Charles C Lee, PhD

Assistant Adjunct Professor

  • 1222 Citations
  • 21 h-Index
20012020
If you made any changes in Pure, your changes will be visible here soon.

Research Output 2001 2020

  • 1222 Citations
  • 21 h-Index
  • 40 Article
Filter
Article
2020

Dosing and Re-Administration of Lentiviral Vector for In Vivo Gene Therapy in Rhesus Monkeys and ADA-Deficient Mice

Carbonaro-Sarracino, D. A., Tarantal, A. F., Lee, C. C. I., Kaufman, M. L., Wandro, S., Jin, X., Martinez, M., Clark, D. N., Chun, K., Koziol, C., Hardee, C. L., Wang, X. & Kohn, D. B., Mar 13 2020, In : Molecular Therapy - Methods and Clinical Development. 16, p. 78-93 16 p.

Research output: Contribution to journalArticle

Open Access
Macaca mulatta
Genetic Therapy
Antibody Formation
Anti-Idiotypic Antibodies
Spleen
2019

Hyper-Crosslinked Carbohydrate Polymer for Repair of Critical-Sized Bone Defects

Koleva, P. M., Keefer, J. H., Ayala, A. M., Lorenzo, I., Han, C. E., Pham, K., Ralston, S. E., Kim, K. D. & Lee, C. C., Jul 1 2019, In : BioResearch Open Access. 8, 1, p. 111-120 10 p.

Research output: Contribution to journalArticle

Open Access
Polymers
Bone
Repair
Carbohydrates
Bone and Bones

Stem and progenitor cell microenvironment for bone regeneration and repair

Lee, C. C., Hirasawa, N., Garcia, K. G., Ramanathan, D. & Kim, K. D., Jan 1 2019, In : Regenerative Medicine. 14, 7, p. 693-702 10 p.

Research output: Contribution to journalArticle

Stem Cell Niche
Bone Regeneration
Stem cells
Mesenchymal Stromal Cells
Bone
2017
8 Citations (Scopus)

Systemic and persistent muscle gene expression in rhesus monkeys with a liver de-targeted adeno-associated virus vector

Tarantal, A. F., Lee, C. C., Martinez, M. L., Asokan, A. & Samulski, R. J., May 1 2017, In : Human Gene Therapy. 28, 5, p. 385-391 7 p.

Research output: Contribution to journalArticle

Dependovirus
Macaca mulatta
Firefly Luciferases
Gene Expression
Muscles
2016
5 Citations (Scopus)

Transfer of Therapeutic Genes into Fetal Rhesus Monkeys Using Recombinant Adeno-Associated Type i Viral Vectors

Conlon, T. J., Mah, C. S., Pacak, C. A., Rucker Henninger, M. B., Erger, K. E., Jorgensen, M. L., Lee, C. C., Tarantal, A. F. & Byrne, B. J., Dec 1 2016, In : Human Gene Therapy Clinical Development. 27, 4, p. 152-159 8 p.

Research output: Contribution to journalArticle

Macaca mulatta
Glycogen Storage Disease Type II
Diaphragm
Dependovirus
Dystrophin
2015
6 Citations (Scopus)

Development of operational immunologic tolerance with neonatal gene transfer in nonhuman primates: Preliminary studies

Tai, D. S., Hu, C., Lee, C. C., Martinez, M., Cantero, G., Kim, E. H., Tarantal, A. F. & Lipshutz, G. S., Nov 1 2015, In : Gene Therapy. 22, 11, p. 923-930 8 p.

Research output: Contribution to journalArticle

Ovalbumin
Primates
Dependovirus
Haplorhini
Genes
2014
2 Citations (Scopus)

Anti-non-Gal-specific combination treatment with an anti-idiotypic Ab and an inhibitory small molecule mitigates the xenoantibody response

Stewart, J. M., Tarantal, A. F., Chen, Y., Appleby, N. C., Fuentes, T. I., Lee, C. C., Salvaris, E. J., D'Apice, A. J. F., Cowan, P. J. & Kearns-Jonker, M., 2014, In : Xenotransplantation. 21, 3, p. 254-266 13 p.

Research output: Contribution to journalArticle

Heterophile Antibodies
Therapeutics
Anti-Idiotypic Antibodies
Swine
Immunoglobulin M
4 Citations (Scopus)

Effects of vector backbone and pseudotype on lentiviral vector-mediated gene transfer: Studies in infant ADA-Deficient mice and rhesus monkeys

Sarracino, D. C., Tarantal, A. F., Lee, C. C., Martinez, M., Jin, X., Wang, X., Hardee, C. L., Geiger, S., Kahl, C. A. & Kohn, D. B., Jan 1 2014, In : Molecular Therapy. 22, 10, p. 1803-1816 14 p.

