Gerald L Denardo

Professor Emeritus

  • 8496 Citations
  • 51 h-Index
1962 …2018

Research output per year

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Research Output

2000

Antibody phage display applications for nuclear medicine imaging and therapy

Winthrop, M. D., Denardo, G. L. & Denardo, S. J., 2000, In : Quarterly Journal of Nuclear Medicine. 44, 3, p. 284-295 12 p.

Research output: Contribution to journalReview article

3 Scopus citations

A phase I study of 90Y-2IT-BAD-Lym-1 in patients with non-Hodgkin's lymphoma

O'Donnell, R. T., Shen, S., Denardo, S. J., Wun, T., Kukis, D. L., Goldstein, D. S. & Denardo, G. L., 2000, In : Anticancer Research. 20, 5 C, p. 3647-3655 9 p.

Research output: Contribution to journalArticle

39 Scopus citations

Are Radiometal-Labeled Antibodies Better Than Iodine-131-Labeled Antibodies: Comparative Pharmacokinetics and Dosimetry of Copper-67-, Iodine-131-, and Yttrium-90-Labeled Lym-1 Antibody in Patients with Non-Hodgkin's Lymphoma

Denardo, G. L., DeNardo, S. J., O'Donnell, R. T., Kroger, L. A., Kukis, D. L., Meares, C. F., Goldstein, D. S. & Shen, S., Sep 2000, In : Clinical Lymphoma. 1, 2, p. 118-126 9 p.

Research output: Contribution to journalArticle

33 Scopus citations

Banner millennium 2000 year for CB&R and Mary Ann Liebert

Denardo, G. L. & Oldham, R. K., 2000, In : Cancer Biotherapy and Radiopharmaceuticals. 15, 6, p. 527-528 2 p.

Research output: Contribution to journalEditorial

Efficacy and toxicity of radioimmunotherapy with 90Y-DOTA-peptide-ChL6 for PC3-tumored mice

O'Donnell, R. T., DeNardo, S. J., Denardo, G. L., Miers, L., Lamborn, K. R., Kukis, D. L. & Meyers, F. J., Aug 1 2000, In : Prostate. 44, 3, p. 187-192 6 p.

Research output: Contribution to journalArticle

10 Scopus citations

Neovascular targeting with cyclic RGD peptide (cRGDf-ACHA) to enhance delivery of radioimmunotherapy

DeNardo, S. J., Burke, P. A., Leigh, B. R., O'Donnell, R. T., Miers, L. A., Kroger, L. A., Goodman, S. L., Matzku, S., Jonczyk, A., Lamborn, K. R. & Denardo, G. L., 2000, In : Cancer Biotherapy and Radiopharmaceuticals. 15, 1, p. 71-79 9 p.

Research output: Contribution to journalArticle

51 Scopus citations

Radiation dosimetry for 90Y-2IT-BAD-Lym-1 extrapolated from pharmacokinetics using 111In-2IT-BAD-Lym-1 in patients with non-Hodgkin's lymphoma

DeNardo, G. L., O'Donnell, R. T., Shen, S., Kroger, L. A., Yuan, A., Meares, C. F., Kukis, D. L. & DeNardo, S. J., May 2000, In : Journal of Nuclear Medicine. 41, 5, p. 952-958 7 p.

Research output: Contribution to journalArticle

35 Scopus citations

Radioimmunotherapy in the treatment of non-hodgkin’s Lymphoma

Krieger, M. S., Weiden, P. L., Breitz, H. B., Press, O. & Denardo, G. L., Jan 1 2000, Radioimmunotherapy of Cancer. CRC Press, p. 245-263 19 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Scopus citations
5 Scopus citations
1999

67Copper-2-iminothiolane-6-[p-(bromoacetamido)benzyl]-TETA-Lym-1 for radioimmunotherapy of non-Hodgkin's lymphoma

O'Donnell, R. T., Denardo, G. L., Kukis, D. L., Lamborn, K. R., Shen, S., Yuan, A., Goldstein, D. S., Mirick, G. R. & DeNardo, S. J., Oct 1999, In : Clinical Cancer Research. 5, 10 SUPPL.

