Clare E Yellowley-Genetos, PhD; BSc (Hons)

Professor

  • 3270 Citations
  • 29 h-Index
19962019
If you made any changes in Pure, your changes will be visible here soon.

Research Output 1996 2019

  • 3270 Citations
  • 29 h-Index
  • 59 Article
  • 3 Chapter
  • 2 Conference contribution
  • 1 Review article
2019

Circulating progenitor cells and the expression of Cxcl12, Cxcr4 and angiopoietinlike 4 during wound healing in the murine ear

Yellowley-Genetos, C. E., Toupadakis, C. A., Vapniarsky Arzi, N. & Wong, A., Jan 1 2019, In : PloS one. 14, 9, e0222462.

Research output: Contribution to journalArticle

Open Access
tissue repair
Wound Healing
Cell Movement
Ear
stem cells
3 Citations (Scopus)

Hypoxia Signaling in the Skeleton: Implications for Bone Health

Yellowley-genetos, C. E. & Genetos, D. C., Feb 15 2019, In : Current Osteoporosis Reports. 17, 1, p. 26-35 10 p.

Research output: Contribution to journalReview article

Skeleton
Oxygen
Bone and Bones
Health
Osteocytes
2018
4 Citations (Scopus)

Age Dependence of Systemic Bone Loss and Recovery Following Femur Fracture in Mice

Emami, A. J., Toupadakis, C. A., Telek, S. M., Fyhrie, D. P., Yellowley-genetos, C. E. & Christiansen, B. A., Jan 1 2018, (Accepted/In press) In : Journal of Bone and Mineral Research.

Research output: Contribution to journalArticle

Femur
Bone and Bones
Bone Density
Femoral Fractures
Osteoclasts
5 Citations (Scopus)

Vhl deficiency in osteocytes produces high bone mass and hematopoietic defects

Loots, G. G., Robling, A. G., Chang, J. C., Murugesh, D. K., Bajwa, J., Carlisle, C., Manilay, J. O., Wong, A., Yellowley-genetos, C. E. & Genetos, D. C., Nov 1 2018, In : Bone. 116, p. 307-314 8 p.

Research output: Contribution to journalArticle

Osteocytes
Bone and Bones
Skeleton
Protein Isoforms
Myelopoiesis
2015

Analysis of a collagen II degradation protein C2C and a collagen II formation protein CP II in serumof Asian elephants (Elephas maximus)

Kilgallon, C. P., Larsen, R. S., Wong, A. & Yellowley-genetos, C. E., Mar 1 2015, In : Journal of Zoo and Wildlife Medicine. 46, 1, p. 146-149 4 p.

Research output: Contribution to journalArticle

Elephas maximus
Elephantidae
protein degradation
Proteolysis
collagen
6 Citations (Scopus)

Expression of angiopoietin-like protein 4 at the fracture site: Regulation by hypoxia and osteoblastic differentiation

Wilson, S. S., Wong, A., Toupadakis, C. A. & Yellowley-genetos, C. E., Sep 1 2015, In : Journal of Orthopaedic Research. 33, 9, p. 1364-1373 10 p.

Research output: Contribution to journalArticle

Angiopoietins
Bony Callus
Osteoblasts
Messenger RNA
Osteogenesis
1 Citation (Scopus)

Parathyroid hormone regulation of hypoxia-inducible factor signaling in osteoblastic cells

Wong, A., Loots, G. G., Yellowley-genetos, C. E., Dosé, A. C. & Genetos, D. C., Dec 1 2015, In : Bone. 81, p. 97-103 7 p.

Research output: Contribution to journalArticle

Hypoxia-Inducible Factor 1
Parathyroid Hormone
Oxygen
Luciferases
Osteoblasts
2014
8 Citations (Scopus)

Effect of hypoxia on generation of neurospheres from adipose tissue-derived canine mesenchymal stromal cells

Chung, D. J., Wong, A., Hayashi, K. & Yellowley-genetos, C. E., Jan 2014, In : Veterinary Journal. 199, 1, p. 123-130 8 p.