Research output: Contribution to journalArticle

Vesicular Stomatitis
Adenosine Deaminase
Macaca mulatta
Severe Combined Immunodeficiency
Simian Immunodeficiency Virus
7 Citations (Scopus)

Myeloid-lymphoid ontogeny in the rhesus monkey (Macaca mulatta)

Batchelder, C. A., Duru, N., Lee, C. C., Baker, C. A. R., Swainson, L., Mccune, J. M. & Tarantal, A. F., 2014, In : Anatomical Record. 297, 8, p. 1392-1406 15 p.

Research output: Contribution to journalArticle

Macaca mulatta
ontogeny
Thymus Gland
spleen
Spleen
2013
6 Citations (Scopus)

Characterization of Growth, Glomerular Number, and Tubular Proteins in the Developing Rhesus Monkey Kidney

Batchelder, C. A., Keyser, J. L., Lee, C. C. & Tarantal, A. F., Nov 2013, In : Anatomical Record. 296, 11, p. 1747-1757 11 p.

Research output: Contribution to journalArticle

calbindin
Calbindins
Macaca mulatta
kidneys
Kidney
10 Citations (Scopus)
positron-emission tomography
radiolabeling
Positron emission tomography
blood cells
Macaca mulatta
93 Citations (Scopus)

Tissue Specificity of Decellularized Rhesus Monkey Kidney and Lung Scaffolds

Nakayama, K. H., Lee, C. C., Batchelder, C. A. & Tarantal, A. F., May 22 2013, In : PLoS One. 8, 5, e64134.

Research output: Contribution to journalArticle

Organ Specificity
Macaca mulatta
Scaffolds
lungs
kidneys
2012
13 Citations (Scopus)

Radiolabeling and in vivo imaging of transplanted renal lineages differentiated from human embryonic stem cells in fetal rhesus monkeys

Tarantal, A. F., Lee, C. C., Batchelder, C. A., Christensen, J. E., Prater, D. & Cherry, S. R., Apr 2012, In : Molecular Imaging and Biology. 14, 2, p. 197-204 8 p.

Research output: Contribution to journalArticle

Macaca mulatta
Positron-Emission Tomography
Kidney
Fluorescence In Situ Hybridization
Transplants
4 Citations (Scopus)

Stem cell microenvironment as a potential therapeutic target

Lee, C. C. & Kim, K. D., Jan 2012, In : Regenerative Medicine. 7, 1, p. 3-5 3 p.

Research output: Contribution to journalArticle

Stem Cell Niche
Organ Culture Techniques
Stem Cell Transplantation
Stem cells
Mesenchymal Stromal Cells
2011
37 Citations (Scopus)

Renal tissue engineering with decellularized rhesus monkey kidneys: Age-related differences

Nakayama, K. H., Batchelder, C. A., Lee, C. C. & Tarantal, A. F., Dec 1 2011, In : Tissue Engineering - Part A. 17, 23-24, p. 2891-2901 11 p.

Research output: Contribution to journalArticle

Tissue Engineering
Macaca mulatta
Tissue engineering
Scaffolds
Kidney
2010
48 Citations (Scopus)

Clonal analysis and hierarchy of human bone marrow mesenchymal stem and progenitor cells

Lee, C. C., Christensen, J. E., Yoder, M. C. & Tarantal, A. F., Jan 2010, In : Experimental Hematology. 38, 1, p. 46-54 9 p.

Research output: Contribution to journalArticle

Mesenchymal Stromal Cells
Bone Marrow
Peroxisome Proliferator-Activated Receptors
Bone Marrow Cells
Integrin-Binding Sialoprotein
221 Citations (Scopus)

Decellularized rhesus monkey kidney as a three-dimensional scaffold for renal tissue engineering

Nakayama, K. H., Batchelder, C. A., Lee, C. C. & Tarantal, A. F., Jul 1 2010, In : Tissue Engineering - Part A. 16, 7, p. 2207-2216 10 p.

Research output: Contribution to journalArticle

Tissue Engineering
Scaffolds (biology)
Macaca mulatta
Tissue engineering
Scaffolds
43 Citations (Scopus)
Dependovirus
Macaca mulatta
Luciferases
Firefly Luciferases
Transgenes
19 Citations (Scopus)

Ontogeny of the Kidney and Renal Developmental Markers in the Rhesus Monkey (Macaca Mulatta)

Batchelder, C. A., Lee, C. C., Martinez, M. L. & Tarantal, A. F., Nov 2010, In : Anatomical Record. 293, 11, p. 1971-1983 13 p.

