Pediatric Hematology and Oncology

Research Output

2018

A novel approach to immune tolerance induction in haemophilia A with factor VIII inhibitor

Thornburg, C. D. & Ducore, J. M., Jan 1 2018, (Accepted/In press) In : Haemophilia.

Research output: Contribution to journalArticle

Immunogenicity, efficacy and safety of Nuwiq® (human-cl rhFVIII) in previously untreated patients with severe haemophilia A—Interim results from the NuProtect Study

Liesner, R. J., Abashidze, M., Aleinikova, O., Altisent, C., Belletrutti, M. J., Borel-Derlon, A., Carcao, M., Chambost, H., Chan, A. K. C., Dubey, L., Ducore, J. M., Fouzia, N. A., Gattens, M., Gruel, Y., Guillet, B., Kavardakova, N., El Khorassani, M., Klukowska, A., Lambert, T., Lohade, S. & 10 others, Sigaud, M., Turea, V., Wu, J. K. M., Vdovin, V., Pavlova, A., Jansen, M., Belyanskaya, L., Walter, O., Knaub, S. & Neufeld, E. J., Mar 1 2018, In : Haemophilia. 24, 2, p. 211-220 10 p.

Research output: Contribution to journalArticle

15 Scopus citations

Measuring the Effects of an Animal-Assisted Intervention for Pediatric Oncology Patients and Their Parents: A Multisite Randomized Controlled Trial

McCullough, A., Ruehrdanz, A., Jenkins, M. A., Gilmer, M. J., Olson, J., Pawar, A. S., Holley, L., Sierra-Rivera, S., Linder, D. E., Pichette, D., Grossman, N. J., Hellman, C., Guérin, N. A. & O’Haire, M. E., May 1 2018, In : Journal of Pediatric Oncology Nursing. 35, 3, p. 159-177 19 p.

Research output: Contribution to journalArticle

10 Scopus citations

Physiological and behavioral effects of animal-assisted interventions on therapy dogs in pediatric oncology settings

McCullough, A., Jenkins, M. A., Ruehrdanz, A., Gilmer, M. J., Olson, J., Pawar, A. S., Holley, L., Sierra-Rivera, S., Linder, D. E., Pichette, D., Grossman, N. J., Hellman, C., Guérin, N. A. & O'Haire, M. E., Mar 1 2018, In : Applied Animal Behaviour Science. 200, p. 86-95 10 p.

Research output: Contribution to journalArticle

18 Scopus citations

The identification of at-risk patients and prevention of venous thromboembolism in pediatric cancer: guidance from the SSC of the ISTH

Tullius, B. P., Athale, U., van Ommen, C. H., Chan, A. K. C., Palumbo, J. S., Balagtas, J. M. S. & the Subcommittee on Hemostasis and Malignancy and the Subcommittee on Pediatric/Neonatal Thrombosis and Hemostasis, Jan 1 2018, In : Journal of Thrombosis and Haemostasis. 16, 1, p. 175-180 6 p.

Research output: Contribution to journalArticle

5 Scopus citations
2017

Hemophilia B gene therapy with a high-specific-activity factor IX variant

George, L. A., Sullivan, S. K., Giermasz, A., Rasko, J. E. J., Samelson-Jones, B. J., Ducore, J. M., Cuker, A., Sullivan, L. M., Majumdar, S., Teitel, J., McGuinn, C. E., Ragni, M. V., Luk, A. Y., Hui, D., Wright, J. F., Chen, Y., Liu, Y., Wachtel, K., Winters, A., Tiefenbacher, S. & 8 others, Arruda, V. R., Van Der Loo, J. C. M., Zelenaia, O., Takefman, D., Carr, M. E., Couto, L. B., Anguela, X. M. & High, K. A., Dec 7 2017, In : New England Journal of Medicine. 377, 23, p. 2215-2227 13 p.

