus)

Radiolabelled monoclonal antibodies for the detection of cancer

O'Grady, L. F., Denardo, G. L. & DeNardo, S., 1986, In : American Journal of Physiologic Imaging. 1, 1, p. 44-53 10 p.

Research output: Contribution to journalReview article

Emission-Computed Tomography
Isotope Labeling
Neoplasm Antigens
Monoclonal Antibodies
Neoplasms
1985
19 Citations (Scopus)

31P Surface‐Coil NMR Analysis of Metabolic Status in KHJJ Tumors

Adams, D. A., Denardo, G. L., Denardo, S. J., Conboy, C. B. & Morton Bradbury, E., 1985, In : Magnetic Resonance in Medicine. 2, 5, p. 419-427 9 p.

Research output: Contribution to journalArticle

Mental Competency
Radioimmunotherapy
Neoplasms
Adenosine Triphosphate
Tumor Burden
1 Citation (Scopus)

Correlation of bioscintigraphy, contrast venography, and iodine-125 fibrinogen uptake test

Denardo, G. L., DeNardo, S. J., Carretta, R. F., Bogren, H. G., Jansholt, A. L., Krohn, K. A. & Peek, N. F., 1985, In : Clinical Nuclear Medicine. 10, 12, p. 880-883 4 p.

Research output: Contribution to journalArticle

Phlebography
Venous Thrombosis
Iodine
Fibrinogen
Heparin
5 Citations (Scopus)

Detection of thrombophlebitis in the lower extremities: A regional comparison of 123I fibrinogen scintigraphy and contrast venography

DeNardo, S. J., Bogren, H. G. & Denardo, G. L., 1985, In : American Journal of Roentgenology. 145, 5, p. 1045-1052 8 p.

Research output: Contribution to journalArticle

Thrombophlebitis
Phlebography
Radionuclide Imaging
Fibrinogen
Lower Extremity
11 Citations (Scopus)

Radioimmunotherapy of human lymphoma in athymic, nude mice as monitored by 31P nuclear magnetic resonance

Adams, D. A., Denardo, G. L., DeNardo, S. J., Matson, G. B., Epstein, A. L. & Bradbury, E. M., Sep 16 1985, In : Biochemical and Biophysical Research Communications. 131, 2, p. 1020-1027 8 p.

Research output: Contribution to journalArticle

Radioimmunotherapy
Nude Mice
Tumors
Lymphoma
Magnetic Resonance Spectroscopy
44 Citations (Scopus)

Requirements for a treatment planning system for radioimmunotherapy

Denardo, G. L., Raventos, A., Hines, H. H., Scheibe, P. O., Macey, D. J., Hays, M. T. & Denardo, S. J., 1985, In : International Journal of Radiation Oncology, Biology, Physics. 11, 2, p. 335-348 14 p.

Research output: Contribution to journalArticle

Radioimmunotherapy
Radioisotopes
planning
antibodies
radioactive isotopes
1983
1 Citation (Scopus)

The future of radioiodines

Denardo, G. L., Sep 1983, In : Journal of Radioanalytical Chemistry. 76, 2, p. 337-340 4 p.

Research output: Contribution to journalArticle

1982
6 Citations (Scopus)

Bronchoscopic location of bronchopleural fistula with Xenon 133

Lillington, G., Stevens, R. P. & Denardo, G. L., 1982, In : Journal of Nuclear Medicine. 23, 4, p. 322-323 2 p.

Research output: Contribution to journalArticle

Xenon
Bronchi
Fistula
Bronchoscopes
Radioactivity
1 Citation (Scopus)

Development of pure, homogeneous monoclonal antibody fragments as a resource for radiopharmaceuticals

Peng, J. S., DeNardo, S. & Denardo, G. L., 1982, In : Journal of Nuclear Medicine. 23, 5

Research output: Contribution to journalArticle

Immunoglobulin Fragments
Radiopharmaceuticals
Monoclonal Antibodies
1981
2 Citations (Scopus)

Thrombosis detection: Fibrinogen counting and radionuclide venography

Denardo, G. L. & DeNardo, S. J., 1981, In : Clinical Nuclear Medicine. Vol. 6, Suppl. 10

Research output: Contribution to journalArticle

Phlebography
Radioisotopes
Fibrinogen
Thrombosis
Venous Thrombosis
1980
10 Citations (Scopus)

Immediate renal imaging and renography with 99mTc methylene diphosphonate to assess renal blood flow, excretory function, and anatomy

Glass, E. C., Denardo, G. L. & Hines, H. H., 1980, In : Radiology. 135, 1, p. 187-190 4 p.

Research output: Contribution to journalArticle

Radioisotope Renography
Technetium Tc 99m Medronate
Renal Circulation
Radionuclide Imaging
Anatomy
56 Citations (Scopus)

Noninvasive measurement of pulmonary transvascular protein flux in normal man

Gorin, A. B., Kohler, J. & Denardo, G. L., 1980, In : Journal of Clinical Investigation. 66, 5, p. 869-877 9 p.

Research output: Contribution to journalArticle

Lung
Proteins
Transferrin
Sheep
Porosity
1979
Thallium
Radioisotopes
Coronary Disease
Heart Rate
1978
9 Citations (Scopus)

Abnormal peripheral distribution of thallium-201 due to arteriosclerosis

Glass, E. C. & Denardo, G. L., 1978, In : American Journal of Roentgenology. 131, 4, p. 718-720 3 p.

Research output: Contribution to journalArticle

Subclavian Steal Syndrome
Arteriosclerosis
Thallium
Body Image