Charles DeCarli, MD

Professor

  • 48224 Citations
  • 107 h-Index
1981 …2020

Research output per year

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Research Output

2020

An IL-18-centered inflammatory network as a biomarker for cerebral white matter injury

Altendahl, M., Maillard, P., Harvey, D., Cotter, D., Walters, S., Wolf, A., Singh, B., Kakarla, V., Azizkhanian, I., Sheth, S. A., Xiao, G., Fox, E., You, M., Leng, M., Elashoff, D., Kramer, J. H., Decarli, C., Elahi, F. & Hinman, J. D., Jan 1 2020, In : PloS one. 15, 1, e0227835.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Association Between Central Blood Pressure and Subclinical Cerebrovascular Disease in Older Adults

Matsumoto, K., Jin, Z., Homma, S., Elkind, M. S. V., Rundek, T., Mannina, C., Lee, T. C., Yoshita, M., DeCarli, C., Wright, C. B., Sacco, R. L. & Di Tullio, M. R., Feb 1 2020, In : Hypertension (Dallas, Tex. : 1979). 75, 2, p. 580-587 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

Association of CD14 with incident dementia and markers of brain aging and injury

Pase, M. P., Himali, J. J., Beiser, A. S., DeCarli, C., McGrath, E. R., Satizabal, C. L., Aparicio, H. J., Adams, H. H. H., Reiner, A. P., Longstreth, W. T., Fornage, M., Tracy, R. P., Lopez, O., Psaty, B. M., Levy, D., Seshadri, S. & Bis, J. C., Jan 21 2020, In : Neurology. 94, 3, p. e254-e266

Research output: Contribution to journalArticle

Challenges and Opportunities with Causal Discovery Algorithms: Application to Alzheimer’s Pathophysiology

the Alzheimer’s Disease Neuroimaging Initiative, Dec 1 2020, In : Scientific reports. 10, 1, 2975.

Research output: Contribution to journalArticle

Open Access

Circulating ceramide ratios and risk of vascular brain aging and dementia

McGrath, E. R., Himali, J. J., Xanthakis, V., Duncan, M. S., Schaffer, J. E., Ory, D. S., Peterson, L. R., DeCarli, C., Pase, M. P., Satizabal, C. L., Vasan, R. S., Beiser, A. S. & Seshadri, S., Jan 1 2020, (Accepted/In press) In : Annals of Clinical and Translational Neurology.

Research output: Contribution to journalArticle

Open Access

Cognitive reserve and rate of change in Alzheimer's and cerebrovascular disease biomarkers among cognitively normal individuals

Pettigrew, C., Soldan, A., Zhu, Y., Cai, Q., Wang, M. C., Moghekar, A., Miller, M. I., Singh, B., Martinez, O., Fletcher, E., DeCarli, C. & Albert, M., Jan 1 2020, (Accepted/In press) In : Neurobiology of aging.

Research output: Contribution to journalArticle

Correction to: A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer’s disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity (Acta Neuropathologica, (2019), 138, 2, (237-250), 10.1007/s00401-019-02026-8)

EADB (Alzheimer Disease European DNA biobank), IFGC (International FTD-Genomics Consortium), IPDGC (The International Parkinson Disease Genomics Consortium), RiMod-FTD (Risk and Modifying factors in Fronto-Temporal Dementia), Netherlands Brain Bank (NBB), The GIFT (Genetic Investigation in Frontotemporal Dementia and Alzheimer’s Disease) Study Group & DESGESCO (Dementia Genetics Spanish Consortium), Jan 1 2020, (Accepted/In press) In : Acta Neuropathologica.

Research output: Contribution to journalComment/debate

Open Access

Diabetes, cognitive decline, and mild cognitive impairment among diverse Hispanics/ Latinos: Study of Latinos–Investigation of neurocognitive aging results (HCHS/SOL)

González, H. M., Tarraf, W., González, K. A., Fornage, M., Zeng, D., Gallo, L. C., Talavera, G. A., Daviglus, M. L., Lipton, R. B., Kaplan, R., Ramos, A. R., Lamar, M., Cai, J., DeCarli, C. & Schneiderman, N., May 1 2020, In : Diabetes Care. 43, 5, p. 1111-1117 7 p.

