Gerald L Denardo

Professor Emeritus

  • 8492 Citations
  • 51 h-Index
1962 …2018

Research output per year

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Research Output

2005

Application of high amplitude alternating magnetic fields for heat induction of nanoparticles localized in cancer

Ivkov, R., DeNardo, S. J., Daum, W., Foreman, A. R., Goldstein, R. C., Nemkov, V. S. & Denardo, G. L., Oct 1 2005, In : Clinical Cancer Research. 11, 19 II

Research output: Contribution to journalArticle

145 Scopus citations

Characterization of site-specific ScFv PEGylation for tumor-targeting pharmaceuticals

Natarajan, A., Xiong, C. Y., Albrecht, H., Denardo, G. L. & DeNardo, S. J., Jan 2005, In : Bioconjugate Chemistry. 16, 1, p. 113-121 9 p.

Research output: Contribution to journalArticle

53 Scopus citations
19 Scopus citations

Development of tumor targeting bioprobes (111In-chimeric L6 monoclonal antibody nanoparticles) for alternating magnetic field cancer therapy

DeNardo, S. J., Denardo, G. L., Miers, L. A., Natarajan, A., Foreman, A. R., Gruettner, C., Adamson, G. N. & Ivkov, R., Oct 1 2005, In : Clinical Cancer Research. 11, 19 II

Research output: Contribution to journalArticle

170 Scopus citations

Direct antilymphoma effects on human lymphoma cells of monotherapy and combination therapy with CD20 and HLA-DR antibodies and 90Y-labeled HLA-DR antibodies

Denardo, G. L., Tobin, E., Chan, K., Bradt, B. M. & DeNardo, S. J., Oct 1 2005, In : Clinical Cancer Research. 11, 19 II

Research output: Contribution to journalArticle

22 Scopus citations

Does paclitaxel (taxol) given after111In-labeled monoclonal antibodies increase tumor-cumulated activity in epithelial cancers?

Miers, L., Lamborn, K., Yuan, A., Richman, C. M., Natarajan, A., DeNardo, S. & Denardo, G. L., Oct 1 2005, In : Clinical Cancer Research. 11, 19 II

Research output: Contribution to journalArticle

8 Scopus citations

Enhancement of the therapeutic index: From nonmyeloablative and myeloablative toward pretargeted radioimmunotherapy for metastatic prostate cancer

DeNardo, S. J., Richman, C. M., Albrecht, H., Burke, P. A., Natarajan, A., Yuan, A., Gregg, J., O'Donnell, R. T. & Denardo, G. L., Oct 1 2005, In : Clinical Cancer Research. 11, 19 II

Research output: Contribution to journalArticle

25 Scopus citations
67 Scopus citations

Implantation of different malignant human cell lines in an athymic mouse does not alter success and growth rates of either xenograft

Miers, L., DeNardo, S. J., Lamborn, K. & Denardo, G. L., 2005, In : Cancer Biotherapy and Radiopharmaceuticals. 20, 6, p. 614-619 6 p.

Research output: Contribution to journalArticle

MINERVA: A multi-modality plugin-based radiation therapy treatment planning system

Wemple, C. A., Wessol, D. E., Nigg, D. W., Cogliati, J. J., Milvich, M., Fredrickson, C. M., Perkins, M., Harkin, G. J., Hartmann-Siantar, C. L., Lehmann, J., Flickinger, T., Pletcher, D., Yuan, A. & DeNardo, G. L., Dec 20 2005, In : Radiation Protection Dosimetry. 116, 1-4, p. 202-207 6 p.

Research output: Contribution to journalArticle

3 Scopus citations

Monte Carlo treatment planning for molecular targeted radiotherapy within the MINERVA system

Lehmann, J., Siantar, C. H., Wessol, D. E., Wemple, C. A., Nigg, D., Cogliati, J., Daly, T., Descalle, M. A., Flickinger, T., Pletcher, D. & DeNardo, G., Mar 7 2005, In : Physics in Medicine and Biology. 50, 5, p. 947-958 12 p.

Research output: Contribution to journalArticle

21 Scopus citations

Planning time for peripheral blood stem cell infusion after high-dose targeted radionuclide therapy using dosimetry

Shen, S., DeNardo, S. J., Richman, C. M., Yuan, A., Siantar, C. H., O'Donnell, R. T., Kroger, L. A. & Denardo, G. L., 2005, In : Journal of Nuclear Medicine. 46, 6, p. 1034-1041 8 p.

Research output: Contribution to journalArticle

6 Scopus citations

Splenic volume change and nodal tumor response in non-Hodgkin's lymphoma patients after radioimmunotherapy using radiolabeled Lym-1 antibody

Shen, S., Denardo, G. L., Yuan, A., Hartmann-Siantar, C., O'Donnell, R. T. & DeNardo, S. J., 2005, In : Cancer Biotherapy and Radiopharmaceuticals. 20, 6, p. 662-670 9 p.