Research output: Contribution to journalArticle

stromal cells
Mesenchymal Stromal Cells
Erythropoietin Receptors
adipose tissue
Canidae
14 Citations (Scopus)

Impaired osteoblast differentiation in annexin A2- And -A5-deficient cells

Genetos, D. C., Wong, A., Weber, T. J., Karin, N. J. & Yellowley-genetos, C. E., Sep 15 2014, In : PLoS One. 9, 9, e107482.

Research output: Contribution to journalArticle

Annexin A2
Annexins
osteoblasts
Annexin A5
Osteoblasts
9 Citations (Scopus)

Nestin expression in mesenchymal stromal cells: Regulation by hypoxia and osteogenesis

Wong, A., Ghassemi, E. & Yellowley-genetos, C. E., Aug 5 2014, In : BMC Veterinary Research. 10, 1, 173.

Research output: Contribution to journalArticle

Cell Hypoxia
Nestin
stromal cells
bone formation
Mesenchymal Stromal Cells
7 Citations (Scopus)

Remineralized bone matrix as a scaffold for bone tissue engineering

Soicher, M. A., Christiansen, B. A., Stover, S. M., Leach, J. K., Yellowley-genetos, C. E., Griffiths, L. G. & Fyhrie, D. P., Dec 1 2014, In : Journal of Biomedical Materials Research - Part A. 102, 12, p. 4480-4490 11 p.

Research output: Contribution to journalArticle

Scaffolds (biology)
Tissue engineering
Bone
Biocompatible Materials
Biomaterials
2013
5 Citations (Scopus)

Detection of bacterial DNA by PCR in dogs with stifle pathology

Bhandal, J., Hayashi, K., Kim, S. Y., Klein, M., Wong, A., Toupadakis, C. A., Muir, P. & Yellowley-genetos, C. E., Oct 2013, In : Veterinary Surgery. 42, 7, p. 814-818 5 p.

Research output: Contribution to journalArticle

Stifle
Bacterial DNA
cranial cruciate ligament
Anterior Cruciate Ligament
Dogs
31 Citations (Scopus)

Mobilization of endogenous stem cell populations enhances fracture healing in a murine femoral fracture model

Toupadakis, C. A., Granick, J. L., Sagy, M., Wong, A., Ghassemi, E., Chung, D. J., Borjesson, D. L. & Yellowley-genetos, C. E., Sep 2013, In : Cytotherapy. 15, 9, p. 1136-1147 12 p.

Research output: Contribution to journalArticle

Hematopoietic Stem Cell Mobilization
Fracture Healing
Femoral Fractures
Stem Cells
Hematopoietic Stem Cells
2012
46 Citations (Scopus)

Long-term administration of AMD3100, an antagonist of SDF-1/CXCR4 signaling, alters fracture repair

Toupadakis, C. A., Wong, A., Genetos, D. C., Chung, D. J., Murugesh, D., Anderson, M. J., Loots, G. G., Christiansen, B. A., Kapatkin, A. & Yellowley-genetos, C. E., Nov 2012, In : Journal of Orthopaedic Research. 30, 11, p. 1853-1859 7 p.

Research output: Contribution to journalArticle

Stem Cells
Fracture Healing
Hyaline Cartilage
Bone and Bones
Euthanasia
43 Citations (Scopus)

Osteogenic proliferation and differentiation of canine bone marrow and adipose tissue derived mesenchymal stromal cells and the influence of hypoxia

Chung, D. J., Hayashi, K., Toupadakis, C. A., Wong, A. & Yellowley-genetos, C. E., Feb 2012, In : Research in Veterinary Science. 92, 1, p. 66-75 10 p.

