Research Output

2020

A state-of-the-science review of arsenic’s effects on glucose homeostasis in experimental models

Castriota, F., Rieswijk, L., Dahlberg, S., La Merrill, M. A., Steinmaus, C., Smith, M. T. & Wang, J. C., Jan 2020, In : Environmental health perspectives. 128, 1, 016001.

Research output: Contribution to journalReview article

Open Access

Chronic arsenic exposure impairs adaptive thermogenesis in male C57BL/6J mice

Castriota, F., Zushin, P. J. H., Sanchez, S. S., Phillips, R. V., Hubbard, A., Stahl, A., Smith, M. T., Wang, J. C. & la Merrill, M. A., May 2020, In : American Journal of Physiology - Endocrinology and Metabolism. 318, 5, p. E667-E677

Research output: Contribution to journalArticle

1 Scopus citations

Consensus on the key characteristics of endocrine-disrupting chemicals as a basis for hazard identification

La Merrill, M. A., Vandenberg, L. N., Smith, M. T., Goodson, W., Browne, P., Patisaul, H. B., Guyton, K. Z., Kortenkamp, A., Cogliano, V. J., Woodruff, T. J., Rieswijk, L., Sone, H., Korach, K. S., Gore, A. C., Zeise, L. & Zoeller, R. T., Jan 1 2020, In : Nature Reviews Endocrinology. 16, 1, p. 45-57 13 p.

Research output: Contribution to journalArticle

Open Access
16 Scopus citations

Structure-based discovery of the endocrine disrupting effects of hydraulic fracturing chemicals as novel androgen receptor antagonists

Tachachartvanich, P., Azhagiya Singam, E. R., Durkin, K. A., Smith, M. T. & La Merrill, M. A., Oct 2020, In : Chemosphere. 257, 127178.

Research output: Contribution to journalArticle

2019

Exposure to Persistent Organic Pollutants (POPs) and Their Relationship to Hepatic Fat and Insulin Insensitivity among Asian Indian Immigrants in the United States

La Merrill, M. A., Johnson, C. L., Smith, M. T., Kandula, N. R., Macherone, A., Pennell, K. D. & Kanaya, A. M., Dec 3 2019, In : Environmental Science and Technology. 53, 23, p. 13906-13918 13 p.

Research output: Contribution to journalArticle

3 Scopus citations

In utero exposure to poly− and perfluoroalkyl substances (PFASs) and subsequent breast cancer

Cohn, B. A., La Merrill, M. A., Krigbaum, N. Y., Wang, M., Park, J. S., Petreas, M., Yeh, G., Hovey, R. C., Zimmermann, L. & Cirillo, P. M., Jan 1 2019, (Accepted/In press) In : Reproductive Toxicology.

Research output: Contribution to journalArticle

5 Scopus citations

Metabolome Wide Association Study of serum DDT and DDE in Pregnancy and Early Postpartum

Hu, X., Li, S., Cirillo, P., Krigbaum, N., Tran, V. L., Ishikawa, T., La Merrill, M., Jones, D. P. & Cohn, B., Jan 1 2019, In : Reproductive Toxicology.

Research output: Contribution to journalArticle

6 Scopus citations

Oxidative phosphorylation impairment by DDT and DDE

Elmore, S. E. & La Merrill, M., Jan 1 2019, In : Frontiers in Endocrinology. 10, MAR, 122.

Research output: Contribution to journalReview article

Open Access
3 Scopus citations

Structural Dynamics of Agonist and Antagonist Binding to the Androgen Receptor

Azhagiya Singam, E. R., Tachachartvanich, P., La Merrill, M., Smith, M. T. & Durkin, K. A., Sep 12 2019, In : The journal of physical chemistry. B. 123, 36, p. 7657-7666 10 p.

Research output: Contribution to journalArticle

3 Scopus citations

The tributyltin leads to obesogenic mammary gland abnormalities in adult female rats

da Costa, C. S., Miranda-Alves, L., La Merrill, M., Silva, I. V. & Graceli, J. B., Jun 1 2019, In : Toxicology Letters. 307, p. 59-71 13 p.