Research output: Contribution to journalArticle

46 Scopus citations

67Cu-2IT-BAT-Lym-1 pharmacokinetics, radiation dosimetry, toxicity and tumor regression in patients with lymphoma

DeNardo, S. J., DeNardo, G. L., Kukis, D. L., Shen, S., Kroger, L. A., Denardo, D. A., Goldstein, D. S., Mirick, G. R., Salako, Q., Mausner, L. F., Srivastava, S. C. & Meares, C. F., Feb 1999, In : Journal of Nuclear Medicine. 40, 2, p. 302-310 9 p.

Research output: Contribution to journalArticle

70 Scopus citations

67Cu- versus 131I-labeled Lym-1 antibody: Comparative pharmacokinetics and dosimetry in patients with non-Hodgkin's lymphoma

Denardo, G. L., Kukis, D. L., Shen, S., DeNardo, D. A., Meares, C. F. & DeNardo, S. J., Mar 1999, In : Clinical Cancer Research. 5, 3, p. 533-541 9 p.

Research output: Contribution to journalArticle

70 Scopus citations

A clinical trial of radioimmunotherapy with 67Cu-2IT-BAT-Lym-1 for Non-Hodgkin's lymphoma

O'Donnell, R. T., Denardo, G. L., Kukis, D. L., Lamborn, K. R., Shen, S., Yuan, A., Goldstein, D. S., Carr, C. E., Mirick, G. R. & DeNardo, S. J., Dec 1999, In : Journal of Nuclear Medicine. 40, 12, p. 2014-2020 7 p.

Research output: Contribution to journalArticle

84 Scopus citations

A new era for radiolabeled antibodies in cancer?

Denardo, S. J., Kroger, L. A. & Denardo, G. L., Oct 1 1999, In : Current Opinion in Immunology. 11, 5, p. 563-569 7 p.

Research output: Contribution to journalReview article

66 Scopus citations

Antibody phage libraries for the next generation of tumor targeting radioimmunotherapeutics

DeNardo, S. J., Denardo, G. L., DeNardo, D. G., Xiong, C. Y., Shi, X. B., Winthrop, M. D., Kroger, L. A. & Carter, P., Oct 1999, In : Clinical Cancer Research. 5, 10 SUPPL.

Research output: Contribution to journalArticle

17 Scopus citations

Critical Lym-1 binding residues on polymorphic HLA-DR molecules

Rose, L. M., Deng, C. T., Scott, S. L., Xiong, C. Y., Lamborn, K. R., Gumerlock, P. H., Denardo, G. L. & Meares, C. F., Aug 1999, In : Molecular Immunology. 36, 11-12, p. 789-797 9 p.

Research output: Contribution to journalArticle

22 Scopus citations

Determination of spleen size by scintigraphy

Silverman, S., Denardo, G. L. & Siegel, E., 1999, In : Cancer Biotherapy and Radiopharmaceuticals. 14, 5, p. 407-411 5 p.

Research output: Contribution to journalArticle

7 Scopus citations

Development of a hyperimmune anti-MUC-1 single chain antibody fragments phage display library for targeting breast cancer

Winthrop, M. D., DeNardo, S. J. & Denardo, G. L., Oct 1999, In : Clinical Cancer Research. 5, 10 SUPPL.

Research output: Contribution to journalArticle

27 Scopus citations

Dosimetry-based therapy in metastatic breast cancer patients using 90Y monoclonal antibody 170H.82 with autologous stem cell support and cyclosporin A

Richman, C. M., DeNardo, S. J., O'Donnell, R. T., Goldstein, D. S., Shen, S., Kukis, D. L., Kroger, L. A., Yuan, A., Boniface, G. R., Griffith, I. J. & Denardo, G. L., Oct 1999, In : Clinical Cancer Research. 5, 10 SUPPL.