Research output: Contribution to journalArticle

Exceptionally low likelihood of Alzheimer’s dementia in APOE2 homozygotes from a 5,000-person neuropathological study

The Alzheimer’s Disease Genetics Consortium, Dec 1 2020, In : Nature communications. 11, 1, 667.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

FAM222A encodes a protein which accumulates in plaques in Alzheimer’s disease

The Alzheimer Disease Neuroimaging Initiative, Dec 1 2020, In : Nature communications. 11, 1, 411.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Flavonoid Intake and MRI Markers of Brain Health in the Framingham Offspring Cohort

Shishtar, E., Rogers, G. T., Blumberg, J. B., Au, R., DeCarli, C. & Jacques, P. F., Jun 1 2020, In : The Journal of nutrition. 150, 6, p. 1545-1553 9 p.

Research output: Contribution to journalArticle

Open Access

Functional brain architecture is associated with the rate of tau accumulation in Alzheimer’s disease

Alzheimer’S Disease Neuroimaging Initiative (Adni), Dec 1 2020, In : Nature communications. 11, 1, 347.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

The genetic architecture of the human cerebral cortex

Enhancing NeuroImaging Genetics through Meta-Analysis Consortium (ENIGMA)-Genetics working group, Mar 20 2020, In : Science. 367, 6484, aay6690.

Research output: Contribution to journalArticle

19 Scopus citations

White matter hyperintensities and CSF Alzheimer disease biomarkers in preclinical Alzheimer disease

BIOCARD Research Team, Mar 3 2020, In : Neurology. 94, 9, p. e950-e960

Research output: Contribution to journalArticle

2 Scopus citations
2019

A blood-based signature of cerebrospinal fluid Aβ 1–42 status

Alzheimer’s Disease Metabolomics Consortium & Alzheimer’s Disease Neuroimaging Initiative, Dec 1 2019, In : Scientific Reports. 9, 1, 4163.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

A comparison of automated segmentation and manual tracing in estimating hippocampal volume in ischemic stroke and healthy control participants

Khlif, M. S., Egorova, N., Werden, E., Redolfi, A., Bocardi, M., DeCarli, C., Fletcher, E., Singh, B., Li, Q., Bird, L. & Brodtmann, A., Jan 1 2019, (Accepted/In press) In : NeuroImage: Clinical. 101581.

Research output: Contribution to journalArticle

5 Scopus citations

A genome-wide association study identifies genetic loci associated with specific lobar brain volumes

van der Lee, S. J., Knol, M. J., Chauhan, G., Satizabal, C. L., Smith, A. V., Hofer, E., Bis, J. C., Hibar, D. P., Hilal, S., van den Akker, E. B., Arfanakis, K., Bernard, M., Yanek, L. R., Amin, N., Crivello, F., Cheung, J. W., Harris, T. B., Saba, Y., Lopez, O. L., Li, S. & 42 others, van der Grond, J., Yu, L., Paus, T., Roshchupkin, G. V., Amouyel, P., Jahanshad, N., Taylor, K. D., Yang, Q., Mathias, R. A., Boehringer, S., Mazoyer, B., Rice, K., Cheng, C. Y., Maillard, P., van Heemst, D., Wong, T. Y., Niessen, W. J., Beiser, A. S., Beekman, M., Zhao, W., Nyquist, P. A., Chen, C., Launer, L. J., Psaty, B. M., Ikram, M. K., Vernooij, M. W., Schmidt, H., Pausova, Z., Becker, D. M., De Jager, P. L., Thompson, P. M., van Duijn, C. M., Bennett, D. A., Slagboom, P. E., Schmidt, R., Longstreth, W. T., Ikram, M. A., Seshadri, S., Debette, S., Gudnason, V., Adams, H. H. H. & DeCarli, C., Dec 1 2019, In : Communications Biology. 2, 1, 285.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer’s disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity

DESGESCO (Dementia Genetics Spanish Consortium), EADB (Alzheimer Disease European DNA biobank), EADB (Alzheimer Disease European DNA biobank), IFGC (International FTD-Genomics Consortium), IPDGC (The International Parkinson Disease Genomics Consortium), IPDGC (The International Parkinson Disease Genomics Consortium), RiMod-FTD (Risk and Modifying factors in Fronto-Temporal Dementia), Netherlands Brain Bank (NBB) & The GIFT (Genetic Investigation in Frontotemporal Dementia and Alzheimer’s Disease) Study Group, Jan 1 2019, In : Acta Neuropathologica.