Research output: Contribution to journalArticle

1 Scopus citations
2018
1 Scopus citations
7 Scopus citations

Elevated levels of organochlorine pesticides in South Asian immigrants are associated with an increased risk of diabetes

Daniels, S. I., Chambers, J. C., Sanchez, S. S., La Merrill, M. A., Hubbard, A. E., Macherone, A., McMullin, M., Zhang, L., Elliott, P., Smith, M. T. & Kooner, J., Aug 2018, In : Journal of the Endocrine Society. 2, 8, p. 832-841 10 p.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations

Metabolic Syndrome and Associated Diseases: From the Bench to the Clinic

Mendrick, D. L., Diehl, A. M., Topor, L. S., Dietert, R. R., Will, Y., La Merrill, M., Bouret, S., Varma, V., Hastings, K. L., Schug, T. T., Emeigh Hart, S. G. & Burleson, F. G., Mar 1 2018, In : Toxicological sciences : an official journal of the Society of Toxicology. 162, 1, p. 36-42 7 p.

Research output: Contribution to journalReview article

Open Access
23 Scopus citations

Quantitative assessment of cyanide in cystic fibrosis sputum and its oxidative catabolism by hypochlorous acid

Eiserich, J. P., Ott, S. P., Kadir, T., Morrissey, B. M., Hayakawa, K. A., La Merrill, M. A. & Cross, C. E., Dec 1 2018, In : Free Radical Biology and Medicine. 129, p. 146-154 9 p.

Research output: Contribution to journalArticle

The association between p,p″-DDE levels and left ventricular mass is mainly mediated by obesity

La Merrill, M., Lind, P. M., Salihovic, S., van Bavel, B. & Lind, L., Jan 1 2018, In : Environmental Research. 160, p. 541-546 6 p.

Research output: Contribution to journalArticle

1 Scopus citations
2017

2,4-dichlorophenoxyacetic acid (2,4-D) and risk of non-Hodgkin lymphoma: a meta-analysis accounting for exposure levels

Smith, A. M., Smith, M. T., La Merrill, M., Liaw, J. & Steinmaus, C., Apr 1 2017, In : Annals of Epidemiology. 27, 4, p. 281-289.e4

Research output: Contribution to journalReview article

12 Scopus citations

And now for something completely different: Diversity in ligand-dependent activation of Ah receptor responses

Denison, M. S. & Faber, S. C., Feb 1 2017, In : Current Opinion in Toxicology. 2, p. 124-131 8 p.

Research output: Contribution to journalReview article

29 Scopus citations

Assessment of dioxin-like activity in PM10 air samples from an industrial location in Algeria, using the DRE-CALUX bioassay

Khedidji, S., Croes, K., Yassaa, N., Ladji, R., Denison, M. S., Baeyens, W. & Elskens, M., May 1 2017, In : Environmental Science and Pollution Research. 24, 13, p. 11868-11877 10 p.

Research output: Contribution to journalArticle

5 Scopus citations

Association between exposure to p,p′-DDT and its metabolite p,p′-DDE with obesity: Integrated systematic review and meta-analysis

Cano-Sancho, G., Salmon, A. G. & La Merrill, M., Sep 1 2017, In : Environmental Health Perspectives. 125, 9, 096002.

Research output: Contribution to journalReview article

29 Scopus citations

Correction to: Parma consensus statement on metabolic disruptors (Environmental Health: A Global Access Science Source (2015) 14:1 (54) DOI: 10.1186/s12940-015-0042-7)

Heindel, J. J., Vom Saal, F. S., Blumberg, B., Bovolin, P., Calamandrei, G., Ceresini, G., Cohn, B. A., Fabbri, E., Gioiosa, L., Kassotis, C., Legler, J., La Merrill, M., Rizzi, L., Machtinger, R., Mantovani, A., Mendez, M. A., Montanini, L., Molteni, L., Nagel, S. C., Parmigiani, S. & 11 others, Panzica, G., Paterlini, S., Pomatto, V., Ruzzin, J., Sartor, G., Schug, T. T., Street, M. E., Suvorov, A., Volpi, R., Zoeller, R. T. & Palanza, P., Dec 6 2017, In : Environmental Health: A Global Access Science Source. 16, 1, 130.

