Research Output 1988 2017

  • 1279 Citations
  • 15 h-Index
  • 33 Article
  • 2 Review article
2017

Central and peripheral reservoirs of feline immunodeficiency virus in cats: a review

Eckstrand, C. D., Sparger, E. E. & Murphy, B. G. Aug 1 2017 In : The Journal of general virology. 98, 8, p. 1985-1996 12 p.

Research output: Research - peer-reviewReview article

Feline Immunodeficiency Virus
Cats
Proviruses
HIV
Viruses
1 Citations

Changes in circulating B cell subsets associated with aging and acute SIV infection in rhesus macaques

William Chang, W. L., Gonzalez, D. F., Kieu, H. T., Castillo, L. D., Messaoudi, I., Shen, X., Tomaras, G. D., Shacklett, B. L., Barry, P. A. & Sparger, E. E. Jan 1 2017 In : PLoS ONE. 12, 1, 0170154

Research output: Research - peer-reviewArticle

B-Lymphocyte Subsets
Simian Immunodeficiency Virus
Virus Diseases
Macaca mulatta
B-Lymphocytes
1 Citations

Peripheral and central immune cell reservoirs in tissues from asymptomatic cats chronically infected with feline immunodeficiency virus

Eckstrand, C. D., Sparger, E. E., Pitt, K. A. & Murphy, B. G. Apr 1 2017 In : PLoS ONE. 12, 4, e0175327

Research output: Research - peer-reviewArticle

Feline immunodeficiency virus
cats
cells
tissues
Feline Immunodeficiency Virus
2016
7 Citations

Blocking indolamine-2,3-dioxygenase rebound immune suppression boosts antitumor effects of radio-immunotherapy in murine models and spontaneous canine malignancies

Monjazeb, A. M., Kent, M. S., Grossenbacher, S. K., Mall, C., Zamora, A. E., Mirsoian, A., Chen, M., Kol, A., Shiao, S. L., Reddy, A., Perks, J. R., Culp, W. T. N., Sparger, E. E., Canter, R. J., Sckisel, G. D. & Murphy, W. J. Sep 1 2016 In : Clinical Cancer Research. 22, 17, p. 4328-4340 13 p.

Research output: Research - peer-reviewArticle

Indoleamine-Pyrrole 2,3,-Dioxygenase
Radio
Immunotherapy
Canidae
Neoplasms
3 Citations

Canine cancer immunotherapy studies: Linking mouse and human

Park, J. S., Withers, S. S., Modiano, J. F., Kent, M. S., Chen, M., Luna, J. I., Culp, W. T. N., Sparger, E. E., Rebhun, R. B., Monjazeb, A. M., Murphy, W. J. & Canter, R. J. Dec 20 2016 In : Journal for ImmunoTherapy of Cancer. 4, 1, 97

Research output: Research - peer-reviewReview article

Immunotherapy
Canidae
Neoplasms
Specific Pathogen-Free Organisms
Tumor Microenvironment

Utilizing a TLR5-adjuvanted cytomegalovirus as a lentiviral vaccine in the nonhuman primate model for AIDS

Deere, J. D., Chang, W. L. W., Castillo, L. D., Schmidt, K. A., Kieu, H. T., Renzette, N., Kowalik, T., Barthold, S. W., Shacklett, B. L., Barry, P. A. & Sparger, E. E. May 1 2016 In : PLoS One. 11, 5, e0155629

Research output: Research - peer-reviewArticle

Simian immunodeficiency virus
Cytomegalovirus
animal models
vaccines
Simian Immunodeficiency Virus
2 Citations

Viral reservoirs in lymph nodes of FIV-infected progressor and long-term non-progressor cats during the asymptomatic phase

Eckstrand, C. D., Hillman, C., Smith, A. L., Sparger, E. E. & Murphy, B. G. Jan 7 2016 In : PLoS One. 11, 1, e0146285

Research output: Research - peer-reviewArticle

Feline immunodeficiency virus
lymph nodes
cats
blood
Feline Immunodeficiency Virus
2013
7 Citations

Feline immunodeficiency virus latency

McDonnel, S. J., Sparger, E. E. & Murphy, B. G. Jul 6 2013 In : Retrovirology. 10, 1, 69

