Gerald L Denardo

Professor Emeritus

  • 8496 Citations
  • 51 h-Index
1962 …2018

Research output per year

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Research Output

1998

Synergistic therapy of breast cancer with Y90-chimeric L6 and paclitaxel in the xenografted mouse model: Development of a clinical protocol

DeNardo, S. J., Richman, C. M., Kukis, D. L., Shen, S., Lamborn, K. R., Miers, L. A., Kroger, L. A., Perez, E. A. & Denardo, G. L., 1998, In : Anticancer Research. 18, 6 A, p. 4011-4018 8 p.

Research output: Contribution to journalArticle

29 Scopus citations

Yttrium-90-DOTA-peptide-chimeric L6 radioimmunoconjugate: Efficacy and toxicity in mice bearing p53 mutant human breast cancer xenografts

DeNardo, S. J., Kukis, D. L., Miers, L. A., Winthrop, M. D., Kroger, L. A., Salako, Q., Shen, S., Lamborn, K. R., Gumerlock, P. H., Meares, C. F. & DeNardo, G. L., May 1998, In : Journal of Nuclear Medicine. 39, 5, p. 842-849 8 p.

Research output: Contribution to journalArticle

42 Scopus citations
1997

Decreased C-MYC and BCL2 expression correlates with methylprednisolone- mediated inhibition of Raji lymphoma growth

Morris, G., Denardo, S. J., Denardo, G. L., Leshchinsky, T., Wu, B., Mack, P., Winthrop, M. D. & Gumerlock, P. H., Apr 1997, In : Biochemical and Molecular Medicine. 60, 2, p. 108-115 8 p.

Research output: Contribution to journalArticle

5 Scopus citations

Efficacy and toxicity of 67Cu-2IT-BAT-Lym-1 radioimmunoconjugate in mice implanted with human Burkitt's lymphoma (Raji)

Denardo, G. L., Kukis, D. L., Shen, S., Mausner, L. F., Meares, C. F., Srivastava, S. C., Miers, L. A. & DeNardo, S. J., 1997, In : Clinical Cancer Research. 3, 1, p. 71-79 9 p.

Research output: Contribution to journalArticle

51 Scopus citations

Enhancement of 67Cu-2IT-BAT-LYM-1 therapy in mice with human Burkitt's lymphoma (Raji) using interleukin-2

Denardo, G. L., Kukis, D. L., DeNardo, S. J., Shen, S., Mausner, L. F., O'Donnell, R. T., Lamborn, K. R., Meyers, F. J., Srivastava, S. C. & Miers, L. A., Dec 15 1997, In : Cancer. 80, 12 SUPPL., p. 2576-2582 7 p.

Research output: Contribution to journalArticle

11 Scopus citations

Imaging for improved prediction of myelotoxicity after radioimmunotherapy

DeNardo, D. A., Denardo, G. L., O'Donnell, R. T., Lim, S. M., Shen, S., Yuan, A. & DeNardo, S. J., Dec 15 1997, In : Cancer. 80, 12 SUPPL., p. 2558-2566 9 p.

Research output: Contribution to journalArticle

28 Scopus citations

Impact of splenomegaly on therapeutic response and I-131-LYM-1 dosimetry in patients B-lymphocytic malignancies

Shen, S., Denardo, G. L., O'Donnell, R. T., Yuan, A., DeNardo, D. A. & DeNardo, S. J., Dec 15 1997, In : Cancer. 80, 12 SUPPL., p. 2553-2557 5 p.

Research output: Contribution to journalArticle

16 Scopus citations

Importance of temporal relationships in combined modality radioimmunotherapy of breast carcinoma

DeNardo, S. J., Kroger, L. A., Lamborn, K. R., Miers, L. A., O'Donnell, R. T., Kukis, D. L., Richman, C. M. & Denardo, G. L., Dec 15 1997, In : Cancer. 80, 12 SUPPL., p. 2583-2590 8 p.