Research output: Contribution to journalComment/debate

Open Access
1 Scopus citations

Development of a bioanalytical test battery for water quality monitoring: Fingerprinting identified micropollutants and their contribution to effects in surface water

Neale, P. A., Altenburger, R., Aït-Aïssa, S., Brion, F., Busch, W., de Aragão Umbuzeiro, G., Denison, M. S., Du Pasquier, D., Hilscherová, K., Hollert, H., Morales, D. A., Novák, J., Schlichting, R., Seiler, T. B., Serra, H., Shao, Y., Tindall, A. J., Tollefsen, K. E., Williams, T. D. & Escher, B. I., Oct 15 2017, In : Water Research. 123, p. 734-750 17 p.

Research output: Contribution to journalArticle

79 Scopus citations

Do PCDD/PCDF standard solutions used in dioxin analysis pose a risk as potentially acutely toxic to lab personnel?

Malisch, R., Denison, M. S., Fiedler, H., Fürst, P., Hoogenboom, R. L. A. P., Schaechtele, A., Schrenk, D. & van den Berg, M., Oct 1 2017, In : Chemosphere. 185, p. 489-498 10 p.

Research output: Contribution to journalReview article

Down-regulation of cytochrome P450 1A1 by monomethylarsonous acid in human HepG2 cells

Elshenawy, O. H., Abdelhamid, G., Soshilov, A. A., Denison, M. S. & El-Kadi, A. O. S., Mar 15 2017, In : Toxicology Letters. 270, p. 34-50 17 p.

Research output: Contribution to journalArticle

4 Scopus citations

Estrogenic Activity Measurements in Water Using Diffusive Gradients in Thin-Film Coupled with an Estrogen Bioassay

Guo, W., Van Langenhove, K., Denison, M. S., Baeyens, W., Elskens, M. & Gao, Y., Dec 19 2017, In : Analytical Chemistry. 89, 24, p. 13357-13364 8 p.

Research output: Contribution to journalArticle

11 Scopus citations

High throughput in vitro and in vivo screening of inland waters of Southern California

Mehinto, A. C., Vandervort, D. R., Lao, W., He, G., Denison, M. S., Vliet, S. M., Volz, D. C., Mazor, R. D. & Maruya, K. A., Sep 1 2017, In : Environmental Science: Processes and Impacts. 19, 9, p. 1142-1149 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

In Vitro Evaluation of Mitochondrial Function and Estrogen Signaling in Cell Lines Exposed to the Antiseptic Cetylpyridinium Chloride

Datta, S., He, G., Tomilov, A., Sahdeo, S., Denison, M. S. & Cortopassi, G. A., Aug 22 2017, In : Environmental Health Perspectives. 125, 8, 1 p.

Research output: Contribution to journalArticle

10 Scopus citations

Microbial-derived 1,4-Dihydroxy-2-naphthoic acid and related compounds as aryl hydrocarbon receptor agonists/antagonists: Structure-activity relationships and receptor modeling

Cheng, Y., Jin, U. H., Davidson, L. A., Chapkin, R. S., Jayaraman, A., Tamamis, P., Orr, A., Allred, C., Denison, M. S., Soshilov, A., Weaver, E. & Safe, S., Feb 1 2017, In : Toxicological Sciences. 155, 2, p. 458-473 16 p.

Research output: Contribution to journalArticle

15 Scopus citations

Oreochromis mossambicus

Cruz, S. I. R., Phillips, M. A., Kültz, DI. & Rice, R. H., May 1 2017, In : PLoS One. 12, 5, e0177016.

Research output: Contribution to journalArticle

Proteomic analysis of hair shafts from monozygotic twins: Expression profiles and genetically variant peptides

Wu, P. W., Mason, K. E., Durbin-Johnson, B. P., Salemi, M., Phinney, B. S., Rocke, D. M., Parker, G. J. & Rice, R. H., Jul 1 2017, In : Proteomics. 17, 13-14, 1600462.

