• 7189 Citations
  • 50 h-Index
1994 …2020

Research output per year

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Research Output

  • 7189 Citations
  • 50 h-Index
  • 110 Article
  • 4 Review article
  • 3 Chapter
  • 1 Comment/debate
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Article
2020

FMR1 locus isoforms: potential biomarker candidates in fragile X-associated tremor/ataxia syndrome (FXTAS)

Zafarullah, M., Tang, H. T., Durbin-Johnson, B., Fourie, E., Hessl, D. R., Rivera, S. M. & Tassone, F., Dec 1 2020, In : Scientific reports. 10, 1, 11099.

Research output: Contribution to journalArticle

Open Access
2019

Association between IQ and FMR1 protein (FMRP) across the spectrum of CGG repeat expansions

Kim, K., Hessl, D., Randol, J. L., Espinal, G. M., Schneider, A., Protic, D., Aydin, E. Y., Hagerman, R. J. & Hagerman, P. J., Dec 2019, In : PloS one. 14, 12, e0226811.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Cognitive training for children and adolescents with fragile X syndrome: A randomized controlled trial of Cogmed

Hessl, D., Schweitzer, J. B., Nguyen, D. V., McLennan, Y. A., Johnston, C., Shickman, R. & Chen, Y., Apr 15 2019, In : Journal of Neurodevelopmental Disorders. 11, 1, 4.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Effects of mavoglurant on visual attention and pupil reactivity while viewing photographs of faces in Fragile X Syndrome

Hessl, D. R., Harvey, D. J., Sansone, S., Crestodina, C., Chin, J., Joshi, R., Hagerman, R. J. & Berry-Kravis, E., Jan 1 2019, In : PLoS One. 14, 1, e0209984.

Research output: Contribution to journalArticle

4 Scopus citations

Voice of people with fragile X syndrome and their families: Reports from a survey on treatment priorities

Weber, J. D., Smith, E., Berry-Kravis, E., Cadavid, D., Hessl, D. R. & Erickson, C., Jan 1 2019, In : Brain Sciences. 9, 2, 18.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations
2018

Age- and CGG repeat-related slowing of manual movement in fragile X carriers: A prodrome of fragile X-associated tremor ataxia syndrome?

Shickman, R., Famula, J., Tassone, F., Leehey, M., Ferrer, E., Rivera, S. M. & Hessl, D. R., Apr 1 2018, In : Movement Disorders. 33, 4, p. 628-636 9 p.

Research output: Contribution to journalArticle

5 Scopus citations

Assessment of molecular measures in non-FXTAS male premutation carriers

Al Olaby, R. R., Tang, H. T., Durbin-Johnson, B., Schneider, A., Hessl, D. R., Rivera, S. M. & Tassone, F., Aug 22 2018, In : Frontiers in Genetics. 9, AUG, 302.

Research output: Contribution to journalArticle

1 Scopus citations

Best practices in fragile X syndrome treatment development

Erickson, C. A., Kaufmann, W. E., Budimirovic, D. B., Lachiewicz, A., Haas-Givler, B., Miller, R. M., Dixon Weber, J., Abbeduto, L., Hessl, D., Hagerman, R. J. & Berry-Kravis, E., Dec 2018, In : Brain Sciences. 8, 12, 224.

Research output: Contribution to journalArticle

Open Access
10 Scopus citations

Computerized cognitive training in children with autism and intellectual disabilities: Feasibility and satisfaction study

Benyakorn, S., Calub, C. A., Riley, S. J., Schneider, A., Iosif, A-M., Friedman, M. S., Hessl, D. R. & Schweitzer, J. B., May 1 2018, In : Journal of Medical Internet Research. 20, 5, e40.