Research output: Contribution to journalArticle

25 Scopus citations

Increased survival associated with radiolabeled Lym-1 therapy for non- Hodgkin's lymphoma and chronic lymphocytic leukemia

Denardo, G. L., Lamborn, K. R., Goldstein, D. S., Kroger, L. A. & DeNardo, S. J., Dec 15 1997, In : Cancer. 80, 12 SUPPL., p. 2706-2711 6 p.

Research output: Contribution to journalArticle

61 Scopus citations

Peripheral blood stem cell mobilization for hematopoietic support of radioimmunotherapy in patients with breast carcinoma

Richman, C. M., Schuermann, T. C., Wun, T., Malik, R., O'Donnell, R. T., Denardo, G. L. & DeNardo, S. J., Dec 15 1997, In : Cancer. 80, 12 SUPPL., p. 2728-2732 5 p.

Research output: Contribution to journalArticle

9 Scopus citations

Practical determination of organ S values for individual patients for therapy

Shen, S., Denardo, G. L., Macey, D. J., O'Donnell, R. T., Yuan, A., DeNardo, D. A. & DeNardo, S. J., Jul 1997, In : Nuclear Medicine and Biology. 24, 5, p. 447-449 3 p.

Research output: Contribution to journalArticle

8 Scopus citations

Prediction of myelotoxicity using radiation doses to marrow from body, blood and marrow sources

Lim, S. M., DeNardo, G. L., DeNardo, D. A., Shen, S., Yuan, A., O'Donnell, R. T. & DeNardo, S. J., Sep 1997, In : Journal of Nuclear Medicine. 38, 9, p. 1374-1378 5 p.

Research output: Contribution to journalArticle

43 Scopus citations

Prediction of myelotoxicity using semi-quantitative marrow image scores

Lim, S., DeNardo, G. L., DeNardo, D. A., O'Donnell, R. T., Yuan, A. & DeNardo, S. J., Nov 1997, In : Journal of Nuclear Medicine. 38, 11, p. 1749-1753 5 p.

Research output: Contribution to journalArticle

11 Scopus citations

Radioimmunotherapy for advanced breast cancer using I-131-ChL6 antibody

Denardo, S. J., O'Grady, L. F., Richman, C. M., Goldstein, D. S., O'Donnell, R. T., Denardo, D. A., Kroger, L. A., Lamborn, K. R., Hellström, K. E., Hellström, I. & Denardo, G. L., 1997, In : Anticancer Research. 17, 3 B, p. 1745-1751 7 p.

Research output: Contribution to journalArticle

62 Scopus citations

Radioimmunotherapy for breast cancer using indium- 111/Yttrium-90 BrE- 3: Results of a phase I clinical trial

DeNardo, S. J., Kramer, E. L., O'Donnell, R. T., Richman, C. M., Salako, Q. A., Shen, S., Noz, M., Glenn, S. D., Ceriani, R. L. & Denardo, G. L., 1997, In : Journal of Nuclear Medicine. 38, 8, p. 1180-1185 6 p.

Research output: Contribution to journalArticle

93 Scopus citations

Reproducibility of operator processing for radiation dosimetry

Shen, S., Denardo, G. L., DeNardo, S. J., Yuan, A., DeNardo, D. A. & Lamborn, K. R., Jan 1997, In : Nuclear Medicine and Biology. 24, 1, p. 77-83 7 p.

Research output: Contribution to journalArticle

20 Scopus citations

Synergy of Taxol and radioimmunotherapy with yttrium-90-labeled chimeric L6 antibody: Efficacy and toxicity in breast cancer xenografts

Denardo, S. J., Kukis, D. L., Kroger, L. A., O'Donnell, R. T., Lamborn, K. R., Miers, L. A., Denardo, D. G., Meares, C. F. & Denardo, G. L., Apr 15 1997, In : Proceedings of the National Academy of Sciences of the United States of America. 94, 8, p. 4000-4004 5 p.