Research output: Contribution to journalArticle

14 Scopus citations

Proteomic profiling of Pachyonychia congenita plantar callus

Rice, R. H., Durbin-Johnson, B. P., Salemi, M., Schwartz, M. E., Rocke, D. M. & Phinney, B. S., Aug 8 2017, In : Journal of Proteomics. 165, p. 132-137 6 p.

Research output: Contribution to journalArticle

8 Scopus citations

Structural modeling of the AhR: ARNT complex in the bHLH-PASA-PASB region elucidates the key determinants of dimerization

Corrada, D., Denison, M. S. & Bonati, L., 2017, In : Molecular BioSystems. 13, 5, p. 981-990 10 p.

Research output: Contribution to journalArticle

7 Scopus citations

Tgm1-like transglutaminases in tilapia (Oreochromis mossambicus)

Rodriguez Cruz, S. I., Phillips, M. A., Kültz, D. & Rice, R. H., 2017, In : PLoS One. 12, 5, p. e0177016

Research output: Contribution to journalArticle

1 Scopus citations

Triphenyl phosphate enhances adipogenic differentiation, glucose uptake and lipolysis via endocrine and noradrenergic mechanisms

Cano-Sancho, G., Smith, A. & La Merrill, M., Apr 1 2017, In : Toxicology in Vitro. 40, p. 280-288 9 p.

Research output: Contribution to journalArticle

18 Scopus citations

Use of nuclear receptor luciferase-based bioassays to detect endocrine active chemicals in a biosolids-biochar amended soil

Anderson, C. G., Joshi, G., Bair, D. A., Oriol, C., He, G., Parikh, S. J., Denison, M. S. & Scow, K. M., Aug 1 2017, In : Chemosphere. 181, p. 160-167 8 p.

Research output: Contribution to journalArticle

4 Scopus citations
2016

Assessment of estrogenic activity in PM10 air samples with the ERE-CALUX bioassay: Method optimization and implementation at an urban location in Flanders (Belgium)

Croes, K., Debaillie, P., Van den Bril, B., Staelens, J., Vandermarken, T., Van Langenhove, K., Denison, M. S., Leermakers, M. & Elskens, M., Feb 1 2016, In : Chemosphere. 144, p. 392-398 7 p.

Research output: Contribution to journalArticle

3 Scopus citations

Assessment of estrogenic and androgenic activity in PM10 air samples from an urban, industrial and rural area in Flanders (Belgium) using the CALUX bioassay

Croes, K., Van den Heuvel, R., Van den Bril, B., Staelens, J., Denison, M. S., Van Langenhove, K., Vandermarken, T. & Elskens, M., Oct 1 2016, In : Environmental Research. 150, p. 66-72 7 p.

Research output: Contribution to journalArticle

4 Scopus citations

Auto-induction mechanism of aryl hydrocarbon receptor 2 (AHR2) gene by TCDD-activated AHR1 and AHR2 in the red seabream (Pagrus major)

Bak, S. M., Iida, M., Soshilov, A. A., Denison, M. S., Iwata, H. & Kim, E. Y., May 17 2016, (Accepted/In press) In : Archives of Toxicology. p. 1-12 12 p.

Research output: Contribution to journalArticle

3 Scopus citations

Changes in Menidia beryllina Gene Expression and In Vitro Hormone-Receptor Activation After Exposure to Estuarine Waters Near Treated Wastewater Outfalls

Cole, B. J., Brander, S. M., Jeffries, K. M., Hasenbein, S., He, G., Denison, M. S., Fangue, N. A. & Connon, R. E., Aug 1 2016, In : Archives of Environmental Contamination and Toxicology. 71, 2, p. 210-223 14 p.

Research output: Contribution to journalArticle

9 Scopus citations

Characterisation and implementation of the ERE-CALUX bioassay on indoor dust samples of kindergartens to assess estrogenic potencies

Vandermarken, T., De Galan, S., Croes, K., Van Langenhove, K., Vercammen, J., Sanctorum, H., Denison, M. S., Goeyens, L., Elskens, M. & Baeyens, W., Jan 1 2016, In : Journal of Steroid Biochemistry and Molecular Biology. 155, p. 182-189 8 p.