Research output: Contribution to journalArticle

1 Scopus citations

Effect of the mGluR5-NAM Basimglurant on Behavior in Adolescents and Adults with Fragile X Syndrome in a Randomized, Double-Blind, Placebo-Controlled Trial: FragXis Phase 2 Results

Youssef, E. A., Berry-Kravis, E., Czech, C., Hagerman, R. J., Hessl, D. R., Wong, C. Y., Rabbia, M., Deptula, D., John, A., Kinch, R., Drewitt, P., Lindemann, L., Marcinowski, M., Langland, R., Horn, C., Fontoura, P., Santarelli, L. & Quiroz, J. A., Feb 1 2018, In : Neuropsychopharmacology. 43, 3, p. 503-512 10 p.

Research output: Contribution to journalArticle

37 Scopus citations

Extending the Parent-Delivered Early Start Denver Model to Young Children with Fragile X Syndrome

Vismara, L. A., McCormick, C. E. B., Shields, R. & Hessl, D. R., Jan 1 2018, (Accepted/In press) In : Journal of Autism and Developmental Disorders.

Research output: Contribution to journalArticle

4 Scopus citations

Middle cerebellar peduncle width-A novel MRI biomarker for FXTAS?

Shelton, A. L., Wang, J. Y., Fourie, E., Tassone, F., Chen, A., Frizzi, L., Hagerman, R. J., Ferrer, E., Hessl, D. R. & Rivera, S. M., Jun 25 2018, In : Frontiers in Neuroscience. 12, JUN, 379.

Research output: Contribution to journalArticle

4 Scopus citations

Presence of middle cerebellar peduncle sign in FMR1 premutation carriers without tremor and ataxia

Famula, J. L., McKenzie, F., McLennan, Y. A., Grigsby, J., Tassone, F., Hessl, D. R., Rivera, S. M., Martinez-Cerdeno, V. & Hagerman, R. J., Aug 22 2018, In : Frontiers in Neurology. 9, AUG, 695.

Research output: Contribution to journalArticle

5 Scopus citations
2017

Abnormal trajectories in cerebellum and brainstem volumes in carriers of the fragile X premutation

Wang, J. Y., Hessl, D. R., Hagerman, R. J., Simon, T. J., Tassone, F., Ferrer, E. & Rivera, S. M., Jul 1 2017, In : Neurobiology of Aging. 55, p. 11-19 9 p.

Research output: Contribution to journalArticle

18 Scopus citations

A randomized double-blind, placebo-controlled trial of ganaxolone in children and adolescents with fragile X syndrome

Ligsay, A., Van Dijck, A., Nguyen, D. V., Lozano, R., Chen, Y., Bickel, E. S., Hessl, D. R., Schneider, A., Angkustsiri, K., Tassone, F., Ceulemans, B., Kooy, R. F. & Hagerman, R. J., Aug 2 2017, In : Journal of Neurodevelopmental Disorders. 9, 1, 26.

Research output: Contribution to journalArticle

19 Scopus citations

Autism Spectrum Disorder in Males with Sex Chromosome Aneuploidy: XXY/Klinefelter Syndrome, XYY, and XXYY

Tartaglia, N. R., Wilson, R., Miller, J. S., Rafalko, J., Cordeiro, L., Davis, S., Hessl, D. R. & Ross, J., Apr 1 2017, In : Journal of Developmental and Behavioral Pediatrics. 38, 3, p. 197-207 11 p.

Research output: Contribution to journalArticle

27 Scopus citations

Clinical and molecular correlates in fragile X premutation females

Jiraanont, P., Sweha, S. R., AlOlaby, R. R., Silva, M., Tang, H. T., Durbin-Johnson, B., Schneider, A., Espinal, G. M., Hagerman, P. J., Rivera, S. M., Hessl, D. R., Hagerman, R. J., Chutabhakdikul, N. & Tassone, F., Jun 1 2017, In : eNeurologicalSci. 7, p. 49-56 8 p.

Research output: Contribution to journalArticle

3 Scopus citations
2016

Aging in Fragile X Premutation Carriers

Lozano, R., Saito, N., Reed, D., Eldeeb, M., Schneider, A., Hessl, D. R., Tassone, F., Beckett, L. A. & Hagerman, R. J., Oct 1 2016, In : Cerebellum. 15, 5, p. 587-594 8 p.