Research output: Contribution to journalArticle

103 Scopus citations

Treatment-related parameters predicting efficacy of Lym-1 radioimmunotherapy in patients with B-lymphocytic malignancies

Lamborn, K. R., Denardo, G. L., DeNardo, S. J., Goldstein, D. S., Shen, S., Larkin, E. C. & Kroger, L. A., Aug 1997, In : Clinical Cancer Research. 3, 8, p. 1253-1260 8 p.

Research output: Contribution to journalArticle

28 Scopus citations

Trials and tribulations: Oncological antibody imaging comes to the fore

Zuckier, L. S. & Denardo, G. L., 1997, In : Seminars in Nuclear Medicine. 27, 1, p. 10-29 20 p.

Research output: Contribution to journalReview article

56 Scopus citations

Tribute to Ralph A. Reisfeld, Ph.D.

Denardo, G. L., Dec 15 1997, In : Cancer. 80, 12 Suppl, p. 2345-2346 2 p.

Research output: Contribution to journalArticle

Yttrium-90/indium-111-DOTA-peptide-chimeric L6: Pharmacokinetics, dosimetry and initial results in patients with incurable breast cancer

Denardo, S. J., Richman, C. M., Goldstein, D. S., Shen, S., Sajlako, Q., Kukis, D. L., Meares, C. F., Yuan, A., Welborn, J. L. & Denardo, G. L., 1997, In : Anticancer Research. 17, 3 B, p. 1735-1744 10 p.

Research output: Contribution to journalArticle

78 Scopus citations
1996

Accurate measurement of copper-67 in the presence of copper-64 contaminant using a dose calibrator

Denardo, G. L., Kukis, D. L., Shen, S. & DeNardo, S. J., Feb 1996, In : Journal of Nuclear Medicine. 37, 2, p. 302-306 5 p.

Research output: Contribution to journalArticle

8 Scopus citations

Antibody responses to macrocycles in lymphoma

DeNardo, G. L., Mirick, G. R., Kroger, L. A., O'Donnell, R. T., Meares, C. F. & DeNardo, S. J., Mar 1996, In : Journal of Nuclear Medicine. 37, 3, p. 451-456 6 p.

Research output: Contribution to journalArticle

59 Scopus citations

Application of the linear-quadratic model to myelotoxicity associated with radioimmunotherapy

Wilder, R. B., Denardo, G. L., Sheri, S., Fowler, J. F., Wessels, B. W. & DeNardo, S. J., 1996, In : European Journal Of Nuclear Medicine. 23, 8, p. 953-957 5 p.

Research output: Contribution to journalArticle

5 Scopus citations

A radioimmunoimaging and MIRD dosimetry treatment planning program for radioimmunotherapy

Erwin, W. D., Groch, M. W., Macey, D. J., Denardo, G. L., DeNardo, S. J. & Shen, S., May 1996, In : Nuclear Medicine and Biology. 23, 4, p. 525-532 8 p.

Research output: Contribution to journalArticle

41 Scopus citations

Dosimetric evaluation of copper-64 in copper-67-2IT-BAT-Lym-1 for radioimmunotherapy

Shen, S., Denardo, G. L., DeNardo, S. J., Salako, Q., Morris, G., Banks, D., Yuan, A. & DeNardo, D. A., Jan 1996, In : Journal of Nuclear Medicine. 37, 1, p. 146-150 5 p.

Research output: Contribution to journalArticle

26 Scopus citations

Lymphoma-selective antibody Lym-1 recognizes a discontinuous epitope on the light chain of HLA-DR10

Rose, L. M., Gunasekera, A. H., DeNardo, S. J., Denardo, G. L. & Meares, C. F., 1996, In : Cancer Immunology Immunotherapy. 43, 1, p. 26-30 5 p.

