David P Richman, MD

Professor

  • 3532 Citations
  • 31 h-Index
1969 …2020

Research output per year

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Research Output

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Article
2019
1 Scopus citations

Validation of the triple timed up-and-go test in Lambert-Eaton myasthenia

on behalf of the DAPPER Study Team, Jan 1 2019, In : Muscle and Nerve. 60, 3, p. 292-298 7 p.

Research output: Contribution to journalArticle

2 Scopus citations
2018

3,4-diaminopyridine base effectively treats the weakness of Lambert-Eaton myasthenia

Sanders, D. B., Juel, V. C., Harati, Y., Smith, A. G., Peltier, A. C., Marburger, T., Lou, J. S., Pascuzzi, R. M., Richman, D. P., Xie, T., Demmel, V., Jacobus, L. R., Aleš, K. L. & Jacobus, D. P., Jan 1 2018, (Accepted/In press) In : Muscle and Nerve.

Research output: Contribution to journalArticle

12 Scopus citations
2017

Population pharmacokinetics/pharmacodynamics of 3,4-diaminopyridine free base in patients with Lambert-Eaton myasthenia

Thakkar, N., Aleš, K., Jacobus, D., Jacobus, L., Peloquin, C., Cohen-Wolkowiez, M., Gonzalez, D., Juel, V. C., Guptill, J. T., Massey, J. M., Hobson-Webb, L. D., Beck, K., Harati, Y., Arvantaj, A., Phan, C., Mousavi, S., Mac-Adam, C., Smith, A. G., Rob Singleton, J., Latner, C. & 24 others, Lessard, M., Peltier, A., Donofrio, P., Lee, C., Artibee, K., Lou, J. S., Marburger, T., Dimitrova, A., Burroughs, B., Jafari, G., Khoury, J., Satayaprasert, M., Dimitrova, D., Pascuzzi, R. M., Bodkin, C., Kincaid, J., Snook, R., Micheels, A., Guingrich, S., Richman, D. P., Agius, M. A., Butters, J., Lindsay, M. & Khalatyan, V., Sep 1 2017, In : CPT: Pharmacometrics and Systems Pharmacology. 6, 9, p. 525-534 10 p.

Research output: Contribution to journalArticle

5 Scopus citations
100 Scopus citations
2016

Acute Stroke Despite Dabigatran Anticoagulation Treated with Idarucizumab and Intravenous Tissue Plasminogen Activator

Bissig, D., Manjunath, R., Traylor, B. R., Richman, D. P. & Ng, K., Oct 28 2016, (Accepted/In press) In : Journal of Stroke and Cerebrovascular Diseases.

Research output: Contribution to journalArticle

7 Scopus citations

Myasthenia gravis exacerbation after discontinuing mycophenolate

Oskarsson, B. E., Rocke, D. M., Dengel, K. & Richman, D. P., Mar 22 2016, In : Neurology. 86, 12, p. 1159-1163 5 p.

Research output: Contribution to journalArticle

13 Scopus citations
2015

A genome-wide association study of myasthenia gravis

Renton, A. E., Pliner, H. A., Provenzano, C., Evoli, A., Ricciardi, R., Nalls, M. A., Marangi, G., Abramzon, Y., Arepalli, S., Chong, S., Hernandez, D. G., Johnson, J. O., Bartoccioni, E., Scuderi, F., Maestri, M., Gibbs, J. R., Errichiello, E., Chiò, A., Restagno, G., Sabatelli, M. & 35 others, Macek, M., Scholz, S. W., Corse, A., Chaudhry, V., Benatar, M., Barohn, R. J., McVey, A., Pasnoor, M., Dimachkie, M. M., Rowin, J., Kissel, J., Freimer, M., Kaminski, H. J., Sanders, D. B., Lipscomb, B., Massey, J. M., Chopra, M., Howard, J. F., Koopman, W. J., Nicolle, M. W., Pascuzzi, R. M., Pestronk, A., Wulf, C., Florence, J., Blackmore, D., Soloway, A., Siddiqi, Z., Muppidi, S., Wolfe, G., Richman, D. P., Mezei, M. M., Jiwa, T., Oger, J., Drachman, D. B. & Traynor, B. J., Apr 1 2015, In : JAMA Neurology. 72, 4, p. 396-404 9 p.