Research output: Contribution to journalArticle

5 Scopus citations

A Randomized, Double-Blind, Placebo-Controlled Trial of Low-Dose Sertraline in Young Children With Fragile X Syndrome

Greiss Hess, L., Fitzpatrick, S. E., Nguyen, D. V., Chen, Y., Gaul, K. N., Schneider, A., Lemons Chitwood, K., Eldeeb, M. A. A. A., Polussa, J., Hessl, D. R., Rivera, S. & Hagerman, R. J., Aug 24 2016, (Accepted/In press) In : Journal of Developmental and Behavioral Pediatrics.

Research output: Contribution to journalArticle

29 Scopus citations

Broad autism spectrum and obsessive–compulsive symptoms in adults with the fragile X premutation

Schneider, A., Johnston, C., Tassone, F., Sansone, S., Hagerman, R. J., Ferrer, E., Rivera, S. M. & Hessl, D. R., Aug 17 2016, In : Clinical Neuropsychologist. 30, 6, p. 929-943 15 p.

Research output: Contribution to journalArticle

10 Scopus citations

Fragile X-associated tremor/ataxia syndrome: another phenotype of the fragile X gene

Hessl, D. R. & Grigsby, J., Aug 17 2016, In : Clinical Neuropsychologist. 30, 6, p. 810-814 5 p.

Research output: Contribution to journalArticle

2 Scopus citations

Psychiatric disorders among women with the fragile X premutation without children affected by fragile X syndrome

Gossett, A., Sansone, S., Schneider, A., Johnston, C., Hagerman, R. J., Tassone, F., Rivera, S. M., Seritan, A. L. & Hessl, D. R., Dec 1 2016, In : American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 171, 8, p. 1139-1147 9 p.

Research output: Contribution to journalArticle

6 Scopus citations

Robust machine learning-based correction on automatic segmentation of the cerebellum and brainstem

Wang, J. Y., Ngo, M. M., Hessl, D. R., Hagerman, R. J. & Rivera, S. M., May 1 2016, In : PLoS One. 11, 5, e0156123.

Research output: Contribution to journalArticle

10 Scopus citations

The NIH Toolbox Cognitive Battery for intellectual disabilities: Three preliminary studies and future directions

Hessl, D. R., Sansone, S. M., Berry-Kravis, E., Riley, K., Widaman, K. F., Abbeduto, L. J., Schneider, A., Coleman, J., Oaklander, D., Rhodes, K. C. & Gershon, R. C., Sep 6 2016, In : Journal of Neurodevelopmental Disorders. 8, 1, 35.

Research output: Contribution to journalArticle

30 Scopus citations
2015
17 Scopus citations

Psychological status in female carriers of premutation FMR1 allele showing a complex relationship with the size of CGG expansion

Loesch, D. Z., Bui, M. Q., Hammersley, E., Schneider, A., Storey, E., Stimpson, P., Burgess, T., Francis, D., Slater, H., Tassone, F., Hagerman, R. J. & Hessl, D. R., Feb 1 2015, In : Clinical Genetics. 87, 2, p. 173-178 6 p.

Research output: Contribution to journalArticle

25 Scopus citations

Psychophysiological Responses to Emotional Stimuli in Children and Adolescents with Autism and Fragile X Syndrome

Cohen, S., Masyn, K., Mastergeorge, A. & Hessl, D. R., Mar 4 2015, In : Journal of Clinical Child and Adolescent Psychology. 44, 2, p. 250-263 14 p.

Research output: Contribution to journalArticle

23 Scopus citations
2014

A family with two female siblings with compound heterozygous FMR1 premutation alleles

Basuta, K., Lozano, R., Schneider, A., Yrigollen, C. M., Hessl, D. R., Hagerman, R. J. & Tassone, F., 2014, In : Clinical Genetics. 85, 5, p. 458-463 6 p.