Research output: Contribution to journalArticle

58 Scopus citations

Prediction of radiation doses from therapy using tracer studies with iodine-131-labeled antibodies

DeNardo, D. A., DeNardo, G. L., Yuan, A., Shen, S., DeNardo, S. J., Macey, D. J., Lamborn, K. R., Mahe, M., Groch, M. W. & Erwin, W. D., Dec 1996, In : Journal of Nuclear Medicine. 37, 12, p. 1970-1975 6 p.

Research output: Contribution to journalArticle

36 Scopus citations

Radioimmunotherapy: Recent results and future directions

Wilder, R. B., Denardo, G. L. & DeNardo, S. J., Apr 1996, In : Journal of Clinical Oncology. 14, 4, p. 1383-1400 18 p.

Research output: Contribution to journalReview article

136 Scopus citations
1995

Analysis of antiglobulin (HAMA) response in a group of patients with B-lympkocytic malignancies treated with 131I-Lym-1

Denardo, G. L., Kroger, L. A., Mirick, G. R., Lamborn, K. R. & De Nardo, S. J., 1995, In : International Journal of Biological Markers. 10, 2, p. 67-74 8 p.

Research output: Contribution to journalArticle

27 Scopus citations

Effect of the extent of chelate substitution on the immunoreactivity and biodistribution of 2IT-BAT-Lym-1 immunoconjugates

Kukis, D. L., Denardo, G. L., DeNardo, S. J., Mirick, G. R., Miers, L. A., Greiner, D. P. & Meares, C. F., 1995, In : Cancer Research. 55, 4, p. 878-884 7 p.

Research output: Contribution to journalArticle

97 Scopus citations

Estimation of radiation absorbed doses to the red marrow in radioimmunotherapy

Macey, D. J., DeNardo, S. J., Denardo, G. L., DeNardo, D. A. & Shen, S., 1995, In : Clinical Nuclear Medicine. 20, 2, p. 117-125 9 p.

Research output: Contribution to journalArticle

35 Scopus citations
37 Scopus citations

Pharmacokinetics and normal organ dosimetry following intraperitoneal rhenium-186-labeled monoclonal antibody

Breitz, H. B., Durham, J. S., Fisher, D. R., Weiden, P. L., Denardo, G. L., Goodgold, H. M. & Nelp, W. B., 1995, In : Journal of Nuclear Medicine. 36, 5, p. 754-761 8 p.

Research output: Contribution to journalArticle

21 Scopus citations

Pharmacokinetics of chimeric L6 conjugated to indium-111- and yttrium-90- DOTA-peptide in tumor-bearing mice

DeNardo, S. J., Zhong, G. R., Salako, Q., Li, M., Denardo, G. L. & Meares, C. F., 1995, In : Journal of Nuclear Medicine. 36, 5, p. 829-836 8 p.

Research output: Contribution to journalArticle

57 Scopus citations

Prognostic factors for radioimmunotherapy in patients with B-lymphocytic malignancies

Denardo, G. L., Lamborn, K. R., DeNardo, S. J., Goldstein, D. S., Dolber-Smith, E. G., Kroger, L. A., Larkin, E. C. & Shen, S., 1995, In : Cancer Research. 55, 23 SUPPL.

Research output: Contribution to journalArticle

19 Scopus citations
60 Scopus citations

Radioimmunotherapy of lymphoma: A UC Davis experience

Lewis, J. P., Denardo, G. L. & Denardo, S. J., 1995, In : Hybridoma. 14, 2, p. 115-120 6 p.

Research output: Contribution to journalArticle

34 Scopus citations

Review of a four-year experience iodinating monoclonal antibodies with therapeutic amounts of I-131

Denardo, G. L., Mills, S. L., Kukis, D. L., Anderson, V. & DeNardo, S. J., 1995, In : Antibody, Immunoconjugates, and Radiopharmaceuticals. 8, 1, p. 1-10 10 p.