Research output: Contribution to journalArticle

Cell Hypoxia
stromal cells
Mesenchymal Stromal Cells
bone marrow
adipose tissue

The biology of stem cells and their role in tissue repair

Yellowley-genetos, C. E., Oct 2012, In : Journal of Equine Veterinary Science. 32, 10, p. 661-662 2 p.

Research output: Contribution to journalArticle

tissue repair
stem cells
Stem Cells
Biological Sciences
2011
47 Citations (Scopus)

Hypoxic regulation of mesenchymal stem cell migration: The role of RhoA and HIF-1α

Raheja, L. F., Genetos, D. C., Wong, A. & Yellowley-genetos, C. E., Oct 1 2011, In : Cell Biology International. 35, 10, p. 981-989 9 p.

Research output: Contribution to journalArticle

Hypoxia-Inducible Factor 1
Mesenchymal Stromal Cells
Cell Movement
Oxygen
GTP Phosphohydrolases
43 Citations (Scopus)

Prostaglandin E2 signals through PTGER2 to regulate sclerostin expression

Genetos, D. C., Yellowley-genetos, C. E. & Loots, G. G., 2011, In : PLoS One. 6, 3, e17772.

Research output: Contribution to journalArticle

Dinoprostone
prostaglandins
Bone
Wnt Signaling Pathway
bones
9 Citations (Scopus)

Regulation of tenascin expression in bone

Morgan, J. M., Wong, A., Yellowley-genetos, C. E. & Genetos, D. C., Nov 2011, In : Journal of Cellular Biochemistry. 112, 11, p. 3354-3363 10 p.

Research output: Contribution to journalArticle

Tenascin
Bone
Bone and Bones
Bone Morphogenetic Proteins
Osteoblasts
1 Citation (Scopus)

Src is sufficient, but not necessary, for osteopontin induction in osteoblasts

Morgan, J. M., Wong, A., Genetos, D. C. & Yellowley-genetos, C. E., 2011, In : Biorheology. 48, 1, p. 65-74 10 p.

Research output: Contribution to journalArticle

Osteopontin
Osteoblasts
Phosphorylation
Bone and Bones
Focal Adhesions
8 Citations (Scopus)
stromal cells
Articular Cartilage
thighs
Thigh
Mesenchymal Stromal Cells
2010
120 Citations (Scopus)
umbilical cord
Umbilical Cord
Mesenchymal Stromal Cells
Fetal Blood
bone marrow
67 Citations (Scopus)

Hypoxia decreases sclerostin expression and increases Wnt signaling in osteoblasts

Genetos, D. C., Toupadakis, C. A., Raheja, L. F., Wong, A., Papanicolaou, S. E., Fyhrie, D. P., Loots, G. G. & Yellowley-genetos, C. E., May 15 2010, In : Journal of Cellular Biochemistry. 110, 2, p. 457-467 11 p.

Research output: Contribution to journalArticle

Osteoblasts
Catenins
Transcription
Vascular Endothelial Growth Factor A
Bone
30 Citations (Scopus)

Hypoxia increases Annexin A2 expression in osteoblastic cells via VEGF and ERK

Genetos, D. C., Wong, A., Watari, S. & Yellowley-genetos, C. E., Dec 2010, In : Bone. 47, 6, p. 1013-1019 7 p.

Research output: Contribution to journalArticle

Annexin A2
Vascular Endothelial Growth Factor A
Osteoblasts
Hypoxia
Neuropilin-2
41 Citations (Scopus)
Stem cells
Cell culture
Stem Cells
Oxygen
Cultured Cells
9 Citations (Scopus)

Prostaglandin expression profile in hypoxic osteoblastic cells

Lee, C. M., Genetos, D. C., Wong, A. & Yellowley-genetos, C. E., Jan 2010, In : Journal of Bone and Mineral Metabolism. 28, 1, p. 8-16 9 p.