Research output: Contribution to journalArticle

Open Access
15 Scopus citations

A Novel Joint Brain Network Analysis Using Longitudinal Alzheimer’s Disease Data

the Alzheimer’s Disease Neuroimaging Initiative, Dec 1 2019, In : Scientific reports. 9, 1, 19589.

Research output: Contribution to journalArticle

Open Access

Application of an amyloid and tau classification system in subcortical vascular cognitive impairment patients

Jang, H., Kim, H. J., Park, S., Park, Y. H., Choe, Y., Cho, H., Lyoo, C. H., Yoon, U., Lee, J. S., Kim, Y., Kim, S. J., Kim, J. P., Jung, Y. H., Ryu, Y. H., Choi, J. Y., Moon, S. H., Seong, J. K., DeCarli, C., Weiner, M. W., Lockhart, S. N. & 3 others, Cho, S. H., Na, D. L. & Seo, S. W., Jan 1 2019, (Accepted/In press) In : European Journal of Nuclear Medicine and Molecular Imaging.

Research output: Contribution to journalArticle

1 Scopus citations

Assessment of Plasma Total Tau Level as a Predictive Biomarker for Dementia and Related Endophenotypes

Pase, M. P., Beiser, A. S., Himali, J. J., Satizabal, C. L., Aparicio, H. J., DeCarli, C., Chêne, G., Dufouil, C. & Seshadri, S., Jan 1 2019, In : JAMA neurology.

Research output: Contribution to journalArticle

19 Scopus citations

Association of Accelerometer-Measured Light-Intensity Physical Activity With Brain Volume: The Framingham Heart Study

Spartano, N. L., Davis-Plourde, K. L., Himali, J. J., Andersson, C., Pase, M. P., Maillard, P., DeCarli, C., Murabito, J. M., Beiser, A. S., Vasan, R. S. & Seshadri, S., Apr 5 2019, In : JAMA network open. 2, 4, p. e192745

Research output: Contribution to journalArticle

Open Access
17 Scopus citations

Association of Plasma Amylin Concentration With Alzheimer Disease and Brain Structure in Older Adults

Zhu, H., Tao, Q., Ang, T. F. A., Massaro, J., Gan, Q., Salim, S., Zhu, R. Y., Kolachalama, V. B., Zhang, X., Devine, S., Auerbach, S. H., DeCarli, C., Au, R. & Qiu, W. Q., Aug 2 2019, In : JAMA Network Open. 2, 8, p. e199826

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Author Correction: Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing (Nature Genetics, (2019), 51, 3, (414-430), 10.1038/s41588-019-0358-2)

Alzheimer Disease Genetics Consortium (ADGC), The European Alzheimer’s Disease Initiative (EADI), Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium (CHARGE) & Genetic and Environmental Risk in AD/Defining Genetic, Polygenic and Environmental Risk for Alzheimer’s Disease Consortium (GERAD/PERADES), Sep 1 2019, In : Nature Genetics. 51, 9, p. 1423-1424 2 p.

Research output: Contribution to journalComment/debate

Open Access

Birth in high infant mortality states and dementia risk in a cohort of elderly African American and white health care members

Gilsanz, P., RoseMayeda, E., Glymour, M. M., Quesenberry, C. P., Mungas, D. M., DeCarli, C. & Whitmer, R., Jan 1 2019, In : Alzheimer Disease and Associated Disorders. 33, 1, p. 1-6 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

Cardiovascular disease risk factor burden and cognition: Implications of ethnic diversity within the Hispanic Community Health Study/ Study of Latinos