Research output: Research - peer-reviewArticle

Virus Latency
Feline Immunodeficiency Virus
Animal Models
Therapeutics
Proviruses
2012
15 Citations

FIV establishes a latent infection in feline peripheral blood CD4+ T lymphocytes in vivo during the asymptomatic phase of infection

Murphy, B., Vapniarsky, N., Hillman, C., Castillo, D., McDonnel, S., Moore, P., Luciw, P. A. & Sparger, E. E. Feb 7 2012 In : Retrovirology. 9, 12

Research output: Research - peer-reviewArticle

Feline Immunodeficiency Virus
Asymptomatic Infections
Felidae
T-Lymphocytes
Infection
7 Citations

Pharmacologic reactivation of latent feline immunodeficiency virus ex vivo in peripheral CD4+ T-lymphocytes

McDonnel, S. J., Sparger, E. E., Luciw, P. A. & Murphy, B. G. Dec 2012 In : Virus Research. 170, 1-2, p. 174-179 6 p.

Research output: Research - peer-reviewArticle

Feline Immunodeficiency Virus
T-Lymphocytes
vorinostat
Histone Deacetylase Inhibitors
Histones
9 Citations

Transcriptional regulation of latent feline immunodeficiency virus in peripheral CD4+ T-lymphocytes

McDonnel, S. J., Sparger, E. E., Luciw, P. A. & Murphy, B. G. May 2012 In : Viruses. 4, 5, p. 878-888 11 p.

Research output: Research - peer-reviewArticle

Feline Immunodeficiency Virus
T-Lymphocytes
Cats
Histones
Feline Acquired Immunodeficiency Syndrome
2009
15 Citations

Co-immunization with IL-15 enhances cellular immune responses induced by a vif-deleted simian immunodeficiency virus proviral DNA vaccine and confers partial protection against vaginal challenge with SIVmac251

Dubie, R. A., Maksaereekul, S., Shacklett, B. L., Lemongello, D., Cole, K. S., Villinger, F., Blozis, S. A., Luciw, P. A. & Sparger, E. E. Mar 30 2009 In : Virology. 386, 1, p. 109-121 13 p.

Research output: Research - peer-reviewArticle

Interleukin-15
Simian Immunodeficiency Virus
DNA Vaccines
Cellular Immunity
Immunization

Exploiting the natural history of cytomegalovirus to vaccinate against HIV

Sparger, E. E., Gardner, M. B. & Barry, P. A. Aug 2009 In : Expert Review of Vaccines. 8, 8, p. 993-997 5 p.

Research output: Research - peer-reviewArticle

Natural History
Cytomegalovirus
HIV
AIDS Vaccines
Macaca mulatta
4 Citations

Vaccination with vif-deleted feline immunodeficiency virus provirus, GM-CSF, and TNF-α plasmids preserves global CD4 T lymphocyte function after challenge with FIV

Maksaereekul, S., Dubie, R. A., Shen, X., Kieu, H., Dean, G. A. & Sparger, E. E. Jun 8 2009 In : Vaccine. 27, 28, p. 3754-3765 12 p.

Research output: Research - peer-reviewArticle

proviruses
granulocyte-macrophage colony-stimulating factor
Feline immunodeficiency virus
tumor necrosis factor-alpha
preserves
2008
6 Citations

Vaccination of rhesus macaques with a vif-deleted simian immunodeficiency virus proviral DNA vaccine

Sparger, E. E., Dubie, R. A., Shacklett, B. L., Cole, K. S., Chang, W. L. & Luciw, P. A. May 10 2008 In : Virology. 374, 2, p. 261-272 12 p.

Research output: Research - peer-reviewArticle

Simian Immunodeficiency Virus
DNA Vaccines
Macaca mulatta
Vaccination
Viruses
2007
13 Citations

A feline immunodeficiency virus vif-deletion mutant remains attenuated upon infection of newborn kittens

Shen, X., Leutenegger, C. M., Cole, K. S., Pedersen, N. C. & Sparger, E. E. Oct 2007 In : Journal of General Virology. 88, 10, p. 2793-2799 7 p.

