Alexey Tomilov, BS; MS; PhD

Associate Scientist

  • 796 Citations
  • 14 h-Index
19992020

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

  • 796 Citations
  • 14 h-Index
  • 47 Article
  • 1 Chapter
  • 1 Review article
Filter
Article
2020

Cetylpyridinium chloride is a potent AMP-activated kinase (AMPK) inducer and has therapeutic potential in cancer

Allen, S. A., Datta, S., Sandoval, J., Tomilov, A., Sears, T., Woolard, K., Angelastro, J. M. & Cortopassi, G. A., Jan 2020, In : Mitochondrion. 50, p. 19-24 6 p.

Research output: Contribution to journalArticle

1 Scopus citations
2018

A Ketogenic Diet Extends Longevity and Healthspan in Adult Mice

Roberts, M. N., Wallace, M. A., Tomilov, A. A., Zhou, Z., Marcotte, G. R., Tran, D., Perez, G., Gutierrez-Casado, E., Koike, S., Knotts, T. A., Imai, D. M., Griffey, S. M., Kim, K., Hagopian, K., McMackin, M. Z., Haj, F. G., Baar, K., Cortopassi, G. A., Ramsey, J. J. & Lopez-Dominguez, J. A., Jan 1 2018, (Accepted/In press) In : Cell Metabolism.

Research output: Contribution to journalArticle

7 Scopus citations

Idebenone is a cytoprotective insulin sensitizer whose mechanism is Shc inhibition

Tomilov, A., Allen, S., Hui, C. K., Bettaieb, A. & Cortopassi, G. A., Nov 1 2018, In : Pharmacological Research. 137, p. 89-103 15 p.

Research output: Contribution to journalArticle

2 Scopus citations

Small molecules bind human mTOR protein and inhibit mTORC1 specifically

Allen, S. A., Tomilov, A. & Cortopassi, G. A., Sep 1 2018, In : Biochemical Pharmacology. 155, p. 298-304 7 p.

Research output: Contribution to journalArticle

1 Scopus citations
2017

A Ketogenic Diet Extends Longevity and Healthspan in Adult Mice

Roberts, M. N., Wallace, M. A., Tomilov, A., Zhou, Z., Marcotte, G. R., Tran, D., Perez, G., Gutierrez-Casado, E., Koike, S., Knotts, T. A., Imai, D., Griffey, S. M., Kim, K., Hagopian, K., Haj, F., Baar, K., Cortopassi, G. A., Ramsey, J. J. & Lopez-Dominguez, J. A., Sep 5 2017, In : Cell Metabolism. 26, 3, p. 539-546.e5

Research output: Contribution to journalArticle

95 Scopus citations

In Vitro Evaluation of Mitochondrial Function and Estrogen Signaling in Cell Lines Exposed to the Antiseptic Cetylpyridinium Chloride

Datta, S., He, G., Tomilov, A., Sahdeo, S., Denison, M. S. & Cortopassi, G. A., Aug 22 2017, In : Environmental Health Perspectives. 125, 8, 1 p.

Research output: Contribution to journalArticle

10 Scopus citations

Synthesis and biochemical characterization of EGF receptor in a water-soluble membrane model system

Scharadin, T. M., He, W., Yiannakou, Y., Tomilov, A., Saldana, M., Cortopassi, G. A., Carraway, K. L., Coleman, M. A. & Henderson, P., Jun 1 2017, In : PLoS One. 12, 6, 0177761.

Research output: Contribution to journalArticle

2 Scopus citations
2016

Galectin-3 regulates inflammasome activation in cholestatic liver injury

Tian, J., Yang, G., Chen, H. Y., Hsu, D. K., Tomilov, A., Olson, K. A., Dehnad, A., Fish, S. R., Cortopassi, G. A., Zhao, B., Liu, F-T., Gershwin, M. E., Torok, N. J. & Jiang, X., Dec 1 2016, In : FASEB Journal. 30, 12, p. 4202-4213 12 p.

Research output: Contribution to journalArticle

14 Scopus citations
7 Scopus citations
1 Scopus citations

p46Shc inhibits thiolase and lipid oxidation in mitochondria

Tomilov, A., Tomilova, N., Shan, Y., Hagopian, K., Bettaieb, A., Kim, K., Pelicci, P. G., Haj, F., Ramsey, J. J. & Cortopassi, G. A., Jun 10 2016, In : Journal of Biological Chemistry. 291, 24, p. 12575-12585 11 p.

