Fredric A Gorin, MD; PhD

Professor

  • 1808 Citations
  • 24 h-Index
1972 …2018

Research output per year

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Research Output

  • 1808 Citations
  • 24 h-Index
  • 65 Article
  • 1 Chapter
  • 1 Conference contribution
  • 1 Review article
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Article
2018

In Vivo MRI of Functionalized Iron Oxide Nanoparticles for Brain Inflammation

Tang, T., Valenzuela, A., Petit, F., Chow, S., Leung, K., Gorin, F. A., Louie, A. Y. & Dhenain, M., Jan 1 2018, In : Contrast Media and Molecular Imaging. 2018, 3476476.

Research output: Contribution to journalArticle

5 Scopus citations

Label-free fluorescence lifetime spectroscopy detects radiation-induced necrotic changes in live brain in real-time

Hartl, B. A., Ma, H. S. W., Sridharan, S., Hansen, K. S., Kent, M. S., Gorin, F., Fragoso, R. C. & Marcu, L., Aug 1 2018, In : Biomedical Optics Express. 9, 8, p. 3559-3580 22 p., 323491.

Research output: Contribution to journalArticle

1 Scopus citations
2015
6 Scopus citations

Mis-trafficking of endosomal urokinase proteins triggers drug-induced glioma nonapoptotic cell death

Pasupuleti, N., Grodzki, A. & Gorin, F. A., 2015, In : Molecular Pharmacology. 87, 4, p. 683-696 14 p.

Research output: Contribution to journalArticle

6 Scopus citations
2013
30 Scopus citations

A Cell-Permeant Amiloride Derivative Induces Caspase-Independent, AIF-Mediated Programmed Necrotic Death of Breast Cancer Cells

Leon, L. J., Pasupuleti, N., Gorin, F. A. & Carraway, K. L., Apr 30 2013, In : PLoS One. 8, 4, e63038.

Research output: Contribution to journalArticle

16 Scopus citations

Size-stable solid lipid nanoparticles loaded with Gd-DOTA for magnetic resonance imaging

Andreozzi, E., Wang, P., Valenzuela, A., Tu, C., Gorin, F. A., Dhenain, M. & Louie, A., Sep 18 2013, In : Bioconjugate Chemistry. 24, 9, p. 1455-1467 13 p.

Research output: Contribution to journalArticle

16 Scopus citations
2012

2-Amidino analogs of glycine-amiloride conjugates: Inhibitors of urokinase-type plasminogen activator

Massey, A. P., Harley, W. R., Pasupuleti, N., Gorin, F. A. & Nantz, M. H., Apr 1 2012, In : Bioorganic and Medicinal Chemistry Letters. 22, 7, p. 2635-2639 5 p.

Research output: Contribution to journalArticle

4 Scopus citations
2010

Dual inhibition of sodium-mediated proton and calcium efflux triggers non-apoptotic cell death in malignant gliomas

Harley, W., Floyd, C., Dunn, T., Zhang, X. D., Chen, T. Y., Hegde, M., Palandoken, H., Nantz, M. H., Leon, L., Carraway, K. L., Lyeth, B. & Gorin, F. A., Dec 6 2010, In : Brain Research. 1363, p. 159-169 11 p.

Research output: Contribution to journalArticle

24 Scopus citations

Fluorescence lifetime imaging microscopy for brain tumor image-guided surgery

Sun, Y., Hatami, N., Yee, M., Phipps, J., Elson, D. S., Gorin, F. A., Schrot, R. J. & Marcu, L., Sep 2010, In : Journal of Biomedical Optics. 15, 5, 056022.

Research output: Contribution to journalArticle

97 Scopus citations
2008

An acidic environment changes cyclin D1 localization and alters colony forming ability in gliomas

Schnier, J. B., Nishi, K., Harley, W. R. & Gorin, F. A., Aug 2008, In : Journal of Neuro-Oncology. 89, 1, p. 19-26 8 p.