Research output: Contribution to journalArticle

72 Scopus citations

Myasthenia gravis and related disorders: Pathology and molecular pathogenesis

Ha, J. C. & Richman, D. P., Apr 1 2015, In : Biochimica et Biophysica Acta - Molecular Basis of Disease. 1852, 4, p. 651-657 7 p.

Research output: Contribution to journalArticle

29 Scopus citations

The future of research in myasthenia

Richman, D. P., Jul 1 2015, In : JAMA Neurology. 72, 7, p. 812-814 3 p.

Research output: Contribution to journalArticle

2 Scopus citations
2014

Corrigendum to "Structural characterization of the main immunogenic region of the Torpedo acetylcholine receptor" [Mol. Immunol. 58 (2014) 116-131]

Morell, S. W., Trinh, V. B., Gudipati, E., Friend, A., Page, N. A., Agius, M. A., Richman, D. P. & Fairclough, R. H., May 2014, In : Molecular Immunology. 59, 1, p. 117 1 p.

Research output: Contribution to journalArticle

How clinical trials of myasthenia gravis can inform pre-clinical drug development

Rostedt Punga, A., Kaminski, H. J., Richman, D. P. & Benatar, M., Oct 1 2014, In : Experimental Neurology. 270, p. 78-81 4 p.

Research output: Contribution to journalArticle

4 Scopus citations

Limited utility of current MRI criteria for distinguishing multiple sclerosis from common mimickers: Primary and secondary CNS vasculitis, lupus and Sjogren's syndrome

Kim, S. S., Richman, D. P., Johnson, W. O., Hald, J. K. & Agius, M. A., Jan 2014, In : Multiple Sclerosis. 20, 1, p. 57-63 7 p.

Research output: Contribution to journalArticle

24 Scopus citations

Structural characterization of the main immunogenic region of the Torpedo acetylcholine receptor

Morell, S. W., Trinh, V. B., Gudipati, E., Friend, A., Page, N. A., Agius, M. A., Richman, D. P. & Fairclough, R. H., Mar 2014, In : Molecular Immunology. 58, 1, p. 116-131 16 p.

Research output: Contribution to journalArticle

2 Scopus citations
2012

Acute severe animal model of anti-muscle-specific kinase myasthenia: Combined postsynaptic and presynaptic changes

Richman, D. P., Nishi, K., Morell, S. W., Mi Chang, J., Ferns, M. J., Wollmann, R. L., Maselli, R. A., Schnier, J. & Agius, M. A., Apr 2012, In : Archives of Neurology. 69, 4, p. 453-460 8 p.

Research output: Contribution to journalArticle

40 Scopus citations

Animal models of antimuscle-specific kinase myasthenia

Richman, D. P., Nishi, K., Ferns, M. J., Schnier, J., Pytel, P., Maselli, R. A. & Agius, M. A., Dec 2012, In : Annals of the New York Academy of Sciences. 1274, 1, p. 140-147 8 p.

Research output: Contribution to journalArticle

8 Scopus citations

Antibodies to low density lipoprotein receptor-related protein 4 in seronegative myasthenia gravis

Richman, D. P., Apr 2012, In : Archives of Neurology. 69, 4, p. 434-435 2 p.

Research output: Contribution to journalArticle

5 Scopus citations

Current Pharmacologic Management in Selected Neuromuscular Diseases

Skalsky, A. J., Oskarsson, B. E., Han, J. J. & Richman, D. P., Nov 2012, In : Physical Medicine and Rehabilitation Clinics of North America. 23, 4, p. 801-820 20 p.

Research output: Contribution to journalArticle

Dominantly inherited myotonia congenita resulting from a mutation that increases open probability of the muscle chloride channel CLC-1

Richman, D. P., Yu, Y., Lee, T. T., Tseng, P. Y., Yu, W. P., Maselli, R. A., Tang, C. Y. & Chen, T-Y., Dec 2012, In : NeuroMolecular Medicine. 14, 4, p. 328-337 10 p.

Research output: Contribution to journalArticle

8 Scopus citations
2011

Accelerated central nervous system autoimmunity in BAFF-receptor-deficient mice

Kim, S. S., Richman, D. P., Zamvil, S. S. & Agius, M. A., Jul 15 2011, In : Journal of the Neurological Sciences. 306, 1-2, p. 9-15 7 p.