Research output: Contribution to journalArticle

6 Scopus citations
2015
8 Scopus citations
2014

High-throughput screening of FDA-approved drugs using oxygen biosensor plates reveals secondary mitofunctional effects

Sahdeo, S., Tomilov, A., Komachi, K., Iwahashi, C., Datta, S., Hughes, O., Hagerman, P. J. & Cortopassi, G. A., 2014, In : Mitochondrion. 17, p. 116-125 10 p.

Research output: Contribution to journalArticle

16 Scopus citations

Shc depletion stimulates brown fat activity in vivo and in vitro

Tomilov, A., Bettaieb, A., Kim, K., Sahdeo, S., Tomilova, N., Lam, A., Hagopian, K., Connell, M., Fong, J., Rowland, D., Griffey, S. M., Ramsey, J. J., Haj, F. & Cortopassi, G. A., Dec 1 2014, In : Aging Cell. 13, 6, p. 1049-1058 10 p.

Research output: Contribution to journalArticle

10 Scopus citations
2012

Hepatic Src homology phosphatase 2 regulates energy balance in mice

Nagata, N., Matsuo, K., Bettaieb, A., Bakke, J., Matsuo, I., Graham, J., Xi, Y., Liu, S., Tomilov, A., Tomilova, N., Gray, S., Jung, D. Y., Ramsey, J. J., Kim, J. K., Cortopassi, G. A., Havel, P. J. & Haj, F., Jul 2012, In : Endocrinology. 153, 7, p. 3158-3169 12 p.

Research output: Contribution to journalArticle

30 Scopus citations

OPA1 mutation and late-onset cardiomyopathy: mitochondrial dysfunction and mtDNA instability.

Chen, L., Liu, T., Tran, A., Lu, X., Tomilov, A. A., Davies, V., Cortopassi, G., Chiamvimonvat, N., Bers, D. M., Votruba, M. & Knowlton, A. A., Oct 2012, In : Journal of the American Heart Association. 1, 5

Research output: Contribution to journalArticle

97 Scopus citations

Shc proteins influence the activities of enzymes involved in fatty acid oxidation and ketogenesis

Hagopian, K., Tomilov, A., Tomilova, N., Kim, K., Taylor, S. L., Lam, A. K., Cortopassi, G. A., McDonald, R. B. & Ramsey, J. J., Dec 2012, In : Metabolism: Clinical and Experimental. 61, 12, p. 1703-1713 11 p.

Research output: Contribution to journalArticle

8 Scopus citations

The TvPirin Gene Is necessary for haustorium development in the parasitic plant Triphysaria versicolor

Bandaranayake, P. C. G., Tomilov, A., Tomilova, N. B., Ngo, Q. A., Wickett, N., dePamphilis Claude W., C. W. & Yoder, J. I., Feb 1 2012, In : Plant Physiology. 158, 2, p. 1046-1053 8 p.

Research output: Contribution to journalArticle

17 Scopus citations
2011

The Shc locus regulates insulin signaling and adiposity in mammals

Tomilov, A., Ramsey, J. J., Hagopian, K., Giorgio, M., Kim, K., Lam, A., Migliaccio, E., Lloyd, K. C. K., Berniakovich, I., Prolla, T. A., Pelicci, P. & Cortopassi, G. A., Feb 2011, In : Aging Cell. 10, 1, p. 55-65 11 p.

Research output: Contribution to journalArticle

41 Scopus citations
2010

A single-electron reducing quinone oxidoreductase is necessary to induce haustorium development in the root parasitic plant Triphysaria

Bandaranayake, P. C. G., Filappova, T., Tomilov, A., Tomilova, N. B., Jamison-Mcclung, D., Ngo, Q., Inoue, K. & Yoder, J. I., Apr 1 2010, In : Plant Cell. 22, 4, p. 1404-1419 16 p.

Research output: Contribution to journalArticle

51 Scopus citations

Decreased superoxide production in macrophages of long-lived p66Shc knock-out mice

Tomilov, A., Bicocca, V., Schoenfeld, R. A., Giorgio, M., Migliaccio, E., Ramsey, J. J., Hagopian, K., Pelicci, P. G. & Cortopassi, G. A., 2010, In : Journal of Biological Chemistry. 285, 2, p. 1153-1165 13 p.

Research output: Contribution to journalArticle

44 Scopus citations
2008

Trans-specific gene silencing between host and parasitic plants

Tomilov, A., Tomilova, N. B., Wroblewski, T., Michelmore, R. W. & Yoder, J. I., Nov 2008, In : Plant Journal. 56, 3, p. 389-397 9 p.