Research output: Contribution to journalArticle

Prostaglandins
Dinoprostone
Bone and Bones
Cell Hypoxia
Oxygen
21 Citations (Scopus)
Matrix Metalloproteinase Inhibitors
Matrix Metalloproteinases
Mesenchymal Stromal Cells
Oxygen
Matrix Metalloproteinase 13
2009
15 Citations (Scopus)

HIF-1α regulates hypoxia-induced EP1 expression in osteoblastic cells

Genetos, D. C., Lee, C. M., Wong, A. & Yellowley-genetos, C. E., May 15 2009, In : Journal of Cellular Biochemistry. 107, 2, p. 233-239 7 p.

Research output: Contribution to journalArticle

Hypoxia-Inducible Factor 1
Small Interfering RNA
Bone
Repair
Bone Development
2008
47 Citations (Scopus)

Hypoxic osteocytes recruit human MSCs through an OPN/CD44-mediated pathway

Raheja, L. F., Genetos, D. C. & Yellowley-genetos, C. E., Feb 22 2008, In : Biochemical and Biophysical Research Communications. 366, 4, p. 1061-1066 6 p.

Research output: Contribution to journalArticle

Osteocytes
Osteopontin
Repair
Chemotactic Factors
Conditioned Culture Medium
2007
13 Citations (Scopus)

Adenosine inhibition of lipopolysaccharide-induced interleukin-6 secretion by the osteoblastic cell line MG-63

Russell, J. M., Stephenson, G. S., Yellowley-genetos, C. E. & Benton, H. P., Oct 2007, In : Calcified Tissue International. 81, 4, p. 316-326 11 p.

Research output: Contribution to journalArticle

Adenosine
Lipopolysaccharides
Interleukin-6
Adenosine-5'-(N-ethylcarboxamide)
Cell Line
14 Citations (Scopus)

DNA microarray analysis reveals a role for lysophosphatidic acid in the regulation of anti-inflammatory genes in MC3T3-E1 cells

Waters, K. M., Tan, R., Genetos, D. C., Verma, S., Yellowley-genetos, C. E. & Karin, N. J., Nov 2007, In : Bone. 41, 5, p. 833-841 9 p.

Research output: Contribution to journalArticle

Microarray Analysis
Oligonucleotide Array Sequence Analysis
Anti-Inflammatory Agents
Genes
Lipids
21 Citations (Scopus)

Hypoxia regulates PGE2 release and EP1 receptor expression in osteoblastic cells

Lee, C. M., Genetos, D. C., You, Z. & Yellowley-genetos, C. E., Jul 2007, In : Journal of Cellular Physiology. 212, 1, p. 182-188 7 p.

Research output: Contribution to journalArticle

Dinoprostone
Bone
Bone and Bones
Response Elements
Cultured Cells
193 Citations (Scopus)

Oscillating fluid flow activation of gap junction hemichannels induces ATP release from MLO-Y4 osteocytes

Genetos, D. C., Kephart, C. J., Zhang, Y., Yellowley-genetos, C. E. & Donahue, H. J., Jul 2007, In : Journal of Cellular Physiology. 212, 1, p. 207-214 8 p.

Research output: Contribution to journalArticle

Osteocytes
Gap Junctions
Osteoblasts
Flow of fluids
Adenosine Triphosphate
2006
107 Citations (Scopus)

Oscillatory fluid flow-induced shear stress decreases osteoclastogenesis through RANKL and OPG signaling

Kim, C. H., You, L., Yellowley-genetos, C. E. & Jacobs, C. R., Nov 2006, In : Bone. 39, 5, p. 1043-1047 5 p.

Research output: Contribution to journalArticle

Osteoprotegerin
Osteoclasts
Osteogenesis
Bone Remodeling
RANK Ligand
2005
91 Citations (Scopus)

Effects of short-term recovery periods on fluid-induced signaling in osteoblastic cells

Batra, N. N., Li, Y. J., Yellowley-genetos, C. E., You, L., Malone, A. M., Chi, H. K. & Jacobs, C. R., Sep 2005, In : Journal of Biomechanics. 38, 9, p. 1909-1917 9 p.

