• 3513 Citations
  • 28 h-Index
19972020
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Fingerprint Dive into the research topics where Colleen E Clancy is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 19 Similar Profiles
Cardiac Arrhythmias Medicine & Life Sciences
Long QT Syndrome Medicine & Life Sciences
Mutation Medicine & Life Sciences
Action Potentials Medicine & Life Sciences
Ion Channels Medicine & Life Sciences
Computer Simulation Medicine & Life Sciences
Pharmaceutical Preparations Medicine & Life Sciences
Sodium Channels Medicine & Life Sciences

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Projects 2007 2020

Computer Simulation
Pharmacology
Safety
Pharmaceutical Preparations
Drug Interactions
Computer Simulation
Pharmacology
Drug Interactions
Ion Channels
Pharmaceutical Preparations

A Systems Biology Approach to Study Cardiac Arrhythmias: iPS Cells and In Silico Modeling

Clancy, C. E., Quertermous, T., Altman, R. B., [No Value], J. C. & Clancy, C. E.

National Institutes of Health

9/15/155/31/19

Project: Research project

Systems Biology
Computer Simulation
Cardiac Arrhythmias
Sudden Cardiac Death
Long QT Syndrome
Pharmacogenetics
Computer Simulation
Cardiac Arrhythmias
Pharmaceutical Preparations
Therapeutics

Research Output 1997 2019

A demonstration of modularity, reuse, reproducibility, portability and scalability for modeling and simulation of cardiac electrophysiology using Kepler Workflows

Yang, P. C., Purawat, S., Ieong, P. U., Jeng, M. T., DeMarco, K. R., Vorobyov, I., McCulloch, A. D., Altintas, I., Amaro, R. E. & Clancy, C. E., Mar 1 2019, In : PLoS computational biology. 15, 3, p. e1006856

Research output: Contribution to journalArticle

Open Access
Cardiac Electrophysiology
electrophysiology
Kepler
Workflow
Portability
1 Citation (Scopus)
Sodium Channels
Anti-Arrhythmia Agents
Drug Interactions
Molecular Dynamics Simulation
Local Anesthetics
6 Citations (Scopus)

Compartmentalized cAMP signaling associated with lipid raft and non-raft membrane domains in adult ventricular myocytes

Agarwal, S. R., Gratwohl, J., Cozad, M., Yang, P. C., Clancy, C. E. & Harvey, R. D., Apr 23 2018, In : Frontiers in Pharmacology. 9, APR, 332.

Research output: Contribution to journalArticle

Muscle Cells
Lipids
Membranes
Cell Membrane
Prostaglandin E Receptors
6 Citations (Scopus)

Determinants of isoform-specific gating kinetics of hERG1 channel: Combined experimental and simulation study

Perissinotti, L. L., De Biase, P. M., Guo, J., Yang, P. C., Lee, M. C., Clancy, C. E., Duff, H. J. & Noskov, S. Y., Apr 12 2018, In : Frontiers in Physiology. 9, APR, 207.

Research output: Contribution to journalArticle

Protein Isoforms
Action Potentials
Cardiac Electrophysiology
Long QT Syndrome
Markov Chains
8 Citations (Scopus)

Digging into lipid membrane permeation for cardiac ion channel blocker d-sotalol with all-atom simulations

DeMarco, K. R., Bekker, S., Clancy, C. E., Noskov, S. Y. & Vorobyov, I., Feb 1 2018, In : Frontiers in Pharmacology. 9, FEB, 26.

Research output: Contribution to journalArticle

Sotalol
Membrane Lipids
Ion Channels
Membranes
Pharmaceutical Preparations