Research output: Contribution to journalArticle

6 Scopus citations
24 Scopus citations
2007

Dynamics of tyrosine hydroxylase mediated regulation of dopamine synthesis

Kaushik, P., Gorin, F. A. & Vali, S., Apr 2007, In : Journal of Computational Neuroscience. 22, 2, p. 147-160 14 p.

Research output: Contribution to journalArticle

42 Scopus citations

Integrating glutathione metabolism and mitochondrial dysfunction with implications for Parkinson's disease: A dynamic model

Vali, S., Mythri, R. B., Jagatha, B., Padiadpu, J., Ramanujan, K. S., Andersen, J. K., Gorin, F. A. & Bharath, M. M. S., Nov 23 2007, In : Neuroscience. 149, 4, p. 917-930 14 p.

Research output: Contribution to journalArticle

62 Scopus citations
2006

Dynamic modeling of alpha-synuclein aggregation for the sporadic and genetic forms of Parkinson's disease

Raichur, A., Vali, S. & Gorin, F. A., Oct 27 2006, In : Neuroscience. 142, 3, p. 859-870 12 p.

Research output: Contribution to journalArticle

29 Scopus citations
2005

Amiloride peptide conjugates: Prodrugs for sodium-proton exchange inhibition

Palandoken, H., By, K., Hegde, M., Harley, W. R., Gorin, F. A. & Nantz, M. H., Mar 2005, In : Journal of Pharmacology and Experimental Therapeutics. 312, 3, p. 961-967 7 p.

Research output: Contribution to journalArticle

13 Scopus citations

Comparison of vector space model methodologies to reconcile cross-species neuroanatomical concepts

Srinivas, P. R., Wei, S. H., Cristianini, N., Jones, E. G. & Gorin, F. A., 2005, In : Neuroinformatics. 3, 2, p. 115-131 17 p.

Research output: Contribution to journalArticle

2 Scopus citations

Glycogen synthesis correlates with androgen-dependent growth arrest in prostate cancer

Schnier, J. B., Nishi, K., Gumerlock, P. H., Gorin, F. A. & Bradbury, E. M., Mar 24 2005, In : BMC Urology. 5, 6.

Research output: Contribution to journalArticle

12 Scopus citations

Mechanical strain injury increases intracellular sodium and reverses Na+/Ca2+ exchange in cortical astrocytes

Floyd, C. L., Gorin, F. A. & Lyeth, B. G., Jul 2005, In : GLIA. 51, 1, p. 35-46 12 p.

Research output: Contribution to journalArticle

70 Scopus citations
2004
28 Scopus citations

Perinecrotic glioma proliferation and metabolic profile within an intracerebral tumor xenograft

Gorin, F. A., Harley, W., Schnier, J., Lyeth, B. G. & Jue, T., Mar 2004, In : Acta Neuropathologica. 107, 3, p. 235-244 10 p.

Research output: Contribution to journalArticle

32 Scopus citations
2003

Inhibition of glycogen phosphorylase (GP) by CP-91,149 induces growth inhibition correlating with brain GP expression

Schnier, J. B., Nishi, K., Monks, A., Gorin, F. A. & Bradbury, E. M., Sep 12 2003, In : Biochemical and Biophysical Research Communications. 309, 1, p. 126-134 9 p.

Research output: Contribution to journalArticle

42 Scopus citations

jTerm: an open source terminology server.

Hogarth, M. A., Gertz, M. & Gorin, F. A., 2003, In : AMIA ... Annual Symposium proceedings / AMIA Symposium. AMIA Symposium. p. 861 1 p.

Research output: Contribution to journalArticle

1 Scopus citations

Neuroanatomical term generation and comparison between two terminologies

Srinivas, P. R., Gusfield, D., Mason, O., Gertz, M., Hogarth, M., Stone, J., Jones, E. G. & Gorin, F. A., 2003, In : Neuroinformatics. 1, 2, p. 177-192 16 p.