Research output: Contribution to journalArticle

Bone
Flow of fluids
Recovery
Fluids
Calcium
2004
29 Citations (Scopus)

Annexin V disruption impairs mechanically induced calcium signaling in osteoblastic cells

Haut Donahue, T. L., Genetos, D. C., Jacobs, C. R., Donahue, H. J. & Yellowley-genetos, C. E., Sep 2004, In : Bone. 35, 3, p. 656-663 8 p.

Research output: Contribution to journalArticle

Calcium Signaling
Annexin A5
Bone and Bones
Osteoblasts
Ion Channels
11 Citations (Scopus)

Cycle number and waveform of fluid flow affect bovine articular chondrocytes

Edlich, M., Yellowley-genetos, C. E., Jacobs, C. R. & Donahue, H. J., 2004, In : Biorheology. 41, 3-4, p. 315-322 8 p.

Research output: Contribution to journalArticle

Chondrocytes
Joints
Tooth
Articular Cartilage
Fura-2
190 Citations (Scopus)

Oscillatory fluid flow affects human marrow stromal cell proliferation and differentiation

Li, Y. J., Batra, N. N., You, L., Meier, S. C., Coe, I. A., Yellowley-genetos, C. E. & Jacobs, C. R., Nov 2004, In : Journal of Orthopaedic Research. 22, 6, p. 1283-1289 7 p.

Research output: Contribution to journalArticle

Stromal Cells
Cell Differentiation
Bone Marrow
Cell Proliferation
Osteoblasts
2003
79 Citations (Scopus)

Fluid flow induced PGE2 release by bone cells is reduced by glycocalyx degradation whereas calcium signals are not

Reilly, G. C., Haut, T. R., Yellowley-genetos, C. E., Donahue, H. J. & Jacobs, C. R., 2003, In : Biorheology. 40, 6, p. 591-603 13 p.

Research output: Contribution to journalArticle

Glycocalyx
Dinoprostone
Calcium
Bone and Bones
Hyaluronoglucosaminidase
70 Citations (Scopus)

Fluid flow-induced prostaglandin E2 response of osteoblastic ROS 17/2.8 cells is gap junction-mediated and independent of cytosolic calcium

Saunders, M. M., You, J., Zhou, Z., Li, Z., Yellowley-genetos, C. E., Kunze, E. L., Jacobs, C. R. & Donahue, H. J., Apr 1 2003, In : Bone. 32, 4, p. 350-356 7 p.

Research output: Contribution to journalArticle

Gap Junctions
Dinoprostone
Calcium
Bone and Bones
Connexin 43
18 Citations (Scopus)

Increases in Cytosolic Calcium, but not Fluid Flow, Affect Aggrecan mRNA Levels in Articular Chondrocytes

Alford, A. I., Yellowley-genetos, C. E., Jacobs, C. R. & Donahue, H. J., Dec 1 2003, In : Journal of Cellular Biochemistry. 90, 5, p. 938-944 7 p.

Research output: Contribution to journalArticle

Aggrecans
Chondrocytes
Ionomycin
Flow of fluids
Joints
84 Citations (Scopus)

Mechanosensitivity of bone cells to oscillating fluid flow induced shear stress may be modulated by chemotransport

Donahue, T. L. H., Haut, T. R., Yellowley-genetos, C. E., Donahue, H. J. & Jacobs, C. R., Sep 1 2003, In : Journal of Biomechanics. 36, 9, p. 1363-1371 9 p.

Research output: Contribution to journalArticle

Shear stress
Flow of fluids
Bone
Bone and Bones
Dinoprostone
2002
58 Citations (Scopus)

Effects of cell swelling on intracellular calcium and membrane currents in bovine articular chondrocytes

Yellowley-genetos, C. E., Hancox, J. C. & Donahue, H. J., 2002, In : Journal of Cellular Biochemistry. 86, 2, p. 290-301 12 p.

