Christopher Bowlus, MD

Kuo, A., Gomel, R., Safer, R., Lindor, K. D., Everson, G. T. & Bowlus, C., Jun 1 2019, In : Clinical Gastroenterology and Hepatology. 17, 7, p. 1372-1378 7 p.

Research output: Contribution to journal › Article

Sclerosing Cholangitis

Registries

Demography

Patient Reported Outcome Measures

Databases

Epigenomic signatures in liver and blood of Wilson disease patients include hypermethylation of liver-specific enhancers

Mordaunt, C. E., Kieffer, D. A., Shibata, N. M., Członkowska, A., Litwin, T., Weiss, K. H., Zhu, Y., Bowlus, C., Sarkar, S., Cooper, S., Wan, Y-J. Y., Ali, M. R., LaSalle, J. M. & Medici, V., Jan 1 2019, In : Epigenetics and Chromatin. 12, 1, 0255.

Research output: Contribution to journal › Article

Hepatolenticular Degeneration

Hematologic Diseases

Epigenomics

Liver

Genome

1 Citation (Scopus)

Long-term efficacy and safety of obeticholic acid for patients with primary biliary cholangitis: 3-year results of an international open-label extension study

Trauner, M., Nevens, F., Shiffman, M. L., Drenth, J. P. H., Bowlus, C., Vargas, V., Andreone, P., Hirschfield, G. M., Pencek, R., Malecha, E. S., MacConell, L. & Shapiro, D., Jun 1 2019, In : The Lancet Gastroenterology and Hepatology. 4, 6, p. 445-453 9 p.

Research output: Contribution to journal › Article

Cholangitis

Safety

Bilirubin

Ursodeoxycholic Acid

Alkaline Phosphatase

RARβ acts as both an upstream regulator and downstream effector of miR-22, which epigenetically regulates NUR77 to induce apoptosis of colon cancer cells

Hu, Y., French, S. W., Chau, T., Liu, H. X., Sheng, L., Wei, F., Stondell, J. L., Garcia, J. C., Du, Y., Bowlus, C. & Wan, Y-J. Y., Feb 1 2019, In : FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 33, 2, p. 2314-2326 13 p.

Research output: Contribution to journal › Article

MicroRNAs

Colonic Neoplasms

Cells

Apoptosis

Histone Deacetylase Inhibitors

7 Citations (Scopus)

Simtuzumab for Primary Sclerosing Cholangitis: Phase 2 Study Results With Insights on the Natural History of the Disease

for the GS-US-321-0102 Investigators, Jan 1 2019, (Accepted/In press) In : Hepatology.

Research output: Contribution to journal › Article

Sclerosing Cholangitis

Protein-Lysine 6-Oxidase

Fibrosis

Placebos

Confidence Intervals