Research output: Contribution to journalReview article

9 Scopus citations

Yttrium-90 chimeric L6 therapy of human breast cancer in nude mice and apoptosis-related messenger RNA expression

DeNardo, S. J., Gumerlock, P. H., Winthrop, M. D., Mack, P., Chi, S. G., Lamborn, K. R., Shen, S., Miers, L. A., deVere White, R. W. & Denardo, G. L., 1995, In : Cancer Research. 55, 23 SUPPL.

Research output: Contribution to journalArticle

18 Scopus citations
1994

A comparative study of copper-67 radiolabeling and kinetic stabilities of antibody-macrocycle chelate conjugates

Kukis, D. L., Diril, H., Greiner, D. P., DeNardo, S. J., Denardo, G. L., Salako, Q. A. & Meares, C. F., 1994, In : Cancer. 73, SUPPL., p. 779-786 8 p.

Research output: Contribution to journalArticle

62 Scopus citations

Comparative toxicity studies of yttrium-90 MX-DTPA and 2-IT-BAD conjugated monoclonal antibody (BrE-3)

Denardo, G. L., Kroger, L. A., DeNardo, S. J., Miers, L. A., Salako, Q., Kukis, D. L., Fand, I., Shen, S., Renn, O. & Meares, C. F., 1994, In : Cancer. 73, SUPPL., p. 1012-1022 11 p.

Research output: Contribution to journalArticle

61 Scopus citations

Effect of lym‐1 radioimmunoconjugate on refractory chronic lymphocytic leukemia

Denardo, G. L., Lewis, J. P., Denardo, S. J. & O'Grady, L. F., 1994, In : Cancer. 73, 5, p. 1425-1432 8 p.

Research output: Contribution to journalArticle

54 Scopus citations

Overview of radiation myelotoxicity secondary to radioimmunotherapy using 131 i‐lym‐1 as a model

Denardo, G. L., Denardo, S. J., Macey, D. J., Shen, S. & Kroger, L. A., 1994, In : Cancer. 73, 3 S, p. 1038-1048 11 p.

Research output: Contribution to journalArticle

47 Scopus citations

Overview of radioimmunotherapy in advanced breast cancer using I-131 chimeric L6

DeNardo, S. J., O'Grady, L. F., Richman, C. M. & Denardo, G. L., 1994, In : Advances in Experimental Medicine and Biology. 353, p. 203-211 9 p.

Research output: Contribution to journalArticle

18 Scopus citations

Planar gamma camera imaging and quantitation of yttrium-90 bremsstrahlung

Shen, S., DeNardo, G. L., Yuan, A., DeNardo, D. A. & DeNardo, S. J., 1994, In : Journal of Nuclear Medicine. 35, 8, p. 1381-1389 9 p.

Research output: Contribution to journalArticle

71 Scopus citations

Quantitative bremsstrahlung imaging of yttrium-90 using a wiener

Shen, S., Denardo, G. L. & DeNardo, S. J., 1994, In : Medical Physics. 21, 9, p. 1409-1417 9 p.

Research output: Contribution to journalArticle

46 Scopus citations

The biologic window for chimeric L6 radioimmunotherapy

DeNardo, S. J., Mirick, G. R., Kroger, L. A., O'Grady, L. F., Erickson, K. L., Yuan, A., Lamborn, K. R., Hellstrom, I., Hellstrom, K. E. & Denardo, G. L., 1994, In : Cancer. 73, SUPPL., p. 1023-1032 10 p.

Research output: Contribution to journalArticle

59 Scopus citations

Treatment of cancer with intratumoral infusion of radioisotopes

Wilder, R. B., Denardo, G. L. & Denardo, S. J., Oct 15 1994, In : International Journal of Radiation Oncology, Biology, Physics. 30, 3, p. 737-739 3 p.

Research output: Contribution to journalEditorial

2 Scopus citations