Research output: Contribution to journalArticle

216 Scopus citations

PERSEPT 1: A phase 3 trial of activated eptacog beta for on-demand treatment of haemophilia inhibitor-related bleeding

Wang, M., Lawrence, J. B., Quon, D. V., Ducore, J. M., Simpson, M. L., Boggio, L. N., Mitchell, I. S., Yuan, G., Alexander, W. A. & Schved, J. F., 2017, (Accepted/In press) In : Haemophilia.

Research output: Contribution to journalArticle

7 Scopus citations

Primary Renal Lymphoma Presenting as End-Stage Renal Disease

Butani, L. & Ducore, J. M., 2017, In : Case Reports in Medicine. 2017, 9210648.

Research output: Contribution to journalArticle

2 Scopus citations
2016
2 Scopus citations

Prospective, multicenter study of postoperative deep-vein thrombosis in patients with haemophilia undergoing major orthopaedic surgery

Buckner, T. W., Leavitt, A. D., Ragni, M., Kempton, C. L., Elaine Eyster, M., Cuker, A., Lentz, S. R., Ducore, J. M., Leissinger, C., Wang, M. & Key, N. S., Jul 1 2016, In : Thrombosis and Haemostasis. 116, 1, p. 42-49 8 p.

Research output: Contribution to journalArticle

7 Scopus citations
2015

Dust metal loadings and the risk of childhood acute lymphoblastic leukemia

Whitehead, T. P., Ward, M. H., Colt, J. S., Dahl, G., Ducore, J. M., Reinier, K., Gunier, R. B., Katharine Hammond, S., Rappaport, S. M. & Metayer, C., Nov 1 2015, In : Journal of Exposure Science and Environmental Epidemiology. 25, 6, p. 593-598 6 p.

Research output: Contribution to journalArticle

2 Scopus citations

Loss of MXD3 induces apoptosis of Reh human precursor B acute lymphoblastic leukemia cells

Barisone, G., Satake, N., Lewis, C., Duong, C., Chen, C., Lam, K., Nolta, J. & Diaz, E. D., Apr 1 2015, In : Blood Cells, Molecules, and Diseases. 54, 4, p. 329-335 7 p.

Research output: Contribution to journalArticle

7 Scopus citations

Subcutaneous panniculitis-like T-cell lymphoma: Pediatric case series demonstrating heterogeneous presentation and option for watchful waiting

Johnston, E. E., Leblanc, R. E., Kim, J., Chung, J. H., Balagtas, J., Kim, Y. H. & Link, M. P., Nov 1 2015, In : Pediatric Blood and Cancer. 62, 11, p. 2025-2028 4 p.

Research output: Contribution to journalArticle

9 Scopus citations
2014
14 Scopus citations

A novel variant mutation for congenital dyserythropoietic anemia, type II

Song, J. Y., Pawar, A. S. & Collins, C., Dec 1 2014, In : Blood Cells, Molecules, and Diseases. 53, 4, p. 272-273 2 p.

Research output: Contribution to journalArticle

3 Scopus citations

Children and adolescents with ALL are taller than expected at diagnosis

Huang, T. & Ducore, J. M., Jan 2014, In : Journal of Pediatric Hematology/Oncology. 36, 1, p. 16-21 6 p.

Research output: Contribution to journalArticle

2 Scopus citations

Quartet partitioning reveals hybrid origins of the vertebrate

Syvanen, M., Ericksen, B., Linz, S. & Ducore, J. M., Jan 1 2014, Evolutionary Biology: Genome Evolution, Speciation, Coevolution and Origin of Life. Springer International Publishing, p. 191-205 15 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Targeted therapy with MXD3 siRNA, anti-CD22 antibody and nanoparticles for precursor B-cell acute lymphoblastic leukaemia

Satake, N., Duong, C., Chen, C., Barisone, G., Diaz, E. D., Tuscano, J., Rocke, D. M., Nolta, J. & Nitin, N., Nov 1 2014, In : British Journal of Haematology. 167, 4, p. 487-499 13 p.