Research output: Contribution to journalArticle

8 Scopus citations

Treatment of Non-Hodgkin's Lymphoma (NHL) with radiolabeled antibodies (mAbs)

Denardo, G. L., Jul 2005, In : Seminars in Nuclear Medicine. 35, 3 SPEC. ISS., p. 202-211 10 p.

Research output: Contribution to journalArticle

29 Scopus citations
2004

Antilymphoma effects of anti-HLA-DR and CD20 monoclonal antibodies (Lym-1 and rituximab) on human lymphoma cells

Liu, C., Denardo, G. L., Tobin, E. & DeNardo, S., 2004, In : Cancer Biotherapy and Radiopharmaceuticals. 19, 5, p. 545-561 17 p.

Research output: Contribution to journalArticle

22 Scopus citations

A review of human anti-globulin antibody (HAGA, HAMA, HACA, HAHA) responses to monoclonal antibodies not four letter words

Mirick, G. R., Bradt, B. M., Denardo, S. J. & Denardo, G. L., 2004, In : Quarterly Journal of Nuclear Medicine and Molecular Imaging. 48, 4, p. 251-257 7 p.

Research output: Contribution to journalReview article

84 Scopus citations

Bone marrow dosimetry using blood-based models for radiolabeled antibody therapy: A multiinstitutional comparison

Wessels, B. W., Bolch, W. E., Bouchet, L. G., Breitz, H. B., Denardo, G. L., Meredith, R. F., Stabin, M. G. & Sgouros, G., Oct 1 2004, In : Journal of Nuclear Medicine. 45, 10, p. 1725-1733 9 p.

Research output: Contribution to journalArticle

49 Scopus citations
10 Scopus citations

MINERVA: A multimodality plugin-based radiation therapy treatment planning system

Wemple, C. A., Wessol, D. E., Nigg, D. W., Cogliati, J. J., Milvich, M., Fredrickson, C. M., Perkins, M., Harkin, G. J., Hartmann-Siantar, C. L., Lehmann, J., Flickinger, T., Pletcher, D., Yuan, A. & DeNardo, G. L., 2004, Transactions of the American Nuclear Society. Folkerts, D. K. (ed.). Vol. 91. p. 683-685 3 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

New directions in radioimmunotherapy on non-Hodgkin's lymphoma

Denardo, G. L., Oct 2004, In : Clinical Lymphoma. 5, SUPPL. 1

Research output: Contribution to journalEditorial

1 Scopus citations

Production of Soluble ScFvs with C-Terminal-Free Thiol for Site-Specific Conjugation or Stable Dimeric ScFvs on Demand

Albrecht, H., Burke, P. A., Natarajan, A., Xiong, C. Y., Kalicinsky, M., Denardo, G. L. & DeNardo, S. J., Jan 2004, In : Bioconjugate Chemistry. 15, 1, p. 16-26 11 p.

Research output: Contribution to journalArticle

52 Scopus citations

Radiometals as payloads for radioimmunotherapy for lymphoma

Denardo, G. L., Kennel, S. J., Siegel, J. A. & DeNardo, S. J., Oct 2004, In : Clinical Lymphoma. 5, SUPPL. 1

Research output: Contribution to journalArticle

17 Scopus citations
2003

Anti-CD22 ligand-blocking antibody HB22.7 has independent lymphomacidal properties and augments the efficacy of 90Y-DOTA-peptide-Lym-1 in lymphoma xenografts

Tuscano, J. M., O'Donnell, R. T., Miers, L. A., Kroger, L. A., Kukis, D. L., Lamborn, K. R., Tedder, T. F. & DeNardo, G. L., May 1 2003, In : Blood. 101, 9, p. 3641-3647 7 p.

Research output: Contribution to journalArticle

44 Scopus citations

Application of MINERVA Monte Carlo simulations to targeted radionuclide therapy

Descalle, M. A., Hartmann Siantar, C. L., Dauffy, L., Nigg, D. W., Wemple, C. A., Yuan, A. & Denardo, G. L., 2003, In : Cancer Biotherapy and Radiopharmaceuticals. 18, 1, p. 71-79 9 p.

Research output: Contribution to journalArticle

18 Scopus citations

Characterization of human IgG antimouse antibody in patients with B-cell malignancies

Denardo, G. L., Mirick, G. R., Kroger, L. A., Bradt, B. M., Lamborn, K. R. & DeNardo, S. J., Oct 1 2003, In : Clinical Cancer Research. 9, 10 II

Research output: Contribution to journalArticle

11 Scopus citations

Documentation of idiotypic cascade after Lym-1 radioimmunotherapy in a patient with non-Hodgkin's lymphoma: Basis for extended survival?