Lamar, M., Durazo-Arvizu, R. A., Sachdeva, S., Pirzada, A., Perreira, K. M., Rundek, T., Gallo, L. C., Grober, E., DeCarli, C., Lipton, R. B., Tarraf, W., González, H. M. & Daviglus, M. L., Apr 1 2019, In : PloS one. 14, 4, e0215378.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Cerebral white matter free water: A sensitive biomarker of cognition and function

Maillard, P., Fletcher, E., Singh, B., Martinez, O., Johnson, D. K., Olichney, J. M., Farias, S. T. & DeCarli, C., May 7 2019, In : Neurology. 92, 19, p. e2221-e2231

Research output: Contribution to journalArticle

2 Scopus citations

Circulating IGFBP-2: a novel biomarker for incident dementia

McGrath, E. R., Himali, J. J., Levy, D., Conner, S. C., DeCarli, C. S., Pase, M. P., Courchesne, P., Satizabal, C. L., Vasan, R. S., Beiser, A. S. & Seshadri, S., Sep 1 2019, In : Annals of Clinical and Translational Neurology. 6, 9, p. 1659-1670 12 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Distribution of cerebral microbleeds in the East and West: Individual participant meta-analysis

Yakushiji, Y., Wilson, D., Ambler, G., Charidimou, A., Beiser, A., Van Buchem, M. A., DeCarli, C., Ding, D., Gudnason, V., Hara, H., Imaizumi, T., Kohara, K., Kwon, H. M., Launer, L. J., Mok, V., Phan, T., Preis, S. R., Romero, J. R., Seshadri, S., Srikanth, V. & 7 others, Takashima, Y., Tsushima, Y., Wang, Z., Wolf, P. A., Xiong, Y., Yamaguchi, S. & Werring, D. J., Mar 5 2019, In : Neurology. 92, 10, p. E1086-E1097

Research output: Contribution to journalArticle

8 Scopus citations

Extravascular fibrinogen in the white matter of Alzheimer’s disease and normal aged brains: implications for fibrinogen as a biomarker for Alzheimer’s disease

McAleese, K. E., Graham, S., Dey, M., Walker, L., Erskine, D., Johnson, M., Johnston, E., Thomas, A. J., McKeith, I. G., DeCarli, C. & Attems, J., Jan 1 2019, In : Brain Pathology.

Research output: Contribution to journalArticle

2 Scopus citations

Frequency of the TREM2 R47H Variant in Various Neurodegenerative Disorders

Ayer, A. H., Wojta, K., Ramos, E. M., Dokuru, D., Chen, J. A., Karydas, A. M., Papatriantafyllou, J. D., Agiomyrgiannakis, D., Kamtsadeli, V., Tsinia, N., Sali, D., Gylys, K. H., Agosta, F., Filippi, M., Small, G. W., Bennett, D. A., Gearing, M., Juncos, J. L., Kramer, J., Lee, S. E. & 13 others, Yokoyama, J. S., Mendez, M. F., Chui, H., Zarow, C., Ringman, J. M., Kilic, U., Babacan-Yildiz, G., Levey, A., Decarli, C. S., Cotman, C. W., Boxer, A. L., Miller, B. L. & Coppola, G., Jan 1 2019, In : Alzheimer disease and associated disorders. 33, 4, p. 327-330 4 p.

Research output: Contribution to journalArticle

1 Scopus citations

Full exploitation of high dimensionality in brain imaging: The JPND working group statement and findings

Adams, H. H. H., Roshchupkin, G. V., DeCarli, C., Franke, B., Grabe, H. J., Habes, M., Jahanshad, N., Medland, S. E., Niessen, W., Satizabal, C. L., Schmidt, R., Seshadri, S., Teumer, A., Thompson, P. M., Vernooij, M. W., Wittfeld, K. & Ikram, M. A., Dec 1 2019, In : Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 11, p. 286-290 5 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting

Chauhan, G., Adams, H. H. H., Satizabal, C. L., Bis, J. C., Teumer, A., Sargurupremraj, M., Hofer, E., Trompet, S., Hilal, S., Smith, A. V., Jian, X., Malik, R., Traylor, M., Pulit, S. L., Amouyel, P., Mazoyer, B., Zhu, Y. C., Kaffashian, S., Schilling, S., Beecham, G. W. & 130 others, Montine, T. J., Schellenberg, G. D., Kjartansson, O., Guonason, V., Knopman, D. S., Griswold, M. E., Windham, B. G., Gottesman, R. F., Mosley, T. H., Schmidt, R., Saba, Y., Schmidt, H., Takeuchi, F., Yamaguchi, S., Nabika, T., Kato, N., Rajan, K., Aggarwal, N. T., De Jager, P. L., Evans, D. A., Psaty, B. M., Rotter, J. I., Rice, K., Lopez, O. L., Liao, J., Chen, C., Cheng, C. Y., Wong, T. Y., Ikram, M. K., Van Der Lee, J. S., Amin, N., Chouraki, V., DeStefano, A. L., Aparicio, H. J., Romero, J. R., Maillard, P., DeCarli, C., Wardlaw, J. M., Del Valdes Hernandez, M. C., Luciano, M., Liewald, D., Deary, I. J., Starr, J. M., Bastin, M. E., Maniega, S. M., Slagboom, P. E., Beekman, M., Deelen, J., Uh, H. W., Lemmens, R., Brodaty, H., Wright, M. J., Ames, D., Boncoraglio, G. B., Hopewell, J. C., Beecham, A. H., Blanton, S. H., Wright, C. B., Sacco, R. L., Wen, W., Thalamuthu, A., Armstrong, N. J., Chong, E., Schofield, P. R., Kwok, J. B., Van der Grond, J., Stott, D. J., Ford, I., Jukema, J. W., Vernooij, M. W., Hofman, A., Uitterlinden, A. G., Van der Lugt, A., Wittfeld, K., Grabe, H. J., Hosten, N., Von Sarnowski, B., Volker, U., Levi, C., Jimenez-Conde, J., Sharma, P., Sudlow, C. L. M., Rosand, J., Woo, D., Cole, J. W., Meschia, J. F., Slowik, A., Thijs, V., Lindgren, A., Melander, O., Grewal, R. P., Rundek, T., Rexrode, K., Rothwell, P. M., Arnett, D. K., Jern, C., Johnson, J. A., Benavente, O. R., Wasssertheil-Smoller, S., Lee, J. M., Wong, Q., Mitchell, B. D., Rich, S. S., McArdle, P. F., Geerlings, M. I., Van der Graaf, Y., De Bakker, P. I. W., Asselbergs, F. W., Srikanth, V., Thomson, R., McWhirter, R., Moran, C., Callisaya, M., Phan, T., Rutten-Jacobs, L. C. A., Bevan, S., Tzourio, C., Mather, K. A., Sachdev, P. S., Van Duijn, C. M., Worrall, B. B., Dichgans, M., Kittner, S. J., Markus, H. S., Ikram, M. A., Fornage, M., Launer, L. J., Seshadri, S., Longstreth, W. T. & Debette, S., Jan 29 2019, In : Neurology. 92, 5, p. E486-E503