Research output: Contribution to journalArticle

41 Scopus citations

Dosimetry for radioimmunotherapy: A rapidly evolving field - Editorial

Wilder, R. B., Shen, S. & Denardo, G. L., 1999, In : Cancer Biotherapy and Radiopharmaceuticals. 14, 2, p. 67-70 4 p.

Research output: Contribution to journalEditorial

Effect of 67Cu-2IT-BAT-Lym-1 therapy on BCL-2 gene and protein expression in a lymphoma mouse model

Kroger, L. A., DeNardo, S. J., Denardo, G. L., Xiong, C. Y., Winthrop, M. D. & Gumerlock, P. H., Oct 1999, In : Clinical Cancer Research. 5, 10 SUPPL.

Research output: Contribution to journalArticle

11 Scopus citations

Efficient recombinant of Lym-1 scFv gene using multiple doubly- restricted DNA fragments

Shi, X. B., Gumerlock, P. H., Kroger, L., Denardo, G. L. & DeNardo, S. J., 1999, In : Cancer Biotherapy and Radiopharmaceuticals. 14, 2, p. 139-143 5 p.

Research output: Contribution to journalArticle

3 Scopus citations

Factors affecting 131I-Lym-1 pharmacokinetics and radiationdosimetry in patients with non-Hodgkin's lymphoma and chroniclymphocytic leukemia

Denardo, G. L., DeNardo, S. J., Shen, S., DeNardo, D. A., Mirick, G. R., Macey, D. J. & Lamborn, K. R., Aug 1999, In : Journal of Nuclear Medicine. 40, 8, p. 1317-1326 10 p.

Research output: Contribution to journalArticle

39 Scopus citations

'Historical vignettes': Editorial

DeNardo, G. L. & Oldham, R. K., 1999, In : Cancer Biotherapy and Radiopharmaceuticals. 14, 2, p. 65-66 2 p.

Research output: Contribution to journalEditorial

Milestones in the development of Lym-1 therapy

Denardo, G. L., O'Donnell, R. T., Rose, L. M., Mirick, G. R., Kroger, L. A. & DeNardo, S. J., Feb 1999, In : Hybridoma. 18, 1, p. 1-11 11 p.

Research output: Contribution to journalArticle

25 Scopus citations

Phage library-derived human anti-TETA and anti-DOTA scFv for pretargeting RIT

DeNardo, S. J., Denardo, G. L., Brush, J. & Carter, P., Feb 1999, In : Hybridoma. 18, 1, p. 13-21 9 p.

Research output: Contribution to journalArticle

16 Scopus citations

Planar gamma camera quantitation of 123I, 99mTc or 111In in the liver and spleen of an abdominal phantom

Macey, D. J., Denardo, G. L. & DeNardo, S. J., 1999, In : Cancer Biotherapy and Radiopharmaceuticals. 14, 4, p. 299-306 8 p.

Research output: Contribution to journalArticle

3 Scopus citations

Practical determination of patient-specific marrow dose using radioactivity concentration in blood and body

Shen, S., DeNardo, G. L., Sgouros, G., O'Donnell, R. T. & DeNardo, S. J., Dec 1999, In : Journal of Nuclear Medicine. 40, 12, p. 2102-2106 5 p.

Research output: Contribution to journalArticle

61 Scopus citations

Preclinical evaluation of chimeric L6 antibody for the treatment of Kaposi's sarcoma with radioimmunotherapy

Leigh, B. R., Burke, P. A., Hong, A. M., O'Donnell, R. T., Howell, L. P., Miers, L. A., Denardo, G. L. & DeNardo, S. J., 1999, In : Cancer Biotherapy and Radiopharmaceuticals. 14, 2, p. 113-119 7 p.

Research output: Contribution to journalArticle

4 Scopus citations

Radioimmunotherapy of acquired immunodeficiency syndrome (AIDS) associated lymphoma

O'Donnell, R. T., Leigh, B. R., Christensen, S. D., Goldstein, D. S., Kukis, D. L., Shen, S., Yuan, A., DeNardo, D. A., Kroger, L. A. & Denardo, G. L., 1999, In : Cancer Biotherapy and Radiopharmaceuticals. 14, 3, p. 167-176 10 p.