Bradt, B. M., DeNardo, S. J., Mirick, G. R. & Denardo, G. L., Oct 1 2003, In : Clinical Cancer Research. 9, 10 II

Research output: Contribution to journalArticle

10 Scopus citations

Effect of molecular size of pegylated peptide on the pharmacokinetics and tumor targeting in lymphoma-bearing mice

DeNardo, S. J., Yao, Z., Lam, K., Song, A., Burke, P. A., Mirick, G. R., Lamborn, K. R., O'Donnell, R. T. & Denardo, G. L., Oct 1 2003, In : Clinical Cancer Research. 9, 10 II

Research output: Contribution to journalArticle

34 Scopus citations
25 Scopus citations

Human antiglobulin response to foreign antibodies: Therapeutic benefit?

Denardo, G. L., Bradt, B. M., Mirick, G. R. & DeNardo, S. J., May 1 2003, In : Cancer Immunology, Immunotherapy. 52, 5, p. 309-316 8 p.

Research output: Contribution to journalArticle

46 Scopus citations

Impact of interpatient pharmacokinetic variability on design considerations for therapy with radiolabeled MAbs

Denardo, G. L., Yuan, A., Goldstein, D., Richman, C. M., O'Donnell, R. T., Shen, S., Hartmann Siantar, C. & DeNardo, S., 2003, In : Cancer Biotherapy and Radiopharmaceuticals. 18, 2, p. 231-237 7 p.

Research output: Contribution to journalArticle

8 Scopus citations

Impact of nodal regression on radiation dose for lymphoma patients after radioimmunotherapy

Siantar, C. L. H., Denardo, G. L. & DeNardo, S. J., Aug 2003, In : Journal of Nuclear Medicine. 44, 8, p. 1322-1329 8 p.

Research output: Contribution to journalArticle

11 Scopus citations

Preclinical evaluation of cathepsin-degradable peptide linkers for radioimmunoconjugates

Denardo, G. L., DeNardo, S. J., Peterson, J. J., Miers, L. A., Lam, K., Hartmann-Siantar, C. & Lamborn, K. R., Oct 1 2003, In : Clinical Cancer Research. 9, 10 II

Research output: Contribution to journalArticle

18 Scopus citations

Radioimmunotherapy: A Novel Treatment Modality for B-Cell Non-Hodgkin's Lymphoma

Juweid, M., Denardo, G. L., Graham, M. & Vose, J., 2003, In : Cancer Biotherapy and Radiopharmaceuticals. 18, 5, p. 673-674 2 p.

Research output: Contribution to journalEditorial

9 Scopus citations

Selection and characterization of anti-MUC-1 scFvs intended for targeted therapy

Winthrop, M. D., DeNardo, S. J., Albrecht, H., Mirick, G. R., Kroger, L. A., Lamborn, K. R., Venclovas, Ç., Colvin, M. E., Burke, P. A. & Denardo, G. L., Oct 1 2003, In : Clinical Cancer Research. 9, 10 II

Research output: Contribution to journalArticle

20 Scopus citations
2002

Cilengitide targeting of αvβ3 integrin receptor synergizes with radioimmunotherapy to increase efficacy and apoptosis in breast cancer xenografts

Burke, P. A., DeNardo, S. J., Miers, L. A., Lamborn, K. R., Matzku, S. & Denardo, G. L., Aug 1 2002, In : Cancer Research. 62, 15, p. 4263-4272 10 p.

Research output: Contribution to journalArticle

210 Scopus citations

Combined modality radioimmunotherapy: Promise and peril

Burke, P. A., DeNardo, S. J., Miers, L. A., Kukis, D. L. & Denardo, G. L., Feb 15 2002, In : Cancer. 94, 4 SUPPL., p. 1320-1331 12 p.

Research output: Contribution to journalArticle

43 Scopus citations

Combined modality radioimmunotherapy for human prostate cancer xenografts with taxanes and 90Yttrium-DOTA-peptide-ChL6

O'Donnell, R. T., Denardo, S. J., Miers, L. A., Lamborn, K. R., Kukis, D. L., Denardo, G. L. & Meyers, F. J., Jan 1 2002, In : Prostate. 50, 1, p. 27-37 11 p.

Research output: Contribution to journalArticle

59 Scopus citations

Radiation dosimetry for radionuclide therapy in a nonmyeloablative strategy

Denardo, G. L., Hartmann Siantar, C. L. & DeNardo, S. J., 2002, In : Cancer Biotherapy and Radiopharmaceuticals. 17, 1, p. 107-118 12 p.