Research output: Research - peer-reviewArticle

Feline Immunodeficiency Virus
Infection
Plasmids
Viruses
T-Lymphocytes
14 Citations

Vaccination of cats with attenuated feline immunodeficiency virus proviral DNA vaccine expressing gamma interferon

Gupta, S., Leutenegger, C. M., Dean, G. A., Steckbeck, J. D., Cole, K. S. & Sparger, E. E. Jan 2007 In : Journal of Virology. 81, 2, p. 465-473 9 p.

Research output: Research - peer-reviewArticle

Feline Immunodeficiency Virus
DNA Vaccines
Interferon-gamma
Vaccination
Cats
2006
3 Citations
Feline Immunodeficiency Virus
Green Fluorescent Proteins
Interferon-gamma
Proviruses
enhanced green fluorescent protein
2004
33 Citations

Feline immunodeficiency virus Orf-A localizes to the nucleus and induces cell cycle arrest

Gemeniano, M. C., Sawai, E. T. & Sparger, E. E. Aug 1 2004 In : Virology. 325, 2, p. 167-174 8 p.

Research output: Research - peer-reviewArticle

Contagious Ecthyma
Feline Immunodeficiency Virus
Cell Cycle Checkpoints
Proteins
Amino Acids
2003
28 Citations

Feline immunodeficiency virus Orf-A is required for virus particle formation and virus infectivity

Gemeniano, M. C., Sawai, E. T., Leutenegger, C. M. & Sparger, E. E. Aug 2003 In : Journal of Virology. 77, 16, p. 8819-8830 12 p.

Research output: Research - peer-reviewArticle

Feline immunodeficiency virus
virion
pathogenicity
viruses
Contagious Ecthyma
2001
13 Citations

Construction and in vitro characterization of attenuated feline immunodeficiency virus long terminal repeat mutant viruses

Bigornia, L., Lockridge, K. M. & Sparger, E. E. 2001 In : Journal of Virology. 75, 2, p. 1054-1060 7 p.

Research output: Research - peer-reviewArticle

Feline Immunodeficiency Virus
Terminal Repeat Sequences
Viruses
In Vitro Techniques
Feline immunodeficiency virus
2000
33 Citations

Protective immunity against feline immunodeficiency virus induced by inoculation with vif-deleted proviral DNA

Lockridge, K. M., Chien, M., Dean, G. A., Stefano Cole, K., Montelaro, R. C., Luciw, P. A. & Sparger, E. E. Jul 20 2000 In : Virology. 273, 1, p. 67-79 13 p.

Research output: Research - peer-reviewArticle

Feline Immunodeficiency Virus
Immunity
DNA
Cats
Cytotoxic T-Lymphocytes
1999
39 Citations

Differential cell tropism of feline immunodeficiency virus molecular clones in vivo

Dean, G. A., Himathongkham, S. & Sparger, E. E. Apr 1999 In : Journal of Virology. 73, 4, p. 2596-2603 8 p.

Research output: Research - peer-reviewArticle

tropisms
Feline immunodeficiency virus
clones
cells
Feline Immunodeficiency Virus
26 Citations

The feline immunodeficiency virus vif gene is required for productive infection of feline peripheral blood mononuclear cells and monocyte-derived macrophages

Lockridge, K. M., Himathongkham, S., Sawai, E. T., Chienand, M. & Sparger, E. E. Aug 15 1999 In : Virology. 261, 1, p. 25-30 6 p.

Research output: Research - peer-reviewArticle

vif Genes
Feline Immunodeficiency Virus
Felidae
Blood Cells
Macrophages
1998
58 Citations

Lessons from the cat: Feline immunodeficiency virus as a tool to develop intervention strategies against human immunodeficiency virus type 1

Elder, J. H., Dean, G. A., Hoover, E. A., Hoxie, J. A., Malim, M. H., Mathes, L., Neil, J. C., North, T. W., Sparger, E., Tompkins, M. B., Tompkins, W. A. F., Yamamoto, J., Yuhki, N., Pedersen, N. C. & Miller, R. H. Jun 10 1998 In : AIDS Research and Human Retroviruses. 14, 9, p. 797-801 5 p.

Research output: Research - peer-reviewArticle

1997
19 Citations

Infection of cats by injection with DNA of a feline immunodeficiency virus molecular clone

Sparger, E. E., Louie, H., Ziomeck, A. M. & Luciw, P. A. Nov 10 1997 In : Virology. 238, 1, p. 157-160 4 p.