Research output: Contribution to journalArticle

20 Scopus citations

Cerebral venous sinus thrombosis presenting with auditory hallucinations and illusions

Wong, V. S. S., Adamczyk, P., Dahlin, B. C., Richman, D. P. & Wheelock, V. L., Mar 2011, In : Cognitive and Behavioral Neurology. 24, 1, p. 40-42 3 p.

Research output: Contribution to journalArticle

4 Scopus citations

Treatment of myasthenia gravis based on its immunopathogenesis

Kim, J. Y., Park, K. D. & Richman, D. P., 2011, In : Journal of Clinical Neurology (Korea). 7, 4, p. 173-183 11 p.

Research output: Contribution to journalArticle

28 Scopus citations
2008

An international, phase III, randomized trial of mycophenolate mofetil in myasthenia gravis

Sanders, D. B., Hart, I. K., Mantegazza, R., Shukla, S. S., Siddiqi, Z. A., De Baets, M. H. V., Melms, A., Nicolle, M. W., Solomons, N. & Richman, D. P., Aug 5 2008, In : Neurology. 71, 6, p. 400-406 7 p.

Research output: Contribution to journalArticle

185 Scopus citations

Variable phenotypes associated with mutations in DOK7

Anderson, J. A., Ng, J. J., Bowe, C., McDonald, C. M., Richman, D. P., Wollmann, R. L. & Maselli, R. A., Apr 2008, In : Muscle and Nerve. 37, 4, p. 448-456 9 p.

Research output: Contribution to journalArticle

37 Scopus citations
2005

Interrater agreement in the assessment of motor manifestations of Huntington's disease

Hogarth, P., Kayson, E., Kieburtz, K., Marder, K., Oakes, D., Rosas, D., Shoulson, I., Wexler, N. S., Young, A. B., Zhao, H., Adler, C., Albin, R., Ashizawa, T., Bird, T., Blindauer, K., Bundlie, S., Caress, J., Caviness, J., Chouinard, S., Comella, C. & 76 others, Como, P., Corey-Bloom, J., Counihan, T., Deckel, W., Dubinsky, R., Duffy, J., Dure, L., Factor, S., Feigin, A., Fernandez, H., Friedman, J., Greenamyre, T., Guttman, M., Hauser, R., Hersch, S., Hersh, B., Hickenbottom, S., Higgins, D., Hobson, D., Jackson, G., Jankovic, J., Jennings, D., Johnson, W., Koller, W., Louis, E., Lafontaine, A. L., Leventhal, C., Mallonee, W., Marder, K., Marek, K., Martin, W., Mentis, M., Molho, E., Nance, M., O'Brien, C., Orme, C., Palmer, D., Paulsen, J., Paulson, G., Percy, A., Perlman, S., Perlmutter, J., Podskalny, G., Quiad, K., Racette, B., Rachez-Ramos, J., Raymond, L., Richman, D., Roberts, T., Rodnitzky, R., Ross, C., Rouleau, G., Rubin, A., Sax, D., Schimke, N., Shannon, K., Shelton, P., Shinaman, A., Shinobu, L., Shults, C., Siemers, E., Suchowersky, O., Walker, F., Weiner, W., Wheelock, V., Wojcieszek, J., Wooten, F., Bonilla, E., Cha, J. H., de Young, M., Fischbeck, K., Negrette, A., Penney, J. B., Ramos, M., Snodgrass, R. & Thompson, L., Mar 2005, In : Movement Disorders. 20, 3, p. 293-297 5 p.

Research output: Contribution to journalArticle

49 Scopus citations

Relapse rates and enhancing lesions in a phase II trial of natalizumab in multiple sclerosis