Research output: Contribution to journalArticle

4 Scopus citations

Stability of monoclonal antibodies, Lym-1 and ChL6, and 2IT-BAD-Lym-1 immunoconjugate with ultra freezer storage

Kukis, D. L., DeNardo, S. J., Mills, S. L., Shen, S., O'Donnell, R. T. & Denardo, G. L., 1999, In : Cancer Biotherapy and Radiopharmaceuticals. 14, 5, p. 363-369 7 p.

Research output: Contribution to journalArticle

4 Scopus citations

Strategies for developing effective radioimmunotherapy for solid tumors

Denardo, G. L., O'Donnell, R. T., Kroger, L. A., Richman, C. M., Goldstein, D. S., Shen, S. & DeNardo, S. J., Oct 1999, In : Clinical Cancer Research. 5, 10 SUPPL.

Research output: Contribution to journalArticle

26 Scopus citations

Transfer of copper from a chelated 67Cu-antibody conjugate to ceruloplasmin in lymphoma patients

Mirick, G. R., O'Donnell, R. T., Denardo, S. J., Shen, S., Meares, C. F. & Denardo, G. L., Oct 1999, In : Nuclear Medicine and Biology. 26, 7, p. 841-845 5 p.

Research output: Contribution to journalArticle

56 Scopus citations
1998

A preliminary cell kinetics model of thrombocytopenia after radioimmunotherapy

Shen, S., DeNardo, G. L., Jones, T. D., Wilder, R. B., O'Donnell, R. T. & DeNardo, S. J., Jul 1998, In : Journal of Nuclear Medicine. 39, 7, p. 1223-1229 7 p.

Research output: Contribution to journalArticle

11 Scopus citations

A revolution in the treatment of non-Hodgkin's lymphoma

DeNardo, G. L., O'Donnell, R. T., Oldham, R. K. & DeNardo, S. J., 1998, In : Cancer Biotherapy and Radiopharmaceuticals. 13, 4, p. 213-223 11 p.

Research output: Contribution to journalArticle

38 Scopus citations

Bone pain palliation

DeNardo, G. L., 1998, In : Cancer Biotherapy and Radiopharmaceuticals. 13, 6, p. 407-477 71 p.

Research output: Contribution to journalReview article

9 Scopus citations

Cancer Biotherapy and Radiopharmaceuticals: Editorial

DeNardo, G. L. & Oldham, R. K., 1998, In : Cancer Biotherapy and Radiopharmaceuticals. 13, 4, p. 211 1 p.

Research output: Contribution to journalEditorial

Cancer Biotherapy and Radiopharmaceuticals: Editorial

DeNardo, G. L., 1998, In : Cancer Biotherapy and Radiopharmaceuticals. 13, 5, p. 335-336 2 p.

Research output: Contribution to journalEditorial

1 Scopus citations

Combined modality radioimmunotherapy with taxol and 90Y-Lym-1 for Raji lymphoma xenografts

O'Donnell, R. T., DeNardo, S. J., Miers, L. A., Kukis, D. L., Mirick, G. R., Kroger, L. A. & Denardo, G. L., 1998, In : Cancer Biotherapy and Radiopharmaceuticals. 13, 5, p. 351-361 11 p.

Research output: Contribution to journalArticle

26 Scopus citations

Comparison of 1,4,7,10-tetraazacyclododecane-N,N',N'',N'''tetraacetic acid (DOTA)-peptide-ChL6, a novel immunoconjugate with catabolizable linker, to 2-iminothiolane-2[p-(bromoacetamido)benzyl]-DOTA-ChL6 in breast cancer xenografts

Denardo, G. L., Kroger, L. A., Meares, C. F., Richman, C. M., Salako, Q., Shen, S., Lamborn, K. R., Peterson, J. J., Miers, L. A., Zhong, G. R. & DeNardo, S. J., Oct 1998, In : Clinical Cancer Research. 4, 10, p. 2483-2490 8 p.