Research output: Contribution to journalArticle

Intracellular Membranes
Chondrocytes
Swelling
Joints
Calcium
26 Citations (Scopus)

Intracellular calcium changes in rat aortic smooth muscle cells in response to fluid flow

Sharma, R., Yellowley-genetos, C. E., Civelek, M., Ainslie, K., Hodgson, L., Tarbell, J. M. & Donahue, H. J., 2002, In : Annals of Biomedical Engineering. 30, 3, p. 371-378 8 p.

Research output: Contribution to journalArticle

Muscle
Rats
Shear stress
Flow of fluids
Calcium
2001

An overview of oscialltory fluid flow as a potent loading-induced physical signal in bone cells

Jacobs, C. R., You, J., Reilly, G., Saunders, M. M., Kurokouchi, K., Yellowley-genetos, C. E. & Donahue, H. J., 2001, American Society of Mechanical Engineers, Bioengineering Division (Publication) BED. Kamm, R. D., Schmid-Schoenbein, G. W., Atesian, G. A. & Hefzy, M. S. (eds.). Vol. 50. p. 339-340 2 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Steady flow
Flow of fluids
Bone
Oscillating flow
Gadolinium
45 Citations (Scopus)

Connexin expression by alveolar epithelial cells is regulated by extracellular matrix

Guo, Y., Martinez-Williams, C., Yellowley-genetos, C. E., Donahue, H. J. & Rannels, D. E., Feb 2001, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 280, 2 24-2

Research output: Contribution to journalArticle

Alveolar Epithelial Cells
Connexin 43
Connexins
Extracellular Matrix
Gap Junctions
39 Citations (Scopus)

Oscillating fluid flow regulates cytosolic calcium concentration in bovine articular chondrocytes

Edlich, M., Yellowley-genetos, C. E., Jacobs, C. R. & Donahue, H. J., Jan 2001, In : Journal of Biomechanics. 34, 1, p. 59-65 7 p.

Research output: Contribution to journalArticle

Chondrocytes
Flow of fluids
Calcium
Joints
Flow rate

Oscillatory flow-induced prostaglandin E2 release involves protein kinase a and cyclooxygenase-2 in MC3T3-E1 osteoblasts

You, J., Saunders, M. M., Yellowley-genetos, C. E., Donahue, H. J. & Jacobs, C. R., 2001, American Society of Mechanical Engineers, Bioengineering Division (Publication) BED. Kamm, R. D., Schmid-Schoenbein, G. W., Atesian, G. A. & Hefzy, M. S. (eds.). Vol. 50. p. 163-164 2 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Osteoblasts
Oscillating flow
Proteins
Bone
Prostaglandin-Endoperoxide Synthases
307 Citations (Scopus)

Osteopontin Gene Regulation by Oscillatory Fluid Flow via Intracellular Calcium Mobilization and Activation of Mitogen-activated Protein Kinase in MC3T3-E1 Osteoblasts

You, J., Reilly, G. C., Zhen, X., Yellowley-genetos, C. E., Chen, Q., Donahue, H. J. & Jacobs, C. R., Apr 20 2001, In : Journal of Biological Chemistry. 276, 16, p. 13365-13371 7 p.

Research output: Contribution to journalArticle

Osteopontin
Osteoblasts
Mitogen-Activated Protein Kinases
Gene expression
Flow of fluids
2000
15 Citations (Scopus)

Analysis of time-varying biological data using rainflow cycle counting

Jacobs, C. R., Yellowley-genetos, C. E., Nelson, D. V. & Donahue, H. J., 2000, In : Computer Methods in Biomechanics and Biomedical Engineering. 3, 1, p. 31-40 10 p.

Research output: Contribution to journalArticle

Random errors
Fast Fourier transforms
Shear stress
Calcium
Automation