O'Connor, P., Miller, D., Riester, K., Yang, M., Panzara, M., Dalton, C., Miszkiel, K., Khan, O., Rice, G., Sheremata, W., Barker, G. J., MacManus, D. G., Webb, C., Middleditch, C., Lewis, S., Pepple, T., Riddle, E., Coombs, C., Agius, M., Richman, D. P. & 79 others, Adams, J., Buonocore, M., Al-Omaishi, J., Markopoulou, K., Healey, K., Sorensen, P., Bates, D., Forsyth, J., Curlis, J., English, P., Blumhardt, L., Orpe, V., Jaspen, T., Bowen, J., Chang, M., Lew, H., Burke, M., Richards, T., Carter, J. L., Dodick, D., Takata, J., Malikowski, M., Nelson, K., Cross, D. A. H., Trotter, J., Derrington, D., Lauber, J., Martinez, C., Foster, G., Conturo, T., Devonshire, V., Oger, J., Wang, L., Morrison, W., Costley, L., Hawkins, C., Mathews, C., Gibson, C., Hebert, J., Rozentsvit, I., Capolino, L., Kelly, J. P., Kaufman, M., Putman, S., Diedrich, A., Follmer, R., Dombrowski, S., Graves, C., Harwick, B., Tselis, A. C., Din, M., Caon, C., Cochran, M., Latif, Z., Lisak, R. P., Zvartau-Hinds, M., Metz, L., Scott, J., Patry, D., Yeung, M., Heuser, J., Wallace, C., Curtis, S., Miller, A., Drexler, E., Keilson, M. J., Bruining, K., Schneider, A., Wolintz, R., Sciarra, L., Oltazewska, H., Murray, R. S., Bowling, A., Kramer, R. E., Bracht, K., O'Brien, C., Seeberger, L., Leitch, J. & Prenger, E., Oct 2005, In : Multiple Sclerosis. 11, 5, p. 568-572 5 p.

Research output: Contribution to journalArticle

37 Scopus citations
2004

Treatment of autoimmune myasthenia gravis [2] (multiple letters)

Bragdon, A. C., Richman, D. P. & Agius, M. A., Sep 29 2004, In : Neurology. 63, 6, p. 1138-1139 2 p.

Research output: Contribution to journalArticle

2003

Agonist-induced transitions of the acetylcholine receptor

Fairclough, R. H., Agius, M. A., Gudipati, E., Silvian, L., Hamaoka, B., Beltzner, C. C., Lin, M. Y., Chuang, A. R. & Richman, D. P., 2003, In : Annals of the New York Academy of Sciences. 998, p. 101-113 13 p.

Research output: Contribution to journalArticle

1 Scopus citations

Three forms of immune myasthenia

Agius, M. A., Richman, D. P., Fairclough, R. H., Aarli, J., Gilhus, N. E. & Romi, F., 2003, In : Annals of the New York Academy of Sciences. 998, p. 453-456 4 p.

Research output: Contribution to journalArticle

16 Scopus citations

Treatment of autoimmune myasthenia gravis

Richman, D. P. & Agius, M. A., Dec 23 2003, In : Neurology. 61, 12, p. 1652-1661 10 p.

Research output: Contribution to journalArticle

153 Scopus citations

Treatment principles in the management of autoimmune myasthenia gravis

Richman, D. P. & Agius, M. A., 2003, In : Annals of the New York Academy of Sciences. 998, p. 457-472 16 p.

Research output: Contribution to journalArticle

16 Scopus citations
2001

Presynaptic congenital myasthenic syndrome due to quantal release deficiency

Maselli, R. A., Kong, D. Z., Bowe, C. M., McDonald, C. M., Ellis, W. G., Agius, M. A., Gomez, C. M., Richman, D. P. & Wollmann, R. L., Jul 24 2001, In : Neurology. 57, 2, p. 279-289 11 p.

Research output: Contribution to journalArticle

40 Scopus citations

Thymectomy in the treatment of ocular myasthenia gravis

Roberts, P. F., Venuta, F., Rendina, E., De Giacomo, T., Coloni, G. F., Follette, D. M., Richman, D. P. & Benfield, J. R., 2001, In : Journal of Thoracic and Cardiovascular Surgery. 122, 3, p. 562-568 7 p.

Research output: Contribution to journalArticle

66 Scopus citations
1998

Antibody effector mechanisms in myasthenia gravis. The complement hypothesis

Richman, D. P., Agius, M. A., Kirvan, C. A., Gomez, C. M., Fairclough, R. H., Dupont, B. L. & Maselli, R. A., 1998, In : Annals of the New York Academy of Sciences. 841, p. 450-465 16 p.

Research output: Contribution to journalArticle

13 Scopus citations

A role for α(187-199) in the conversion of agonist binding energy to the opening of the acetylcholine receptor ion channel

Fairclough, R. H., Gudipati, E., Lin, M. Y., Twaddle, G. M., Richman, D. P., Burkwall, D. A. & Josephs, R., 1998, In : Annals of the New York Academy of Sciences. 841, p. 87-91 5 p.