Research output: Research - peer-reviewArticle

Feline Immunodeficiency Virus
Cats
Clone Cells
Injections
DNA
1994
12 Citations

Evaluation of in vivo and in vitro interactions of feline immunodeficiency virus and feline leukemia virus

Beebe, A. M., Faith, T. G., Sparger, E. E., Torten, M., Pedersen, N. C. & Dandekar, S. Jul 1994 In : AIDS. 8, 7, p. 873-878 6 p.

Research output: Research - peer-reviewArticle

Feline Leukemia Virus
Feline Immunodeficiency Virus
In Vitro Techniques
Cats
Virus Diseases
38 Citations

Infection of Cats with Molecularly Cloned and Biological Isolates of the Feline Immunodeficiency Virus

Sparger, E. E., Beebe, A. M., Dua, N., Himathongkam, S., Elder, J. H., Torten, M. & Higgins, J. Dec 1994 In : Virology. 205, 2, p. 546-553 8 p.

Research output: Research - peer-reviewArticle

Feline Immunodeficiency Virus
Cats
Infection
Viruses
Felidae
1993
27 Citations
1992
12 Citations

Long-term haematological changes in cats experimentally infected with feline immunodeficiency virus (FIV)

Mandell, C. P., Sparger, E. E., Pedersen, N. C. & Jain, N. C. Feb 1992 In : Comparative Haematology International. 2, 1, p. 8-17 10 p.

Research output: Research - peer-reviewArticle

Feline Immunodeficiency Virus
Cats
Neutropenia
Virus Diseases
Infection
76 Citations

Regulation of gene expression directed by the long terminal repeat of the feline immunodeficiency virus

Sparger, E. E., Shacklett, B. L., Renshaw-Gegg, L., Barry, P. A., Pedersen, N. C., Elder, J. H. & Luciw, P. A. 1992 In : Virology. 187, 1, p. 165-177 13 p.

Research output: Research - peer-reviewArticle

Feline Immunodeficiency Virus
Terminal Repeat Sequences
Gene Expression Regulation
Adenosine Monophosphate
Clone Cells
1990
68 Citations

Feline leukemia virus infection as a potentiating cofactor for the primary and secondary stages of experimentally induced feline immunodeficiency virus infection

Pedersen, N. C., Torten, M., Rideout, B., Sparger, E., Tonachini, T., Luciw, P. A., Ackley, C., Levy, N. & Yamamoto, J. Feb 1990 In : Journal of Virology. 64, 2, p. 598-606 9 p.

Research output: Research - peer-reviewArticle

Feline leukemia virus
Feline immunodeficiency virus
infection
Feline Leukemia Virus
Feline Immunodeficiency Virus
1989
51 Citations

Feline immunodeficiency virus is a lentivirus associated with an AIDS-like disease in cats

Sparger, E. E., Luciw, P. A., Elder, J. H., Yamamoto, J. K., Lowenstine, L. J. & Pedersen, N. C. 1989 In : AIDS. 3, SUPPL. 1

Research output: Research - peer-reviewArticle

315 Citations

Nucleotide sequence and genomic organization of feline immunodeficiency virus

Talbott, R. L., Sparger, E. E., Lovelace, K. M., Fitch, W. M., Pedersen, N. C., Luciw, P. A. & Elder, J. H. 1989 In : Proceedings of the National Academy of Sciences of the United States of America. 86, 15, p. 5743-5747 5 p.

Research output: Research - peer-reviewArticle

Feline Immunodeficiency Virus
Open Reading Frames
Lentivirus
Proviruses
Intergenic DNA
1988
324 Citations

Pathogenesis of experimentally induced feline immunodeficiency virus infection in cats.

Yamamoto, J. K., Sparger, E., Ho, E. W., Andersen, P. R., O'Connor, T. P., Mandell, C. P., Lowenstine, L., Munn, R. & Pedersen, N. C. Aug 1988 In : American Journal of Veterinary Research. 49, 8, p. 1246-1258 13 p.

Research output: Research - peer-reviewArticle

Feline Immunodeficiency Virus
Virus Diseases
Cats
Feline immunodeficiency virus
pathogenesis