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

Genetic architecture of subcortical brain structures in 38,851 individuals

Satizabal, C. L., Adams, H. H. H., Hibar, D. P., White, C. C., Knol, M. J., Stein, J. L., Scholz, M., Sargurupremraj, M., Jahanshad, N., Roshchupkin, G. V., Smith, A. V., Bis, J. C., Jian, X., Luciano, M., Hofer, E., Teumer, A., van der Lee, S. J., Yang, J., Yanek, L. R., Lee, T. V. & 269 others, Li, S., Hu, Y., Koh, J. Y., Eicher, J. D., Desrivières, S., Arias-Vasquez, A., Chauhan, G., Athanasiu, L., Rentería, M. E., Kim, S., Hoehn, D., Armstrong, N. J., Chen, Q., Holmes, A. J., den Braber, A., Kloszewska, I., Andersson, M., Espeseth, T., Grimm, O., Abramovic, L., Alhusaini, S., Milaneschi, Y., Papmeyer, M., Axelsson, T., Ehrlich, S., Roiz-Santiañez, R., Kraemer, B., Håberg, A. K., Jones, H. J., Pike, G. B., Stein, D. J., Stevens, A., Bralten, J., Vernooij, M. W., Harris, T. B., Filippi, I., Witte, A. V., Guadalupe, T., Wittfeld, K., Mosley, T. H., Becker, J. T., Doan, N. T., Hagenaars, S. P., Saba, Y., Cuellar-Partida, G., Amin, N., Hilal, S., Nho, K., Mirza-Schreiber, N., Arfanakis, K., Becker, D. M., Ames, D., Goldman, A. L., Lee, P. H., Boomsma, D. I., Lovestone, S., Giddaluru, S., Le Hellard, S., Mattheisen, M., Bohlken, M. M., Kasperaviciute, D., Schmaal, L., Lawrie, S. M., Agartz, I., Walton, E., Tordesillas-Gutierrez, D., Davies, G. E., Shin, J., Ipser, J. C., Vinke, L. N., Hoogman, M., Jia, T., Burkhardt, R., Klein, M., Crivello, F., Janowitz, D., Carmichael, O. T., Haukvik, U. K., Aribisala, B. S., Schmidt, H., Strike, L. T., Cheng, C. Y., Risacher, S. L., Pütz, B., Fleischman, D. A., Assareh, A. A., Mattay, V. S., Buckner, R. L., Mecocci, P., Dale, A. M., Cichon, S., Boks, M. P., Matarin, M., Penninx, B. W. J. H., Calhoun, V. D., Chakravarty, M. M., Marquand, A. F., Macare, C., Kharabian Masouleh, S., Oosterlaan, J., Amouyel, P., Hegenscheid, K., Rotter, J. I., Schork, A. J., Liewald, D. C. M., de Zubicaray, G. I., Wong, T. Y., Shen, L., Sämann, P. G., Brodaty, H., Roffman, J. L., de Geus, E. J. C., Tsolaki, M., Erk, S., van Eijk, K. R., Cavalleri, G. L., van der Wee, N. J. A., McIntosh, A. M., Gollub, R. L., Bulayeva, K. B., Bernard, M., Richards, J. S., Himali, J. J., Loeffler, M., Rommelse, N., Hoffmann, W., Westlye, L. T., Valdés Hernández, M. C., Hansell, N. K., van Erp, T. G. M., Wolf, C., Kwok, J. B. J., Vellas, B., Heinz, A., Olde Loohuis, L. M., Delanty, N., Ho, B. C., Ching, C. R. K., Shumskaya, E., Singh, B., Hofman, A., van der Meer, D., Homuth, G., Psaty, B. M., Bastin, M. E., Montgomery, G. W., Foroud, T. M., Reppermund, S., Hottenga, J. J., Simmons, A., Meyer-Lindenberg, A., Cahn, W., Whelan, C. D., van Donkelaar, M. M. J., Yang, Q., Hosten, N., Green, R. C., Thalamuthu, A., Mohnke, S., Hulshoff Pol, H. E., Lin, H., Jack, C. R., Schofield, P. R., Mühleisen, T. W., Maillard, P., Potkin, S. G., Wen, W., Fletcher, E., Toga, A. W., Gruber, O., Huentelman, M., Davey Smith, G., Launer, L. J., Nyberg, L., Jönsson, E. G., Crespo-Facorro, B., Koen, N., Greve, D. N., Uitterlinden, A. G., Weinberger, D. R., Steen, V. M., Fedko, I. O., Groenewold, N. A., Niessen, W. J., Toro, R., Tzourio, C., Longstreth, W. T., Ikram, M. K., Smoller, J. W., van Tol, M. J., Sussmann, J. E., Paus, T., Lemaître, H., Schroeter, M. L., Mazoyer, B., Andreassen, O. A., Holsboer, F., Depondt, C., Veltman, D. J., Turner, J. A., Pausova, Z., Schumann, G., van Rooij, D., Djurovic, S., Deary, I. J., McMahon, K. L., Müller-Myhsok, B., Brouwer, R. M., Soininen, H., Pandolfo, M., Wassink, T. H., Cheung, J. W., Wolfers, T., Martinot, J. L., Zwiers, M. P., Nauck, M., Melle, I., Martin, N. G., Kanai, R., Westman, E., Kahn, R. S., Sisodiya, S. M., White, T., Saremi, A., van Bokhoven, H., Brunner, H. G., Völzke, H., Wright, M. J., van ‘t Ent, D., Nöthen, M. M., Ophoff, R. A., Buitelaar, J. K., Fernández, G., Sachdev, P. S., Rietschel, M., van Haren, N. E. M., Fisher, S. E., Beiser, A. S., Francks, C., Saykin, A. J., Mather, K. A., Romanczuk-Seiferth, N., Hartman, C. A., DeStefano, A. L., Heslenfeld, D. J., Weiner, M. W., Walter, H., Hoekstra, P. J., Nyquist, P. A., Franke, B., Bennett, D. A., Grabe, H. J., Johnson, A. D., Chen, C., van Duijn, C. M., Lopez, O. L., Fornage, M., Wardlaw, J. M., Schmidt, R., DeCarli, C., De Jager, P. L., Villringer, A., Debette, S., Gudnason, V., Medland, S. E., Shulman, J. M., Thompson, P. M., Seshadri, S. & Ikram, M. A., Nov 1 2019, In : Nature Genetics. 51, 11, p. 1624-1636 13 p.