Research output: Contribution to journalArticle

10 Scopus citations

WARM N COLD: Malignant and benign renal tumors in children

Sanchez, T. R., Ducore, J. M., Balagtas, J., Molloy, C. & Wootton-Gorges, S. L., 2014, In : Emergency Radiology. 21, 3, p. 261-269 9 p.

Research output: Contribution to journalArticle

3 Scopus citations

Whole-exome sequencing identifies a novel somatic mutation in MMP8 associated with a t(1;22)-acute megakaryoblastic leukemia

Kim, Y., Schulz, V. P., Satake, N., Gruber, T. A., Teixeira, A. M., Halene, S., Gallagher, P. G. & Krause, D. S., 2014, In : Leukemia. 28, 4, p. 945-948 4 p.

Research output: Contribution to journalArticle

5 Scopus citations
2013

Coagulation profile of liquid-state plasma

Gosselin, R. C., Marshall, C. S., Dwyre, D. M., Gresens, C., Davis, D., Scherer, L. & Taylor, D., Mar 2013, In : Transfusion. 53, 3, p. 579-590 12 p.

Research output: Contribution to journalArticle

14 Scopus citations

Efficacy of a CD22-targeted antibody-saporin conjugate in a xenograft model of precursor-B cell acute lymphoblastic leukemia

Kato, J., Satake, N., O'Donnell, R. T., Abuhay, M., Lewis, C. & Tuscano, J., Jan 2013, In : Leukemia Research. 37, 1, p. 83-88 6 p.

Research output: Contribution to journalArticle

14 Scopus citations
22 Scopus citations

Oral or parenteral administration of curcumin does not prevent the growth of high-risk t(4;11) acute lymphoblastic leukemia cells engrafted into a NOD/SCID mouse model

Zunino, S. J., Storms, D. H., Newman, J. W., Pedersen, T. L., Keen, C. L. & Ducore, J. M., Feb 2013, In : International Journal of Oncology. 42, 2, p. 741-748 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

Tobacco smoke exposure and the risk of childhood acute lymphoblastic and myeloid leukemias by cytogenetic subtype

Metayer, C., Zhang, L., Wiemels, J. L., Bartley, K., Schiffman, J., Ma, X., Aldrich, M. C., Chang, J. S., Selvin, S., Fu, C. H., Ducore, J. M., Smith, M. T. & Buffler, P. A., Sep 2013, In : Cancer Epidemiology Biomarkers and Prevention. 22, 9, p. 1600-1611 12 p.

Research output: Contribution to journalArticle

45 Scopus citations
2012

Anti-tumor activity of the HSP90 inhibitor SNX-2112 in pediatric cancer cell lines

Chinn, D. C., Holland, W. S., Yoon, J. M., Zwerdling, T. & Mack, P., Jun 2012, In : Pediatric Blood and Cancer. 58, 6, p. 885-890 6 p.

Research output: Contribution to journalArticle

13 Scopus citations

Dietary resveratrol does not delay engraftment, sensitize to vincristine or inhibit growth of high-risk acute lymphoblastic leukemia cells in NOD/SCID mice

Zunino, S. J., Storms, D. H., Newman, J. W., Pedersen, T. L., Keen, C. L. & Ducore, J. M., Dec 2012, In : International Journal of Oncology. 41, 6, p. 2207-2212 6 p.

Research output: Contribution to journalArticle

10 Scopus citations

Exchange transfusion therapy and its effects on real-time microcirculation in pediatric sickle cell anemia patients: An intravital microscopy study

Cheung, A. T. W., Miller, J. W., Miguelino, M. G., To, W. J., Li, J., Lin, X., Chen, P. C., Samarron, S. L., Wun, T., Zwerdling, T. & Green, R., Apr 2012, In : Journal of Pediatric Hematology/Oncology. 34, 3, p. 169-174 6 p.

