Frederic Chedin

Jasoliya, M., Sacca, F., Sahdeo, S., Chedin, F., Pane, C., Morra, V. B., Filla, A., Pook, M. & Cortopassi, G. A., Jun 1 2019, In : PloS one. 14, 6, e0217776.

Research output: Contribution to journal › Article

Open Access

Friedreich Ataxia

therapeutics

Gene expression

Gene Expression

gene expression

1 Citation (Scopus)

High-resolution, strand-specific R-loop mapping via S9.6-based DNA–RNA immunoprecipitation and high-throughput sequencing

Sanz, L. A. & Chedin, F., Jan 1 2019, In : Nature Protocols.

Research output: Contribution to journal › Article

Open Access

Immunoprecipitation

Throughput

DNA

RNA

RNA Sequence Analysis

1 Citation (Scopus)

Interplay between DNA sequence and negative superhelicity drives R-loop structures

Stolz, R., Sulthana, S., Hartono, S. R., Malig, M., Benham, C. J. & Chedin, F., Jan 1 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 13, p. 6260-6269 10 p.

Research output: Contribution to journal › Article

Open Access

DNA

RNA

Superhelical DNA

Base Pairing

Nucleic Acids

The extruded non-template strand determines the architecture of R-loops

Carrasco-Salas, Y., Malapert, A., Sulthana, S., Molcrette, B., Chazot-Franguiadakis, L., Bernard, P., Chedin, F., Faivre-Moskalenko, C. & Vanoosthuyse, V., Jul 26 2019, In : Nucleic acids research. 47, 13, p. 6783-6795 13 p.

Research output: Contribution to journal › Article

Open Access

Genomic Instability

DNA Breaks

Schizosaccharomyces

Atomic Force Microscopy

DNA

12 Citations (Scopus)

DNA Topoisomerase I differentially modulates R-loops across the human genome

Manzo, S. G., Hartono, S. R., Sanz, L. A., Marinello, J., De Biasi, S., Cossarizza, A., Capranico, G. & Chedin, F., Jul 30 2018, In : Genome Biology. 19, 1, 100.

Research output: Contribution to journal › Article

DNA topoisomerase

Type I DNA Topoisomerase

Human Genome

genome

DNA