Research output: Contribution to journalArticle

1 Scopus citations

Differential surface accessibility of α(187-199) in the torpedo acetylcholine receptor α subunits

Fairclough, R. H., Twaddle, G. M., Gudipati, E., Lin, M. Y. & Richman, D. P., Sep 18 1998, In : Journal of Molecular Biology. 282, 2, p. 317-330 14 p.

Research output: Contribution to journalArticle

10 Scopus citations
1 Scopus citations

Introduction

Richman, D. P., 1998, In : Annals of the New York Academy of Sciences. 841

Research output: Contribution to journalArticle

MAb 383C binds to the α-subunit of the acetylcholine receptor associated with the high-affinity tubocurarine site

Lin, M. Y., Twaddle, G. M., Gudipati, E., Richman, D. P. & Fairclough, R. H., 1998, In : Annals of the New York Academy of Sciences. 841, p. 101-103 3 p.

Research output: Contribution to journalArticle

Mapping the mAb 383C epitope to α2(187-199) of the Torpedo acetylcholine receptor on the three-dimensional model

Fairclough, R. H., Twaddle, G. M., Gudipati, E., Stone, R. J. S., Richman, D. P., Burkwall, D. A. & Josephs, R., Sep 18 1998, In : Journal of Molecular Biology. 282, 2, p. 301-315 15 p.

Research output: Contribution to journalArticle

7 Scopus citations

Quality improvement in neurology residency programs [6] (multiple letters)

Weisberg, L., Goldberg, M., Bradley, W. G., Daube, J., Mendell, J. R., Posner, J., Richman, D., Troost, B. T. & Swift, T. R., 1998, In : Neurology. 51, 3, p. 922-923 2 p.

Research output: Contribution to journalArticle

1997

Cluster of wound botulism in california: Clinical, electrophysiologic, and pathologic study

Maselli, R. A., Ellis, W., Mandler, R. N., Sheikh, F., Senton, G., Knox, S., Salari-Namin, H., Agius, M., Wollmann, R. L. & Richman, D. P., 1997, In : Muscle and Nerve. 20, 10, p. 1284-1295 12 p.

Research output: Contribution to journalArticle

36 Scopus citations

Quality improvement in neurology residency programs: Report of the quality improvement committee of the Association of University Professors of Neurology

Bradley, W. G., Daube, J., Mendell, J. R., Posner, J., Richman, D. P., Troost, B. T. & Swift, T. R., 1997, In : Neurology. 49, 5, p. 1205-1207 3 p.

Research output: Contribution to journalArticle

10 Scopus citations
1994

Acquired myasthenia gravis: Immunopathology

Richman, D. P. & Agius, M. A., 1994, In : Neurologic Clinics. 12, 2, p. 273-284 12 p.

Research output: Contribution to journalArticle

18 Scopus citations

Myasthenia gravis: Pathogenesis and treatment

Richman, D. P. & Agius, M. A., 1994, In : Seminars in Neurology. 14, 2, p. 106-110 5 p.

Research output: Contribution to journalArticle

15 Scopus citations

Pathogenesis of hyperacute experimental autoimmune myasthenia gravis: Acetylcholine receptor/cholinergic site/receptor function/autoimmunity

Mihovilovic, M., Donnelly-Roberts, D., Richman, D. P. & Martinez-Carrion, M., Jun 15 1994, In : Journal of Immunology. 152, 12, p. 5997-6002 6 p.

Research output: Contribution to journalArticle

7 Scopus citations

Transcervical thymectomy for myasthenia gravis

DeFilippi, V. J., Richman, D. P. & Ferguson, M. K., 1994, In : The Annals of Thoracic Surgery. 57, 1, p. 194-197 4 p.

Research output: Contribution to journalArticle

98 Scopus citations
1993

An immunogenic self-peptide for T cells in mice with experimental myasthenia

Xu, Q., Agius, M., Gudipati, E., Fairclough, R. H. & Richman, D. P., 1993, In : Annals of the New York Academy of Sciences. 681, p. 1-4 4 p.

Research output: Contribution to journalArticle

Effector mechanisms of myasthenic antibodies

Richman, D. P., Wollmann, R. L., Maselli, R. A., Gomez, C. M., Corey, A. L., Agius, M. A. & Fairclough, R. H., 1993, In : Annals of the New York Academy of Sciences. 681, p. 264-273 10 p.

Research output: Contribution to journalArticle

10 Scopus citations