Research output: Contribution to journalArticle

11 Scopus citations

Molecular targeting in childhood malignancies using nanoparticles

Satake, N., Barisone, G., Diaz, E. D., Nitin, N., Nolta, J. & Lam, K., 2012, Proceedings of SPIE - The International Society for Optical Engineering. Vol. 8373. 83730N

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Resveratrol given intraperitoneally does not inhibit the growth of high-risk t(4;11) acute lymphoblastic leukemia cells in a NOD/SCID mouse model

Zunino, S. J., Storms, D. H., Newman, J. W., Pedersen, T. L., Keen, C. L. & Ducore, J. M., Apr 2012, In : International Journal of Oncology. 40, 4, p. 1277-1284 8 p.

Research output: Contribution to journalArticle

13 Scopus citations
2011

Meningiomas in children and adolescents: A meta-analysis of individual patient data

Kotecha, R. S., Pascoe, E. M., Rushing, E. J., Rorke-Adams, L. B., Zwerdling, T., Gao, X., Li, X., Greene, S., Amirjamshidi, A., Kim, S. K., Lima, M. A., Hung, P. C., Lakhdar, F., Mehta, N., Liu, Y., Devi, B. I., Sudhir, B. J., Lund-Johansen, M., Gjerris, F., Cole, C. H. & 1 others, Gottardo, N. G., Dec 2011, In : The Lancet Oncology. 12, 13, p. 1229-1239 11 p.

Research output: Contribution to journalArticle

83 Scopus citations

Monosomy 21q22.11-q22.13 presenting as a Fanconi anemia phenotype

Byrd, R. S., Zwerdling, T., Moghaddam, B., Pinter, J. D. & Steinfeld, M. B., Jan 2011, In : American Journal of Medical Genetics, Part A. 155, 1, p. 120-125 6 p.

Research output: Contribution to journalArticle

13 Scopus citations

Nanoparticle targeted therapy against childhood acute lymphoblastic leukemia

Satake, N., Lee, J. S., Xiao, K., Luo, J., Sarangi, S., Chang, A., McLaughlin, B., Zhou, P., Kenney, E., Kraynov, L., Arnott, S., McGee, J., Nolta, J. & Lam, K., 2011, Proceedings of SPIE - The International Society for Optical Engineering. Vol. 8031. 80311U

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Power dependent oxygenation state transition of red blood cells in a single beam optical trap

Liu, R., Zheng, L., Matthews, D. L., Satake, N. & Chan, J. W., Jul 25 2011, In : Applied Physics Letters. 99, 4, 043702.

Research output: Contribution to journalArticle

22 Scopus citations

Raman spectroscopy of individual monocytes reveals that single-beam optical trapping of mononuclear cells occurs by their nucleus

Fore, S., Chan, J. W., Taylor, D. & Huser, T. R., Apr 2011, In : Journal of Optics. 13, 4, 044021.

Research output: Contribution to journalArticle

20 Scopus citations

Thrombotic thrombocytopenic purpura in a child with systemic lupus erythematosus

Thampi, S., Salmi, D., Imashuku, S., Ducore, J. M. & Satake, N., Apr 2011, In : Journal of Pediatric Hematology/Oncology. 33, 3, p. 221-223 3 p.

Research output: Contribution to journalArticle

5 Scopus citations
2010

Advancement of pediatric blood and marrow transplantation research in North America: Priorities of the pediatric blood and marrow transplant consortium

Pulsipher, M. A., Horwitz, E. M., Haight, A. E., Kadota, R., Chen, A. R., Frangoul, H., Cooper, L. J. N., Jacobsohn, D. A., Goyal, R. K., Mitchell, D., Nieder, M. L., Yanik, G., Cowan, M. J., Soni, S., Gardner, S., Shenoy, S., Taylor, D., Cairo, M. & Schultz, K. R., Sep 2010, In : Biology of Blood and Marrow Transplantation. 16, 9, p. 1212-1221 10 p.