Research output: Contribution to journalArticle

16 Scopus citations

Rationales, evidence, and design considerations for fractionated radioimmunotherapy

Denardo, G. L., Schlom, J., Buchsbaum, D. J., Meredith, R. F., O'Donoghue, J. A., Sgouros, G., Humm, J. L. & DeNardo, S. J., Feb 15 2002, In : Cancer. 94, 4 SUPPL., p. 1332-1348 17 p.

Research output: Contribution to journalArticle

100 Scopus citations

Treatment planning for molecular targeted radionuclide therapy

Hartmann Siantar, C. L., Vetter, K., Denardo, G. L. & DeNardo, S. J., 2002, In : Cancer Biotherapy and Radiopharmaceuticals. 17, 3, p. 267-280 14 p.

Research output: Contribution to journalReview article

13 Scopus citations

Year 2002: The best year yet for CB & R

Denardo, G. L. & Oldham, R. K., 2002, In : Cancer Biotherapy and Radiopharmaceuticals. 17, 6, p. 599-600 2 p.

Research output: Contribution to journalEditorial

2001

Anti-HLA-DR/anti-DOTA diabody construction in a modular gene design platform: Bispecific antibodies for pretargeted radioimmunotherapy

DeNardo, D. G., Xiong, C. Y., Shi, X. B., Denardo, G. L. & DeNardo, S. J., 2001, In : Cancer Biotherapy and Radiopharmaceuticals. 16, 6, p. 525-535 11 p.

Research output: Contribution to journalArticle

24 Scopus citations

Apoptosis-related gene and protein expression in human lymphoma xenografts (Raji) after low dose rate radiation using 67Cu-2IT-BAT-Lym-1 radioimmunotherapy

Kroger, L. A., Denardo, G. L., Gumerlock, P. H., Cheng Yi Xiong, Y. X., Winthrop, M. D., Xu Bao Shi, B. S., Mack, P., Leshchinsky, T. & Denardo, S. J., 2001, In : Cancer Biotherapy and Radiopharmaceuticals. 16, 3, p. 213-225 13 p.

Research output: Contribution to journalArticle

45 Scopus citations

Cancer Biotherapy and Radiopharmaceuticals: Editorial

Denardo, G. L., 2001, In : Cancer Biotherapy and Radiopharmaceuticals. 16, 5, p. 345 1 p.

Research output: Contribution to journalEditorial

Metabolite production in patients with lymphoma after radiometal-labeled antibody administration

Denardo, G. L., DeNardo, S. J., Kukis, D. L., O'Donnell, R. T., Shen, S., Mirick, G. R. & Meares, C. F., 2001, In : Journal of Nuclear Medicine. 42, 9, p. 1324-1333 10 p.

Research output: Contribution to journalArticle

3 Scopus citations

Radioimmunotherapy with 111In/90Y-2IT-BAD-m170 for metastatic prostate cancer

O'Donnell, R. T., DeNardo, S. J., Yuan, A., Shen, S., Richman, C. M., Lara, P. N., Griffith, I. J., Goldstein, D. S., Kukis, D. L., Martinez, G. S., Mirick, G. R., Denardo, G. L. & Meyers, F. J., 2001, In : Clinical Cancer Research. 7, 6, p. 1561-1568 8 p.

Research output: Contribution to journalArticle

52 Scopus citations

Radiolabeled anti-lymphoma antibodies.

Denardo, G. L., O'Donnell, R. T. & DeNardo, S. J., 2001, In : Cancer chemotherapy and biological response modifiers. 19, p. 297-308 12 p.

Research output: Contribution to journalArticle

5 Scopus citations

Role of radiation dosimetry in radioimmunotherapy planning and treatment dosing

Denardo, G. L., Juweid, M. E., White, C. A., Wiseman, G. A. & DeNardo, S. J., 2001, In : Critical Reviews in Oncology/Hematology. 39, 1-2, p. 203-218 16 p.

Research output: Contribution to journalArticle

23 Scopus citations

Year 2001: An even better year for CB&R

Denardo, G. L. & Oldham, R. K., Dec 1 2001, In : Cancer Biotherapy and Radiopharmaceuticals. 16, 6, p. 449-450 2 p.

Research output: Contribution to journalEditorial

2000

131I-Lym-1 in mice implanted with human Burkitt's lymphoma (Raji) tumors: Loss of tumor specificity due to radiolysis

Denardo, G. L., DeNardo, S. J., Wessels, B. W., Kukis, D. L., Miyao, N. & Yuan, A., 2000, In : Cancer Biotherapy and Radiopharmaceuticals. 15, 6, p. 547-560 14 p.

Research output: Contribution to journalArticle

13 Scopus citations