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Fredric A Gorin, MD; PhD

Professor

  • 1788 Citations
  • 24 h-Index
1972 …2018
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  • 1 Similar Profiles
Glycogen Phosphorylase Medicine & Life Sciences
Muscles Medicine & Life Sciences
Isoenzymes Medicine & Life Sciences
Glioma Medicine & Life Sciences
Phosphorylases Medicine & Life Sciences
Muscle Chemical Compounds
Amiloride Medicine & Life Sciences
Skeletal Muscle Medicine & Life Sciences

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Projects 1985 2012

Novel Glioma uPA Inhibitor Design Guided by Intracellular signaling Pathways

Gorin, F. A.

National Institutes of Health

9/1/09 → 1/31/12

Project: Research project

Plasminogen Inactivators
Urokinase-Type Plasminogen Activator
Glioma
Plasminogen Activators
Amiloride

Inhibition of Na-H Exchanger Selectively Kills Gliomas

Gorin, F. A.

National Institutes of Health

6/1/01 → 3/31/10

Project: Research project

Glioma
Amiloride
Sodium-Hydrogen Antiporter
Brain Neoplasms
Astrocytes

BRAIN GLYCOGEN PHOSPHORYLASE IN HYPOXIC-ISCHEMIC EVENTS

Gorin, F. A.

National Institutes of Health

9/1/85 → 8/31/87

Project: Research project

Glycogen Phosphorylase
Phosphorylases
Brain
Isoenzymes
Rabbits

Research Output 1972 2018

  • 1788 Citations
  • 24 h-Index
  • 65 Article
  • 1 Chapter
  • 1 Conference contribution
  • 1 Review article
3 Citations (Scopus)

In Vivo MRI of Functionalized Iron Oxide Nanoparticles for Brain Inflammation

Tang, T., Valenzuela, A., Petit, F., Chow, S., Leung, K., Gorin, F. A., Louie, A. Y. & Dhenain, M., Jan 1 2018, In : Contrast Media and Molecular Imaging. 2018, 3476476.

Research output: Contribution to journal › Article

Microglia
Encephalitis
Nanoparticles
Class A Scavenger Receptors
Dextrans
1 Citation (Scopus)

Label-free fluorescence lifetime spectroscopy detects radiation-induced necrotic changes in live brain in real-time

Hartl, B. A., Ma, H. S. W., Sridharan, S., Hansen, K. S., Kent, M. S., Gorin, F. A., Fragoso, R. C. & Marcu, L., Aug 1 2018, In : Biomedical Optics Express. 9, 8, p. 3559-3580 22 p., 323491.

Research output: Contribution to journal › Article

Fluorescence Spectrometry
brain
Radiation
life (durability)
fluorescence

Killing Glioma 'Stem-like' Cells via Drug-Induced Relocation of Endosomal Urokinase Proteins

Gorin, F. A., Pasupuleti, N., Mahajan, D. & Dugar, S., 2017, In : Anti-Cancer Agents in Medicinal Chemistry. 17, 1, p. 40-47 8 p.

Research output: Contribution to journal › Review article

Urokinase-Type Plasminogen Activator
Glioma
Stem Cells
Pharmaceutical Preparations
Proteins
5 Citations (Scopus)

A novel carboline derivative inhibits nitric oxide formation in macrophages independent of effects on tumor necrosis factor α and interleukin-1β expression

Grodzki, A., Poola, B., Pasupuleti, N., Nantz, M. H., Lein, P. J. & Gorin, F. A., Mar 1 2015, In : Journal of Pharmacology and Experimental Therapeutics. 352, 3, p. 438-447 10 p.

Research output: Contribution to journal › Article

Carbolines
Interleukin-1
Nitric Oxide
Tumor Necrosis Factor-alpha
Macrophages
6 Citations (Scopus)

Mis-trafficking of endosomal urokinase proteins triggers drug-induced glioma nonapoptotic cell death

Pasupuleti, N., Grodzki, A. & Gorin, F. A., 2015, In : Molecular Pharmacology. 87, 4, p. 683-696 14 p.

Research output: Contribution to journal › Article

Urokinase-Type Plasminogen Activator
Glioma
Cell Death
Plasminogen Activators
Endosomes