Research output: Contribution to journalArticle

9 Scopus citations

Comparison of real-time microvascular abnormalities in pediatric and adult sickle cell anemia patients

Cheung, A. T. W., Miller, J. W., Craig, S. M., To, P. L., Lin, X., Samarron, S. L., Chen, P. C. Y., Zwerdling, T., Wun, T., Li, C-S. & Green, R., Nov 2010, In : American Journal of Hematology. 85, 11, p. 899-901 3 p.

Research output: Contribution to journalArticle

23 Scopus citations

Detection of doxorubicin-induced apoptosis of leukemic T-lymphocytes by laser tweezers Raman spectroscopy

Moritz, T. J., Taylor, D. S., Krol, D. M., Fritch, J. & Chan, J. W., Nov 1 2010, In : Biomedical Optics Express. 1, 4, p. 1138-1147 10 p.

Research output: Contribution to journalArticle

44 Scopus citations

Diagnostic challenges in native valve fungal endocarditis producing a massive septic pulmonary embolus

Salmi, D., Bhat, A., Corman, L., Raff, G. W. & Satake, N., 2010, In : Japanese Journal of Medical Mycology. 51, 4, p. 207-210 4 p.

Research output: Contribution to journalArticle

5 Scopus citations

Diagnostic X-rays and risk of childhood leukaemia

Bartley, K., Metayer, C., Selvin, S., Ducore, J. M. & Buffler, P., Dec 2010, In : International Journal of Epidemiology. 39, 6, p. 1628-1637 10 p., dyq162.

Research output: Contribution to journalArticle

68 Scopus citations

Effect of cefazolin treatment on the nonresonant raman signatures of the metabolic state of individual escherichia coli cells

Moritz, T. J., Taylor, D. S., Polage, C. R., Krol, D. M., Lane, S. M. & Chan, J. W., Apr 1 2010, In : Analytical Chemistry. 82, 7, p. 2703-2710 8 p.

Research output: Contribution to journalArticle

52 Scopus citations

Evaluation of Escherichia coli cell response to antibiotic treatment by use of Raman spectroscopy with laser tweezers

Moritz, T. J., Polage, C. R., Taylor, D. S., Krol, D. M., Lane, S. M. & Chan, J. W., Nov 2010, In : Journal of Clinical Microbiology. 48, 11, p. 4287-4290 4 p.

Research output: Contribution to journalArticle

28 Scopus citations

Laser tweezers Raman spectroscopic analysis of single cells and their dynamics

Chan, J. W., Moritz, T. J., Taylor, D. S., Polage, C. R., Krol, D. M. & Lane, S. M., 2010, AIP Conference Proceedings. Vol. 1267. p. 225-226 2 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Neuroblastoma of unknown primary site with periorbital bone metastasis in a child

Salmi, D., Patel, C. V., Imashuku, S., Shimada, H. & Satake, N., Aug 2010, In : Pediatric Blood and Cancer. 55, 2, p. 361-363 3 p.

Research output: Contribution to journalArticle

7 Scopus citations

Novel in vivo model of inducible multi-drug resistance in acute lymphoblastic leukemia with chromosomal translocation t(4;11)

Zunino, S. J., Storms, D. H. & Ducore, J. M., Oct 2010, In : Cancer Letters. 296, 1, p. 49-54 6 p.

Research output: Contribution to journalArticle

5 Scopus citations

Parallel analysis of individual biological cells using multifocal laser tweezers Raman spectroscopy

Liu, R., Taylor, D. S., Matthews, D. L. & Chan, J. W., Nov 2010, In : Applied Spectroscopy. 64, 11, p. 1308-1310 3 p.

Research output: Contribution to journalArticle

23 Scopus citations
8 Scopus citations

STX11 mutations and clinical phenotypes of familial hemophagocytic lymphohistiocytosis in North America

Marsh, R. A., Satake, N., Biroschak, J., Jacobs, T., Johnson, J., Jordan, M. B., Bleesing, J. J., Filipovich, A. H. & Zhang, K., Jul 15 2010, In : Pediatric Blood and Cancer. 55, 1, p. 134-140 7 p.

Research output: Contribution to journalArticle

27 Scopus citations
7 Scopus citations