Research output: Contribution to journalArticle

4 Scopus citations
2001

The challenges and rewards of integrating diverse neuroscience information

Gorin, F. A., Hogarth, M. & Gertz, M., 2001, In : Neuroscientist. 7, 1, p. 18-27 10 p.

Research output: Contribution to journalArticle

8 Scopus citations

The cyclin-dependent kinase (CDK) inhibitor flavopiridol inhibits glycogen phosphorylase

Kaiser, A., Nishi, K., Gorin, F. A., Walsh, D. A., Morton Bradbury, E. & Schnier, J. B., Feb 15 2001, In : Archives of Biochemistry and Biophysics. 386, 2, p. 179-187 9 p.

Research output: Contribution to journalArticle

57 Scopus citations
2000

Malignant gliomas display altered pH regulation by NHE1 compared with nontransformed astrocytes

McLean, L. A., Roscoe, J., Jørgensen, N. K., Gorin, F. A. & Cala, P. M., 2000, In : American Journal of Physiology - Cell Physiology. 278, 4 47-4

Research output: Contribution to journalArticle

146 Scopus citations
10 Scopus citations

Stretch-activated ion channels contribute to membrane depolarization after eccentric contractions

McBride, T. A., Stockert, B. W., Gorin, F. A. & Carlsen, R. C., Jan 2000, In : Journal of Applied Physiology. 88, 1, p. 91-101 11 p.

Research output: Contribution to journalArticle

82 Scopus citations

Terminology Query Language: a server interface for concept-oriented terminology systems.

Hogarth, M. A., Gertz, M. & Gorin, F. A., 2000, In : Proceedings / AMIA ... Annual Symposium. AMIA Symposium. p. 349-353 5 p.

Research output: Contribution to journalArticle

5 Scopus citations
1999
30 Scopus citations
1998

Asymptomatic McArdle's disease associated with hyper-creatine kinase- emia and absence of myophosphorylase

Gospe S.M., J., El-Schahawi, M., Shanske, S., Bruno, C., DiMauro, S., Hoye, E., Walsh, D. A. & Gorin, F. A., 1998, In : Neurology. 51, 4, p. 1228-1229 2 p.

Research output: Contribution to journalArticle

13 Scopus citations

Functional expression of amphiuma red blood cell NA+/H+ exchanger (NHE) in an NHE-deficient cell line

McLean, L. A., Zia, S., Roscoe, J., Jorgensen, N. K., Gorin, F. A. & Cala, P. M., Mar 20 1998, In : FASEB Journal. 12, 5

Research output: Contribution to journalArticle

Nerve-dependent factors regulating transcript levels of glycogen phosphorylase in skeletal muscle

Matthews, C. C., Carlsen, R. C., Froman, B., Tait, R. & Gorin, F. A., 1998, In : Cellular and Molecular Neurobiology. 18, 3, p. 319-338 20 p.

Research output: Contribution to journalArticle

6 Scopus citations

Role of E and CArG boxes in developmental regulation of muscle glycogen phosphorylase promoter during myogenesis

Froman, B. E., Tait, R. C. & Gorin, F. A., 1998, In : DNA and Cell Biology. 17, 2, p. 105-115 11 p.

Research output: Contribution to journalArticle

4 Scopus citations
1996

Botulinum-induced muscle paralysis alters metabolic gene expression and fatigue recovery

Gorin, F. A., Herrick, K., Froman, B., Palmer, W., Tait, R. & Carlsen, R., 1996, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 270, 1 39-1

Research output: Contribution to journalArticle

7 Scopus citations

Histochemical demonstration of glycogen in neurons of the cat retina.

Burns, M. S., Gorin, F. A., Anderson, K. & Nihira, M., Sep 1996, In : Investigative ophthalmology & visual science. 37, 10, p. 1937 1 p.

