• 3332 Citations
  • 27 h-Index
19972020
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  • 19 Similar Profiles
Cardiac Arrhythmias Medicine & Life Sciences
Long QT Syndrome Medicine & Life Sciences
Mutation Medicine & Life Sciences
Action Potentials Medicine & Life Sciences
Ion Channels Medicine & Life Sciences
Computer Simulation Medicine & Life Sciences
Pharmaceutical Preparations Medicine & Life Sciences
Sodium Channels Medicine & Life Sciences

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Projects 2007 2020

In silico Safety Pharmacology

Clancy, C. E.

National Institutes of Health

7/5/166/30/20

Project: Research projectResearch Project

Computer Simulation
Pharmacology
Safety
Pharmaceutical Preparations
Drug Interactions

A Systems Biology Approach to Study Cardiac Arrhythmias: iPS Cells and In Silico Modeling

Clancy, C. E., Quertermous, T., Altman, R. B. & [No Value], J. C.

National Institutes of Health

9/15/155/31/19

Project: Research projectResearch Project

Systems Biology
Computer Simulation
Cardiac Arrhythmias
Sudden Cardiac Death
Long QT Syndrome

Predictive multiscale in silico cardio-pharmacology

Clancy, C. E.

National Institutes of Health

9/1/158/31/20

Project: Research projectResearch Project--Cooperative Agreements

Computer Simulation
Pharmacology
Drug Interactions
Ion Channels
Pharmaceutical Preparations
Pharmacogenetics
Computer Simulation
Cardiac Arrhythmias
Pharmaceutical Preparations
Therapeutics

Research Output 1997 2018

Compartmentalized cAMP signaling associated with lipid raft and non-raft membrane domains in adult ventricular myocytes

Agarwal, S. R., Gratwohl, J., Cozad, M., Yang, P. C., Clancy, C. E. & Harvey, R. D., Apr 23 2018, In : Frontiers in Pharmacology. 9, APR, 332.

Research output: Contribution to journalArticle

Muscle Cells
Lipids
Membranes
Cell Membrane
Prostaglandin E Receptors
1 Citations

Determinants of isoform-specific gating kinetics of hERG1 channel: Combined experimental and simulation study

Perissinotti, L. L., De Biase, P. M., Guo, J., Yang, P. C., Lee, M. C., Clancy, C. E., Duff, H. J. & Noskov, S. Y., Apr 12 2018, In : Frontiers in Physiology. 9, APR, 207.

Research output: Contribution to journalArticle

Protein Isoforms
Action Potentials
Cardiac Electrophysiology
Long QT Syndrome
Markov Chains
1 Citations

Digging into lipid membrane permeation for cardiac ion channel blocker d-sotalol with all-atom simulations

DeMarco, K. R., Bekker, S., Clancy, C. E., Noskov, S. Y. & Vorobyov, I., Feb 1 2018, In : Frontiers in Pharmacology. 9, FEB, 26.

Research output: Contribution to journalArticle

Sotalol
Membrane Lipids
Ion Channels
Membranes
Pharmaceutical Preparations
1 Citations

Sex, drugs, and funky rhythms

Vorobyov, I. & Clancy, C. E., Apr 1 2018, In : Heart Rhythm. 15, 4, p. 485-486 2 p.

Research output: Contribution to journalEditorial

Pharmaceutical Preparations
8 Citations

A multiscale computational modelling approach predicts mechanisms of female sex risk in the setting of arousal-induced arrhythmias

Yang, P. C., Perissinotti, L. L., López-Redondo, F., Wang, Y., DeMarco, K. R., Jeng, M. T., Vorobyov, I., Harvey, R. D., Kurokawa, J., Noskov, S. Y. & Clancy, C. E., Jul 15 2017, In : Journal of Physiology. 595, 14, p. 4695-4723 29 p.

Research output: Contribution to journalArticle

Arousal
Cardiac Arrhythmias
Torsades de Pointes
Long QT Syndrome
Estrogens