Research output: Contribution to journalArticle

111 Scopus citations
2007

Agrobacterium tumefaciens and Agrobacterium rhizogenes transformed roots of the parasitic plant Triphysaria versicolor retain parasitic competence

Tomilov, A., Tomilova, N. & Yoder, J. I., Apr 1 2007, In : Planta. 225, 5, p. 1059-1071 13 p.

Research output: Contribution to journalArticle

40 Scopus citations
2005

Identification of the gene whose mutation leads to hypocoptyl tropism in Arabidopsis thaliana

Ogarkova, O. A., Tomilov, A., Tomilova, N. B. & Tarasov, V. A., Mar 1 2005, In : Russian Journal of Genetics. 41, 3, p. 337-338 2 p.

Research output: Contribution to journalArticle

Identification of the gene whose mutation leads to hypocotyl tropism in Arabidopsis thaliana

Ogarkova, O. A., Tomilov, A., Tomilova, N. B. & Tarasov, V. A., Dec 1 2005, In : Genetika. 41, 3, p. 427-429 3 p.

Research output: Contribution to journalArticle

Identification of the gene whose mutation leads to the appearance of recessive lethal germlings in Arabidopsis thaliana

Ogarkova, O. A., Tomilov, A., Tomilova, N. B. & Tarasov, V. A., Dec 1 2005, In : Ontogenez. 36, 3, p. 222-224 3 p.

Research output: Contribution to journalArticle

Identification of the gene whose mutation leads to the appearance of recessive lethal germlings in Arabidopsis thaliana

Ogarkova, O. A., Tomilov, A., Tomilova, N. B. & Tarasov, V. A., May 1 2005, In : Russian Journal of Developmental Biology. 36, 3, p. 181-183 3 p.

Research output: Contribution to journalArticle

Identification of the gene whose mutation leads to the morphological changes in the hypocotyl of Arabidopsis thaliana

Ogarkova, O. A., Tomilov, A., Tomilova, N. B., Pogorelko, G. V. & Tarasov, V. A., Dec 1 2005, In : Genetika. 41, 2, p. 166-170 5 p.

Research output: Contribution to journalArticle

Identification of the gene whose mutation leads to the morphological changes in the hypocotyl of Arabidopsis thaliana

Ogarkova, O. A., Tomilov, A., Tomilova, N. B., Pogorelko, G. V. & Tarasov, V. A., Feb 1 2005, In : Russian Journal of Genetics. 41, 2, p. 112-115 4 p.

Research output: Contribution to journalArticle

Localized hormone fluxes and early haustorium development in the hemiparasitic plant Triphysaria versicolor

Tomilov, A., Tomilova, N. B., Abdallah, I. & Yoder, J. I., Dec 1 2005, In : Plant Physiology. 138, 3, p. 1469-1480 12 p.

Research output: Contribution to journalArticle

43 Scopus citations

Pscroph, a parasitic plant EST database enriched for parasite associated transcripts

Torres, M. J., Tomilov, A., Tomilova, N., Reagan, R. L. & Yoder, J. I., Nov 16 2005, In : BMC Plant Biology. 5, 24.

Research output: Contribution to journalArticle

33 Scopus citations
2004

Identification of a putative regulatory gene of cotyledon development in Arabidopsis thaliana germinating seeds

Fursova, O. V., Pogorelko, G. V., Avsyuk, A. Y., Tomilova, N. V., Tomilov, A., Tarasov, V. A. & Ogarkova, O. A., Oct 27 2004, In : Doklady Akademii Nauk. 395, 5, p. 715-717 3 p.

Research output: Contribution to journalArticle

Identification of the potential gene that controlling cotyledon development in Arabidopsis thaliana seedlings.

Fursova, O. V., Pogorelko, G. V., Avsyuk, A. Y., Tomilova, N. V., Tomilov, A., Tarasov, V. A. & Ogarkova, O. A., Jan 1 2004, In : Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections / translated from Russian. 395, p. 161-162 2 p.

Research output: Contribution to journalArticle

1 Scopus citations

In vitro haustorium development in roots and root cultures of the hemiparasitic plant Triphysaria versicolor

Tomilov, A., Tomilova, N. & Yoder, J. I., Jun 1 2004, In : Plant Cell, Tissue and Organ Culture. 77, 3, p. 257-265 9 p.