Research output: Contribution to journalArticle

1 Scopus citations

Regulation of intracellular ph in transformed glial cells vs. primary astrocytes

McLean, L. A., Roscoe, J., Tait, R., Gorin, F. A. & Gala, P. M., 1996, In : FASEB Journal. 10, 3

Research output: Contribution to journalArticle

1995

A subgroup of human VH3 germline genes that encode a high-avidity synovial rheumatoid factor

Wong, A., Tait, R., Kenny, T., Gorin, F. A. & Robbins, D., 1995, In : Autoimmunity. 20, 3, p. 191-199 9 p.

Research output: Contribution to journalArticle

2 Scopus citations

Primate rod and cone photoreceptors may differ in glucose accessibility

Nihira, M., Anderson, K., Gorin, F. A. & Burns, M. S., 1995, In : Investigative Ophthalmology and Visual Science. 36, 7, p. 1259-1270 12 p.

Research output: Contribution to journalArticle

44 Scopus citations

Prolonged recovery and reduced adaptation in aged rat muscle following eccentric exercise

McBride, T. A., Gorin, F. A. & Carlsen, R. C., Sep 15 1995, In : Mechanisms of Ageing and Development. 83, 3, p. 185-200 16 p.

Research output: Contribution to journalArticle

64 Scopus citations
1994

Regulation of the rat muscle glycogen phosphorylase-encoding gene during muscle cell development

Froman, B. E., Herrick, K. R. & Gorin, F. A., Nov 18 1994, In : Gene. 149, 2, p. 245-252 8 p.

Research output: Contribution to journalArticle

1993

Characterization of the 5' flanking region of the gene encoding rat liver glycogen phosphorylase

Herrick, K. R., Gorin, F. A., Park, E. A. & Tait, R. C., Apr 30 1993, In : Gene. 126, 2, p. 203-211 9 p.

Research output: Contribution to journalArticle

7 Scopus citations
1992

Coordinated expression of phosphorylase kinase subunits in regenerating skeletal muscle

Cawley, K. C., Akita, C. G., Wineinger, M. A., Carlsen, R. C., Gorin, F. A. & Walsh, D. A., Aug 25 1992, In : Journal of Biological Chemistry. 267, 24, p. 17287-17295 9 p.

Research output: Contribution to journalArticle

7 Scopus citations

M4 and M9 antibodies in the overlap syndrome of primary biliary cirrhosis and chronic active hepatitis: Epitopes or epiphenomena?

Davis, P. A., Leung, P. S., Manns, M., Kaplan, M., Munoz, S. J., Gorin, F. A., Dickson, E. R., Krawitt, E., Coppel, R. & Gershwin, M. E., Nov 1992, In : Hepatology. 16, 5, p. 1128-1136 9 p.

Research output: Contribution to journalArticle

67 Scopus citations
1991

Human astrocytoma U251 RNA and genomic brain glycogen phosphorylase sequences

Roscoe, J. A., Gorin, F. A. & Tait, R. C., 1991, In : Molecular Brain Research. 10, 3, p. 273-275 3 p.

Research output: Contribution to journalArticle

3 Scopus citations

Reduced glycolytic metabolism in regenerated fast-twitch skeletal muscle

Wineinger, M. A., Gorin, F. A., Tait, R., Froman, B. & Carlsen, R. C., 1991, In : American Journal of Physiology - Cell Physiology. 261, 1 30-1

Research output: Contribution to journalArticle

3 Scopus citations

The gene encoding rat liver glycogen phosphorylase contains multiple polyadenylation signal sequences

Froman, B. E., Tait, R. C., Gorin, F. A., Horwitz, B. A. & Stern, J. S., Dec 30 1991, In : Gene. 109, 2, p. 269-274 6 p.

Research output: Contribution to journalArticle

3 Scopus citations
1990

Brain isozyme of glycogen phosphorylase: immunohistologicall localization within the central nervous system

Ignacio, P. C., Baldwin, B. A., Vijayan, V. K., Tait, R. C. & Gorin, F. A., Oct 8 1990, In : Brain Research. 529, 1-2, p. 42-49 8 p.

Research output: Contribution to journalArticle

63 Scopus citations