Research output: Contribution to journalArticle

Nestin
Macaca mulatta
ontogeny
maturation
muscle
2009
12 Citations (Scopus)

Characterization and culture of fetal rhesus monkey renal cortical cells

Leapley, A. C., Lee, C. C., Batchelder, C. A., Yoder, M. C., Matsell, D. G. & Tarantal, A. F., 2009, In : Pediatric Research. 66, 4, p. 448-454 7 p.

Research output: Contribution to journalArticle

Podocytes
Macaca mulatta
Kidney
Extracellular Matrix
Nestin
38 Citations (Scopus)

Influence of the oxygen microenvironment on the proangiogenic potential of human endothelial colony forming cells

Decaris, M. L., Lee, C. C., Yoder, M. C., Tarantal, A. F. & Leach, J. K., Dec 2009, In : Angiogenesis. 12, 4, p. 303-311 9 p.

Research output: Contribution to journalArticle

Oxygen
Endothelial cells
Tissue
Air
Tissue regeneration
22 Citations (Scopus)
Macaca mulatta
Allografts
Fibroblasts
Cell Survival
Firefly Luciferases
61 Citations (Scopus)

Renal ontogeny in the rhesus monkey (Macaca mulatta) and directed differentiation of human embryonic stem cells towards kidney precursors

Batchelder, C. A., Lee, C. C., Matsell, D. G., Yoder, M. C. & Tarantal, A. F., Jul 2009, In : Differentiation. 78, 1, p. 45-56 12 p.

Research output: Contribution to journalArticle

Macaca mulatta
Kidney
Cell Differentiation
Bone Morphogenetic Protein 7
Vimentin
2008
22 Citations (Scopus)

Age-related gene expression profiles of rhesus monkey bone marrow-derived mesenchymal stem cells

Hacia, J. G., Lee, C. C., Jimenez, D. F., Karaman, M. W., Ho, V. V., Siegmund, K. D. & Tarantal, A. F., Mar 1 2008, In : Journal of Cellular Biochemistry. 103, 4, p. 1198-1210 13 p.

Research output: Contribution to journalArticle

Stem cells
Macaca mulatta
Mesenchymal Stromal Cells
Transcriptome
Gene expression
30 Citations (Scopus)

Growth, differentiation, and biochemical signatures of rhesus monkey mesenchymal stem cells

Kim, B. S., Lee, C. C., Christensen, J. E., Huser, T. R., Chan, J. W. & Tarantal, A. F., Feb 1 2008, In : Stem Cells and Development. 17, 1, p. 185-198 14 p.

Research output: Contribution to journalArticle

Macaca mulatta
Mesenchymal Stromal Cells
Growth
Age Groups
Raman Spectrum Analysis
39 Citations (Scopus)
Pyruvaldehyde
monkeys
stem cells
Hematopoietic Stem Cells
Stem cells
2007
14 Citations (Scopus)

Gene therapy to inhibit xenoantibody production using lentiviral vectors in non-human primates

Fischer-Lougheed, J. Y., Tarantal, A. F., Shulkin, I., Mitsuhashi, N., Kohn, D. B., Lee, C. C. & Kearns-Jonker, M., Jan 2007, In : Gene Therapy. 14, 1, p. 49-57 9 p.

Research output: Contribution to journalArticle

Heterophile Antibodies
Galactosyltransferases
Chimerism
Genetic Therapy
Primates
2006
53 Citations (Scopus)

Comparison of growth and differentiation of fetal and adult rhesus monkey mesenchymal stem cells

Lee, C. C., Ye, F. & Tarantal, A. F., Apr 2006, In : Stem Cells and Development. 15, 2, p. 209-220 12 p.

Research output: Contribution to journalArticle

Fetal Development
Macaca mulatta
Mesenchymal Stromal Cells
Simian foamy virus
Tenofovir
21 Citations (Scopus)

Effects of busulfan dose escalation on engraftment of infant rhesus monkey hematopoietic stem cells after gene marking by a lentiviral vector

Kahl, C. A., Tarantal, A. F., Lee, C. C., Jimenez, D. F., Choi, C., Pepper, K., Petersen, D., Fletcher, M. D., Leapley, A. C., Fisher, J., Burns, T. S., Ultsch, M. N., Dorey, F. J. & Kohn, D. B., Mar 2006, In : Experimental Hematology. 34, 3, p. 369-381 13 p.

Research output: Contribution to journalArticle

Busulfan
Hematopoietic Stem Cells
Macaca mulatta
Genes
Bone Marrow
39 Citations (Scopus)
Firefly Luciferases
Optical Imaging
Human Herpesvirus 1
Haplorhini
Gene Expression
2005
23 Citations (Scopus)
Cell Lineage
Hematopoietic Stem Cells
Macaca mulatta
Cell Cycle
Second Pregnancy Trimester
34 Citations (Scopus)

Fetal CD34+ cells in the maternal circulation and long-term microchimerism in rhesus monkeys (Macaca mulatta)

Jimenez, D. F., Leapley, A. C., Lee, C. C., Ultsch, M. N. & Tarantal, A. F., Jan 27 2005, In : Transplantation. 79, 2, p. 142-146 5 p.