Research output: Contribution to journalArticle

3 Scopus citations

Anxiety, attention problems, hyperactivity, and the Aberrant Behavior Checklist in fragile X syndrome

Wheeler, A., Raspa, M., Bann, C., Bishop, E., Hessl, D. R., Sacco, P. & Bailey, D. B., Jan 2014, In : American Journal of Medical Genetics, Part A. 164, 1, p. 141-155 15 p.

Research output: Contribution to journalArticle

28 Scopus citations

Association between macroorchidism and intelligence in FMR1 premutation carriers

Lozano, R., Summers, S., Lozano, C., Mu, Y., Hessl, D. R., Nguyen, D., Tassone, F. & Hagerman, R. J., 2014, In : American Journal of Medical Genetics, Part A. 164, 9, p. 2206-2211 6 p.

Research output: Contribution to journalArticle

4 Scopus citations

Electrodermal and behavioral responses of children with autism spectrum disorders to sensory and repetitive stimuli

Mccormick, C., Hessl, D. R., Macari, S. L., Ozonoff, S. J., Green, C. & Rogers, S. J., 2014, In : Autism Research. 7, 4, p. 468-480 13 p.

Research output: Contribution to journalArticle

22 Scopus citations

Emotion potentiated startle in fragile X syndrome

Ballinger, E. C., Cordeiro, L., Chavez, A. D., Hagerman, R. J. & Hessl, D. R., 2014, In : Journal of Autism and Developmental Disorders. 44, 10, p. 2536-2546 11 p.

Research output: Contribution to journalArticle

3 Scopus citations

Fear-specific amygdala function in children and adolescents on the fragile x spectrum: A dosage response of the FMR1 gene

Kim, S. Y., Burris, J., Bassal, F., Koldewyn, K., Chattarji, S., Tassone, F., Hessl, D. R. & Rivera, S. M., Mar 2014, In : Cerebral Cortex. 24, 3, p. 600-613 14 p.

Research output: Contribution to journalArticle

22 Scopus citations

Feasibility, reproducibility, and clinical validity of the pediatric anxiety rating scale - Revised for fragile X syndrome

Russo-Ponsaran, N. M., Yesensky, J., Hessl, D. R. & Berry-Kravis, E., Jan 2014, In : American Journal on Intellectual and Developmental Disabilities. 119, 1, p. 1-16 16 p.

Research output: Contribution to journalArticle

9 Scopus citations

Improving IQ measurement in intellectual disabilities using true deviation from population norms

Sansone, S. M., Schneider, A., Bickel, E., Berry-Kravis, E., Prescott, C. & Hessl, D. R., Jul 8 2014, In : Journal of Neurodevelopmental Disorders. 6, 1, 16.

Research output: Contribution to journalArticle

30 Scopus citations

The autism spectrum disorders stem cell resource at children’s hospital of orange county: Implications for disease modeling and drug discovery

Brick, D. J., Nethercott, H. E., Montesano, S., Banuelos, M. G., Stover, A. E., Schutte, S. S., O’dowd, D. K., Hagerman, R. J., Ono, M., Hessl, D. R., Tassone, F. & Schwartz, P. H., 2014, In : Stem cells translational medicine. 3, 11, p. 1275-1287 13 p.

Research output: Contribution to journalArticle

18 Scopus citations
2013

A randomized double-blind, placebo-controlled trial of minocycline in children and adolescents with fragile x syndrome

Leigh, M. J. S., Nguyen, D. V., Mu, Y., Winarni, T. I., Schneider, A., Chechi, T., Polussa, J., Doucet, P., Tassone, F., Rivera, S. M., Hessl, D. R. & Hagerman, R. J., Apr 2013, In : Journal of Developmental and Behavioral Pediatrics. 34, 3, p. 147-155 9 p.

Research output: Contribution to journalArticle

140 Scopus citations

Electrocortical changes associated with minocycline treatment in fragile X syndrome

Schneider, A., Leigh, M. J., Adams, P., Nanakul, R., Chechi, T., Olichney, J. M., Hagerman, R. J. & Hessl, D. R., Oct 2013, In : Journal of Psychopharmacology. 27, 10, p. 956-963 8 p.