Research output: Contribution to journalArticle

6 Scopus citations

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

Alzheimer Disease Genetics Consortium (ADGC), The European Alzheimer’s Disease Initiative (EADI), Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium (CHARGE), & Genetic and Environmental Risk in AD/Defining Genetic, Polygenic and Environmental Risk for Alzheimer’s Disease Consortium (GERAD/PERADES), Mar 1 2019, In : Nature Genetics. 51, 3, p. 414-430 17 p.

Research output: Contribution to journalArticle

154 Scopus citations

Genome-wide association analysis of hippocampal volume identifies enrichment of neurogenesis-related pathways

Alzheimer’S Disease Neuroimaging Initiative (Adni), Dec 1 2019, In : Scientific reports. 9, 1, 14498.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Global & Community Health: Brief in-hospital cognitive screening anticipates complex admissions and may detect dementia

Bissig, D. & DeCarli, C., Mar 26 2019, In : Neurology. 92, 13, p. 631-634 4 p.

Research output: Contribution to journalArticle

Open Access

Harmonizing brain magnetic resonance imaging methods for vascular contributions to neurodegeneration

Smith, E. E., Biessels, G. J., De Guio, F., de Leeuw, F. E., Duchesne, S., Düring, M., Frayne, R., Ikram, M. A., Jouvent, E., MacIntosh, B. J., Thrippleton, M. J., Vernooij, M. W., Adams, H., Backes, W. H., Ballerini, L., Black, S. E., Chen, C., Corriveau, R., DeCarli, C., Greenberg, S. M. & 29 others, Gurol, M. E., Ingrisch, M., Job, D., Lam, B. Y. K., Launer, L. J., Linn, J., McCreary, C. R., Mok, V. C. T., Pantoni, L., Pike, G. B., Ramirez, J., Reijmer, Y. D., Romero, J. R., Ropele, S., Rost, N. S., Sachdev, P. S., Scott, C. J. M., Seshadri, S., Sharma, M., Sourbron, S., Steketee, R. M. E., Swartz, R. H., van Oostenbrugge, R., van Osch, M., van Rooden, S., Viswanathan, A., Werring, D., Dichgans, M. & Wardlaw, J. M., Dec 1 2019, In : Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 11, p. 191-204 14 p.

Research output: Contribution to journalShort survey

Open Access
11 Scopus citations

Interpretable classification of Alzheimer’s disease pathologies with a convolutional neural network pipeline

Tang, Z., Chuang, K. V., DeCarli, C., Jin, L-W., Beckett, L. A., Keiser, M. J. & Dugger, B., Dec 1 2019, In : Nature communications. 10, 1, 2173.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations

Interrelations Between Arterial Stiffness, Target Organ Damage, and Cardiovascular Disease Outcomes

Vasan, R. S., Short, M. I., Niiranen, T. J., Xanthakis, V., DeCarli, C., Cheng, S., Seshadri, S. & Mitchell, G. F., Jan 1 2019, In : Journal of the American Heart Association. 8, 14, e012141.