Research output: Contribution to journalArticle

26 Scopus citations

L6 monoclonal antibody binds prostate cancer

O'Donnell, R. T., DeNardo, S. J., Shi, X. B., Mirick, G. R., Denardo, G. L., Kroger, L. A. & Meyers, F. J., Oct 1 1998, In : Prostate. 37, 2, p. 91-97 7 p.

Research output: Contribution to journalArticle

22 Scopus citations

Low-dose, fractionated radioimmunotherapy for B-cell malignancies using 131I-LYM-1 antibody

Denardo, G. L., DeNardo, S. J., Lamborn, K. R., Goldstein, D. S., Levy, N. B., Lewis, J. P., O'Grady, L. F., Raventos, A., Kroger, L. A., Macey, D. J., McGahan, J. P., Mills, S. L. & Shen, S., 1998, In : Cancer Biotherapy and Radiopharmaceuticals. 13, 4, p. 239-254 16 p.

Research output: Contribution to journalArticle

99 Scopus citations

Maximum-tolerated dose, toxicity, and efficacy of 131I-Lym-1 antibody for fractionated radioimmunotherapy of non-Hodgkin's lymphoma

Denardo, G. L., DeNardo, S. J., Goldstein, D. S., Kroger, L. A., Lamborn, K. R., Levy, N. B., McGahan, J. P., Salako, Q., Shen, S. & Lewis, J. P., Oct 1998, In : Journal of Clinical Oncology. 16, 10, p. 3246-3256 11 p.

Research output: Contribution to journalArticle

189 Scopus citations

Maximum tolerated dose of 67Cu-2IT-BAT-LYM-1 for fractionated radioimmunotherapy of non-Hodgkin's lymphoma: A pilot study

Denardo, G. L., Denardo, S. J., Kukis, D. L., O'Donnell, R. T., Shen, S., Goldstein, D. S., Kroger, L. A., Salako, Q., Denardo, D. A., Mirick, G. R., Mausner, L. F., Srivastava, S. C. & Meares, C. F., Jul 1998, In : Anticancer Research. 18, 4 B, p. 2779-2788 10 p.

Research output: Contribution to journalArticle

65 Scopus citations

New anti-Cu-TETA and anti-Y-DOTA monoclonal antibodies for potential use in the pre-targeted delivery of radiopharmaceuticals to tumor

Feng, X., Pak, R. H., Kroger, L. A., Moran, J. K., DeNardo, D. G., Meares, C. F., Denardo, G. L. & DeNardo, S. J., 1998, In : Hybridoma. 17, 2, p. 125-132 8 p.

Research output: Contribution to journalArticle

25 Scopus citations

Optimized conditions for chelation of yttrium-90-DOTA immunoconjugates

Kukis, D. L., DeNardo, S. J., DeNardo, G. L., O'Donnell, R. T. & Meares, C. F., Dec 1998, In : Journal of Nuclear Medicine. 39, 12, p. 2105-2110 6 p.

Research output: Contribution to journalArticle

73 Scopus citations

Prolonged survival associated with immune response in a patient treated with Lym-1 mouse monoclonal antibody

DeNardo, S. J., Kroger, L. A., MacKenzie, M. R., Mirick, G. R., Shen, S. & Denardo, G. L., Feb 1998, In : Cancer Biotherapy and Radiopharmaceuticals. 13, 1, p. 1-12 12 p.

Research output: Contribution to journalArticle

17 Scopus citations

Quantification of iodine-131 in tumors using a threshold based on image contrast

Denardo, G. L., Shen, S., DeNardo, S. J., Liao, S. Q., Lamborn, K. R., DeNardo, D. A. & Yuan, A., 1998, In : European Journal Of Nuclear Medicine. 25, 5, p. 497-502 6 p.

Research output: Contribution to journalArticle

13 Scopus citations