• 2995 Citations
  • 30 h-Index
19972020
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  • 1 Similar Profiles
Cytochrome P-450 CYP2D6 Medicine & Life Sciences
MicroRNAs Medicine & Life Sciences
Methoxydimethyltryptamines Medicine & Life Sciences
Harmaline Medicine & Life Sciences
Pharmaceutical Preparations Medicine & Life Sciences
Metabolism Chemical Compounds
Pharmacokinetics Medicine & Life Sciences
Cytochrome P-450 CYP3A Medicine & Life Sciences

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Projects 2007 2020

Recombinant microRNAs in xenobiotic disposition

Yu, A.

National Institutes of Health

3/1/162/29/20

Project: Research projectResearch Project

Xenobiotics
MicroRNAs
Untranslated RNA
Gene Expression
Pharmaceutical Preparations

MicroRNA-1291 in Regulation of Xenobiotic Disposition and Cell Differentiation

Yu, A.

National Institutes of Health

5/12/143/31/19

Project: Research projectResearch Project--Cooperative Agreements

Xenobiotics
MicroRNAs
Cell Differentiation
Drug and Narcotic Control
Neoplasms

A New MicroRNA-1291 Replacement Therapy for Pancreatic Cancer Disease

Yu, A. & Bader, A.

National Institutes of Health

9/15/148/31/16

Project: Research projectSmall Business Technology Transfer (STTR) Grants - Phase I

Pancreatic Diseases
MicroRNAs
Pancreatic Neoplasms
Neoplasms
Therapeutics
Cytochrome P-450 CYP2D6
Pharmacogenetics
Drug Interactions
Pharmaceutical Preparations
Pharmacokinetics

Research Output 1997 2019

Bioengineered miRNA-1291 prodrug therapy in pancreatic cancer cells and patient-derived xenograft mouse models

Tu, M. J., Ho, P. Y., Zhang, Q. Y., Jian, C., Qiu, J. X., Kim, E., Bold, R. J., Gonzalez, F. J., Bi, H. & Yu, A., Feb 1 2019, In : Cancer Letters. 442, p. 82-90 9 p.

Research output: Contribution to journalArticle

Prodrugs
MicroRNAs
Pancreatic Neoplasms
Heterografts
gemcitabine
1 Citations

Bioengineered noncoding RNAs selectively change cellular miRNome profiles for cancer therapy

Ho, P. Y., Duan, Z., Batra, N., Jilek, J. L., Tu, M. J., Qiu, J. X., Hu, Z., Wun, T., Lara, P. N., deVere White, R. W., Chen, H. & Yu, A., Jun 1 2018, In : Journal of Pharmacology and Experimental Therapeutics. 365, 3, p. 494-506 13 p.

Research output: Contribution to journalArticle

Untranslated RNA
MicroRNAs
Neoplasms
Bioengineering
Lung
2 Citations

Bioengineered NRF2-siRNA is effective to interfere with NRF2 pathways and improve chemosensitivity of human cancer cells

Li, P. C., Tu, M. J., Ho, P. Y., Jilek, J. L., Duan, Z., Zhang, Q. Y., Yu, A. X. & Yu, A., Jan 1 2018, In : Drug Metabolism and Disposition. 46, 1, p. 2-10 9 p.

Research output: Contribution to journalArticle

Small Interfering RNA
Osteosarcoma
Neoplasms
Antiporters
Bioengineering
2 Citations

Carnitine palmitoyltransferase 1C regulates cancer cell senescence through mitochondria-associated metabolic reprograming

Wang, Y., Chen, Y., Guan, L., Zhang, H., Huang, Y., Johnson, C. H., Wu, Z., Gonzalez, F. J., Yu, A., Huang, P., Wang, Y., Yang, S., Chen, P., Fan, X., Huang, M. & Bi, H., Jan 9 2018, (Accepted/In press) In : Cell Death and Differentiation. p. 1-14 14 p.

Research output: Contribution to journalArticle

Carnitine O-Palmitoyltransferase
Cell Aging
Mitochondria
Neoplasms
Physiological Stress

Effects of carnitine palmitoyltransferases on cancer cellular senescence

Guan, L., Chen, Y., Wang, Y., Zhang, H., Fan, S., Gao, Y., Jiao, T., Fu, K., Sun, J., Yu, A., Huang, M. & Bi, H., Jan 1 2018, (Accepted/In press) In : Journal of Cellular Physiology.

Research output: Contribution to journalArticle

Carnitine O-Palmitoyltransferase
Cell Aging
Protein Isoforms
Cell proliferation
Tumors