• 3139 Citations
  • 28 h-Index
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Fingerprint Dive into the research topics where Frederic Chedin is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

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DNA Medicine & Life Sciences
DNA Methylation Medicine & Life Sciences
Methyltransferases Medicine & Life Sciences
Epigenomics Medicine & Life Sciences
Methylation Medicine & Life Sciences
RNA Medicine & Life Sciences
Chromatin Medicine & Life Sciences
Histone Code Medicine & Life Sciences

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Projects 2015 2019

Gene Silencing
Double-Stranded DNA Breaks

Research Output 1994 2019

3 Citations (Scopus)

Dimethyl fumarate dosing in humans increases frataxin expression: A potential therapy for Friedreich’s Ataxia

Jasoliya, M., Sacca, F., Sahdeo, S., Chedin, F., Pane, C., Morra, V. B., Filla, A., Pook, M. & Cortopassi, G. A., Jun 1 2019, In : PloS one. 14, 6, e0217776.

Research output: Contribution to journalArticle

Open Access
Friedreich Ataxia
Gene expression
Gene Expression
gene expression
2 Citations (Scopus)
Open Access
RNA Sequence Analysis
3 Citations (Scopus)

Interplay between DNA sequence and negative superhelicity drives R-loop structures

Stolz, R., Sulthana, S., Hartono, S. R., Malig, M., Benham, C. J. & Chedin, F., Jan 1 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 13, p. 6260-6269 10 p.

Research output: Contribution to journalArticle

Open Access
Superhelical DNA
Base Pairing
Nucleic Acids
2 Citations (Scopus)

The extruded non-template strand determines the architecture of R-loops

Carrasco-Salas, Y., Malapert, A., Sulthana, S., Molcrette, B., Chazot-Franguiadakis, L., Bernard, P., Chedin, F., Faivre-Moskalenko, C. & Vanoosthuyse, V., Jul 26 2019, In : Nucleic acids research. 47, 13, p. 6783-6795 13 p.

Research output: Contribution to journalArticle

Open Access
Genomic Instability
DNA Breaks
Atomic Force Microscopy
15 Citations (Scopus)

DNA Topoisomerase I differentially modulates R-loops across the human genome

Manzo, S. G., Hartono, S. R., Sanz, L. A., Marinello, J., De Biasi, S., Cossarizza, A., Capranico, G. & Chedin, F., Jul 30 2018, In : Genome Biology. 19, 1, 100.

Research output: Contribution to journalArticle

DNA topoisomerase
Type I DNA Topoisomerase
Human Genome