Research output: Contribution to journalArticle

Open Access
10 Scopus citations

Measures of obesity are associated with MRI markers of brain aging: The Northern Manhattan Study

Caunca, M. R., Gardener, H., Simonetto, M., Cheung, Y. K., Alperin, N., Yoshita, M., DeCarli, C., Elkind, M. S. V., Sacco, R. L., Wright, C. B. & Rundek, T., Aug 20 2019, In : Neurology. 93, 8, p. e791-e803

Research output: Contribution to journalArticle

3 Scopus citations

Methionine Sulfoxide Reductase-B3 Risk Allele Implicated in Alzheimer's Disease Associates with Increased Odds for Brain Infarcts

Conner, S. C., Benayoun, L., Himali, J. J., Adams, S. L., Yang, Q., DeCarli, C., Blusztajn, J. K., Beiser, A., Seshadri, S. & Delalle, I., Jan 1 2019, In : Journal of Alzheimer's Disease. 68, 1, p. 357-365 9 p.

Research output: Contribution to journalArticle

1 Scopus citations

Multimodal Hippocampal Subfield Grading For Alzheimer’s Disease Classification

Alzheimer’s Disease Neuroimaging Initiative, Dec 1 2019, In : Scientific reports. 9, 1, 13845.

Research output: Contribution to journalArticle

Open Access
8 Scopus citations

Multisite study of the relationships between antemortem [ 11 C]PIB-PET Centiloid values and postmortem measures of Alzheimer's disease neuropathology

La Joie, R., Ayakta, N., Seeley, W. W., Borys, E., Boxer, A. L., DeCarli, C., Doré, V., Grinberg, L. T., Huang, E., Hwang, J. H., Ikonomovic, M. D., Jack, C., Jagust, W. J., Jin, L-W., Klunk, W. E., Kofler, J., Lesman-Segev, O. H., Lockhart, S. N., Lowe, V. J., Masters, C. L. & 15 others, Mathis, C. A., McLean, C. L., Miller, B. L., Mungas, D. M., O'Neil, J. P., Olichney, J. M., Parisi, J. E., Petersen, R. C., Rosen, H. J., Rowe, C. C., Spina, S., Vemuri, P., Villemagne, V. L., Murray, M. E. & Rabinovici, G. D., Feb 1 2019, In : Alzheimer's and Dementia. 15, 2, p. 205-216 12 p.

Research output: Contribution to journalArticle

15 Scopus citations
6 Scopus citations

Night-time systolic blood pressure and subclinical cerebrovascular disease: the Cardiovascular Abnormalities and Brain Lesions (CABL) study

Nakanishi, K., Jin, Z., Homma, S., Elkind, M. S. V., Rundek, T., Schwartz, J. E., Lee, T. C., Tugcu, A., Yoshita, M., DeCarli, C., Wright, C. B., Sacco, R. L. & Di Tullio, M. R., Jul 1 2019, In : European heart journal cardiovascular Imaging. 20, 7, p. 765-771 7 p.

Research output: Contribution to journalArticle

6 Scopus citations

Non-coding variability at the APOE locus contributes to the Alzheimer’s risk

Alzheimer’s Disease Neuroimaging Initiative, Dec 1 2019, In : Nature communications. 10, 1, 3310.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Plasma biomarkers of astrocytic and neuronal dysfunction in early- and late-onset Alzheimer's disease

Elahi, F. M., Casaletto, K. B., La Joie, R., Walters, S. M., Harvey, D., Wolf, A., Edwards, L., Rivera-Contreras, W., Karydas, A., Cobigo, Y., Rosen, H. J., DeCarli, C., Miller, B. L., Rabinovici, G. D. & Kramer, J. H., Jan 1 2019, (Accepted/In press) In : Alzheimer's and Dementia.

Research output: Contribution to journalArticle

2 Scopus citations

Plasma total-tau as a biomarker of stroke risk in the community

Pase, M. P., Himali, J. J., Aparicio, H. J., Romero, J. R., Satizabal, C. L., Maillard, P., DeCarli, C., Beiser, A. S. & Seshadri, S., Jan 1 2019, In : Annals of Neurology. 86, 3, p. 463-467 5 p.

Research output: Contribution to journalArticle

3 Scopus citations