Research output: Contribution to journalArticle

Chimerism
Macaca mulatta
Mothers
Pregnancy
Y Chromosome
37 Citations (Scopus)

Fetal gene transfer using lentiviral vectors and the potential for germ cell transduction in rhesus monkeys (Macaca mulatta)

Lee, C. C., Jimenez, D. F., Kohn, D. B. & Tarantal, A. F., Apr 2005, In : Human Gene Therapy. 16, 4, p. 417-425 9 p.

Research output: Contribution to journalArticle

Macaca mulatta
Germ Cells
Fetus
Vesicular Stomatitis
Genes
34 Citations (Scopus)

HIV-1-derived lentiviral vectors and fetal route of administration on transgene biodistribution and expression in rhesus monkeys

Jimenez, D. F., Lee, C. C., O'Shea, C. E., Kohn, D. B. & Tarantal, A. F., May 2005, In : Gene Therapy. 12, 10, p. 821-830 10 p.

Research output: Contribution to journalArticle

Macaca mulatta
Transgenes
HIV-1
Pregnancy
Genes
51 Citations (Scopus)

Intrapulmonary and intramyocardial gene transfer in rhesus monkeys (Macaca mulatta): Safety and efficiency of HIV-1-derived lentiviral vectors for fetal gene delivery

Tarantal, A. F., McDonald, R. J., Jimenez, D. F., Lee, C. C., O'Shea, C. E., Leapley, A. C., Won, R. H., Plopper, C., Lutzko, C. & Kohn, D. B., Jul 2005, In : Molecular Therapy. 12, 1, p. 87-98 12 p.

Research output: Contribution to journalArticle

Macaca mulatta
HIV-1
Safety
Lung
Genes
2004
41 Citations (Scopus)

Morphological analysis and lentiviral transduction of fetal monkey bone marrow-derived mesenchymal stem cells

Lee, C. C., Kohn, D. B., Ekert, J. E. & Tarantal, A. F., Jan 2004, In : Molecular Therapy. 9, 1, p. 112-123 12 p.

Research output: Contribution to journalArticle

Mesenchymal Stromal Cells
Haplorhini
Cell Cycle
Bone Marrow
Macaca mulatta
7 Citations (Scopus)

Simian Immunodeficiency Virus Infection of Hematopoietic Stem Cells and Bone Marrow Stromal Cells

Lee, C. C., Cowan, M. J., Kohn, D. B. & Tarantal, A. F., May 1 2004, In : Journal of Acquired Immune Deficiency Syndromes. 36, 1, p. 553-561 9 p.

Research output: Contribution to journalArticle

Simian Immunodeficiency Virus
Virus Diseases
Hematopoietic Stem Cells
Mesenchymal Stromal Cells
Stromal Cells
2001
20 Citations (Scopus)

IGF-II and IGF binding protein (IGFBP-1, IGFBP-3) gene expression in fetal rhesus monkey tissues during the second and third trimesters

Lee, C. C., Goldstein, O., Han, V. K. M. & Tarantal, A. F., 2001, In : Pediatric Research. 49, 3, p. 379-387 9 p.

Research output: Contribution to journalArticle

Insulin-Like Growth Factor Binding Protein 1
Insulin-Like Growth Factor Binding Proteins
Insulin-Like Growth Factor Binding Protein 3
Insulin-Like Growth Factor II
Third Pregnancy Trimester
47 Citations (Scopus)

Lentiviral vector gene transfer into fetal rhesus monkeys (Macaca mulatta): Lung-targeting approaches

Tarantal, A. F., Lee, C. C., Ekert, J. E., McDonald, R. J., Kohn, D. B., Plopper, C., Case, S. S. & Bunnell, B. A., 2001, In : Molecular Therapy. 4, 6, p. 614-621 8 p.

Research output: Contribution to journalArticle

Macaca mulatta
Lung
Haplorhini
Pregnancy
Genes
51 Citations (Scopus)

Rhesus monkey model for fetal gene transfer: Studies with retroviral-based vector systems

Tarantal, A. F., O'Rourke, J. P., Case, S. S., Newbound, G. C., Li, J., Lee, C. C., Baskin, C. R., Kohn, D. B. & Bunnell, B. A., 2001, In : Molecular Therapy. 3, 2, p. 128-138 11 p.

Research output: Contribution to journalArticle

Macaca mulatta
Murine Leukemia Viruses
Vesicular Stomatitis
Fetus
Genes