Research output: Contribution to journalArticle

55 Scopus citations

Fragile X-associated tremor/ataxia syndrome influence of the FMR1 gene on motor fiber tracts in males with normal and premutation alleles

Wang, J. Y., Hessl, D. R., Schneider, A., Tassone, F., Hagerman, R. J. & Rivera, S. M., Aug 2013, In : JAMA Neurology. 70, 8, p. 1022-1029 8 p.

Research output: Contribution to journalArticle

40 Scopus citations
17 Scopus citations

Influence of the fragile X mental retardation (FMR1) gene on the brain and working memory in men with normal FMR1 alleles

Wang, J. Y., Hessl, D. R., Iwahashi, C., Cheung, K., Schneider, A., Hagerman, R. J., Hagerman, P. J. & Rivera, S. M., Jan 15 2013, In : NeuroImage. 65, p. 288-298 11 p.

Research output: Contribution to journalArticle

19 Scopus citations

Outcome measures for clinical trials in fragile X syndrome

Berry-Kravis, E., Hessl, D. R., Abbeduto, L. J., Reiss, A. L., Beckel-Mitchener, A. & Urv, T. K., Sep 2013, In : Journal of Developmental and Behavioral Pediatrics. 34, 7, p. 508-522 15 p.

Research output: Contribution to journalArticle

81 Scopus citations
6 Scopus citations
2012

Age-dependent structural connectivity effects in fragile X premutation

Wang, J. Y., Hessl, D. R., Hagerman, R. J., Tassone, F. & Rivera, S. M., Apr 2012, In : Archives of Neurology. 69, 4, p. 482-489 8 p.

Research output: Contribution to journalArticle

40 Scopus citations

Effects of STX209 (Arbaclofen) on neurobehavioral function in children and adults with fragile X syndrome: A randomized, controlled, phase 2 trial

Berry-Kravis, E. M., Hessl, D. R., Rathmell, B., Zarevics, P., Cherubini, M., Walton-Bowen, K., Mu, Y., Nguyen, D. V., Gonzalez-Heydrich, J., Wang, P. P., Carpenter, R. L., Bear, M. F. & Hagerman, R. J., Sep 19 2012, In : Science Translational Medicine. 4, 152, 152ra127.

Research output: Contribution to journalArticle

215 Scopus citations

Feasibility, reliability, and clinical validity of the test of attentional performance for Children (KiTAP) in fragile X syndrome (FXS)

Knox, A., Schneider, A., Abucayan, F., Hervey, C., Tran, C., Hessl, D. R. & Berry-Kravis, E., 2012, In : Journal of Neurodevelopmental Disorders. 4, 1, p. 1-12 12 p.

Research output: Contribution to journalArticle

20 Scopus citations

Hypertension in FMR1 premutation males with and without fragile X-associated tremor/ataxia syndrome (FXTAS)

Hamlin, A. A., Sukharev, D., Campos, L., Mu, Y., Tassone, F., Hessl, D. R., Nguyen, D. V., Loesch, D. & Hagerman, R. J., Jun 2012, In : American Journal of Medical Genetics, Part A. 158 A, 6, p. 1304-1309 6 p.

Research output: Contribution to journalArticle

37 Scopus citations

Increased prevalence of seizures in boys who were probands with the FMR1 premutation and co-morbid autism spectrum disorder

Chonchaiya, W., Au, J., Schneider, A., Hessl, D. R., Harris, S. W., Laird, M., Mu, Y., Tassone, F., Nguyen, D. V. & Hagerman, R. J., Apr 2012, In : Human Genetics. 131, 4, p. 581-589 9 p.

Research output: Contribution to journalArticle

79 Scopus citations

Prepulse inhibition in patients with fragile X-associated tremor ataxia syndrome

Schneider, A., Ballinger, E., Chavez, A., Tassone, F., Hagerman, R. J. & Hessl, D. R., Jun 2012, In : Neurobiology of Aging. 33, 6, p. 1045-1053 9 p.

Research output: Contribution to journalArticle

14 Scopus citations