Research output: Contribution to journalArticle

14 Scopus citations

Spasenie insertsionnykh retsessivnykh letal'nykh mutantov Arabidopsis thaliana.

Translated title of the contribution: Saving insertional recessive lethal mutants of Arabidopsis thalianaOgarkova, O. A., Tomilov, A., Tomilova, N. B. & Tarasov, V. A., May 1 2004, In : Ontogenez. 35, 3, p. 220-228 9 p.

Research output: Contribution to journalArticle

1 Scopus citations
2002

Two types of rDNA internal transcribed (ITS) in Capsicum genome

Ryzhova, N. N., Goryunova, S. V., Tomilov, A. & Kochieva, E. Z., Jan 1 2002, In : Doklady Akademii Nauk. 387, 2, p. 282-286 5 p.

Research output: Contribution to journalArticle

1 Scopus citations
1 Scopus citations
2001

Collection of arabidopsis thaliana morphological insertion mutants

Ogarkova, O. A., Tomilova, N. B., Tomilov, A. & Tarasov, V. A., Dec 1 2001, In : Genetika. 37, 8, p. 1081-1087 7 p.

Research output: Contribution to journalArticle

7 Scopus citations

Collection of Arabidopsis thaliana Morphological Insertion Mutants

Ogarkova, O. A., Tomilova, N. B., Tomilov, A. & Tarasov, V. A., Aug 1 2001, In : Russian Journal of Genetics. 37, 8, p. 899-904 6 p.

Research output: Contribution to journalArticle

5 Scopus citations

Hormone-Dependent insertional mutants of arabidopsis ihaliana with reduced viability and fertility

Tomilova, N. B., Tomilov, A., Ogarkova, O. A., Soldatova, O. & Tarasov, V. A., Dec 1 2001, In : Genetika. 37, 9, p. 1251-1257 7 p.

Research output: Contribution to journalArticle

Hormone-Dependent Insertional Mutants of Arabodopsis thaliana with Reduced Viability and Fertility

Tomilova, N. B., Tomilov, A., Ogarkova, O. A., Soldatova, O. P. & Tarasov, A. V., Sep 1 2001, In : Russian Journal of Genetics. 37, 9, p. 1048-1053 6 p.

Research output: Contribution to journalArticle

6 Scopus citations

Identification of a gene involved in the control of the root system development in Arabidopsis thaliana

Tomilov, A., Tomilova, N. B., Ogarkova, O. A. & Tarasov, V. A., Dec 1 2001, In : Genetika. 37, 1, p. 36-45 10 p.

Research output: Contribution to journalArticle

6 Scopus citations

Identification of a Gene Involved in the Control of the Root System Development in Arabidopsis thaliana

Tomilov, A., Tomilova, N. B., Ogarkova, O. A. & Tarasov, V. A., Jan 1 2001, In : Russian Journal of Genetics. 37, 1, p. 30-38 9 p.

Research output: Contribution to journalArticle

Identification of a mutant gene controlling necrotic cotyledons in developing seedlings of arabidopsis thaliana

Tomilova, N. B., Tomilov, A., Ogarkova, O. A. & Tarasov, V. A., Dec 1 2001, In : Genetika. 37, 4, p. 494-503 10 p.

Research output: Contribution to journalArticle

4 Scopus citations

Identification of a Mutant Gene Controlling Necrotic Cotyledons in Developing Seedlings of Arabidopsis thaliana

Tomilova, N. B., Tomilov, A., Ogarkova, O. A. & Tarasov, V. A., Apr 1 2001, In : Russian Journal of Genetics. 37, 4, p. 392-400 9 p.

Research output: Contribution to journalArticle

1 Scopus citations
1999

Insertional mutagenesis in arabidopsis thaliana: presonication of germinating seeds increases the efficiency of their transformation

Tomilov, A., Tomilova, N. B., Ogarkova, O. A. & Tarasov, V. A., Dec 1 1999, In : Genetika. 35, 9, p. 1214-1222 9 p.

Research output: Contribution to journalArticle

11 Scopus citations

Insertional Mutagenesis in Arabidopsis thaliana: Presonication of Germinating Seeds Increases the Efficiency of Their Transformation

Tomilov, A., Tomilova, N. B., Ogarkova, O. A. & Tarasov, V. A., Dec 1 1999, In : Russian Journal of Genetics. 35, 9, p. 1043-1049 7 p.

Research output: Contribution to journalArticle

4 Scopus citations