Research output: Contribution to journalArticle

12 Scopus citations

Deciphering Dimerization Modes of PAS Domains: Computational and Experimental Analyses of the AhR:ARNT Complex Reveal New Insights Into the Mechanisms of AhR Transformation

Corrada, D., Soshilov, A. A., Denison, M. S. & Bonati, L., Jun 1 2016, In : PLoS Computational Biology. 12, 6, e1004981.

Research output: Contribution to journalArticle

11 Scopus citations

Demonstration of protein-based human identification using the hair shaft proteome

Parker, G. J., Leppert, T., Anex, D. S., Hilmer, J. K., Matsunami, N., Baird, L., Stevens, J., Parsawar, K., Durbin-Johnson, B. P., Rocke, D. M., Nelson, C., Fairbanks, D. J., Wilson, A. S., Rice, R. H., Woodward, S. R., Bothner, B., Hart, B. R. & Leppert, M., Sep 1 2016, In : PLoS One. 11, 9, e0160653.

Research output: Contribution to journalArticle

46 Scopus citations

Development of an integrated approach for comparison of in vitro and in vivo responses to particulate matter

Breznan, D., Karthikeyan, S., Phaneuf, M., Kumarathasan, P., Cakmak, S., Denison, M. S., Brook, J. R. & Vincent, R., 2016, In : Particle and Fibre Toxicology. 13, 1, 41.

Research output: Contribution to journalArticle

10 Scopus citations

Development of a recombinant human ovarian (BG1) cell line containing estrogen receptor α and β for improved detection of estrogenic/antiestrogenic chemicals

Brennan, J. C., Bassal, A., He, G. & Denison, M. S., Jan 1 2016, In : Environmental Toxicology and Chemistry. 35, 1, p. 91-100 10 p.

Research output: Contribution to journalArticle

10 Scopus citations

Effect of benzene and ethylbenzene on the transcription of methyl-tert-butyl ether degradation genes of Methylibium petroleiphilum PM1

Joshi, G., Schmidt, R., Scow, K. M., Denison, M. S. & Hristova, K. R., Sep 1 2016, In : Microbiology (United Kingdom). 162, 9, p. 1563-1571 9 p.

Research output: Contribution to journalArticle

5 Scopus citations

Effects of neonicotinoids on promoter-specific expression and activity of aromatase (CYP19) in human adrenocortical carcinoma (H295R) and primary umbilical vein endothelial (HUVEC) cells

Caron-Beaudoin, É., Denison, M. S. & Sanderson, J. T., Jan 1 2016, In : Toxicological Sciences. 149, 1, p. 134-144 11 p., kfv220.

Research output: Contribution to journalArticle

24 Scopus citations

Lce1 Family Members Are Nrf2-Target Genes that Are Induced to Compensate for the Loss of Loricrin

Ishitsuka, Y., Huebner, A. J., Rice, R. H., Koch, P. J., Speransky, V. V., Steven, A. C. & Roop, D. R., Aug 1 2016, In : Journal of Investigative Dermatology. 136, 8, p. 1656-1663 8 p.

Research output: Contribution to journalArticle

13 Scopus citations

Parallel responses of human epidermal keratinocytes to inorganic SbIII and AsIII

Phillips, M. A., Cánovas, A., Wu, P. W., Islas-Trejo, A., Medrano, J. F. & Rice, R. H., 2016, In : Environmental Chemistry. 13, 6, p. 963-970 8 p.

Research output: Contribution to journalArticle

8 Scopus citations

Perinatal DDT exposure induces hypertension and cardiac hypertrophy in adult mice

La Merrill, M., Sethi, S., Benard, L., Moshier, E., Haraldsson, B. & Buettner, C., Nov 1 2016, In : Environmental Health Perspectives. 124, 11, p. 1722-1727 6 p.

Research output: Contribution to journalArticle

5 Scopus citations

Perinatal triphenyl phosphate exposure accelerates type 2 diabetes onset and increases adipose accumulation in UCD-type 2 diabetes mellitus rats

Green, A. J., Graham, J. L., Gonzalez, E. A., La Frano, M. R., Petropoulou, S. S. E., Park, J. S., Newman, J. W., Stanhope, K., Havel, P. J. & La Merrill, M., Apr 13 2016, (Accepted/In press) In : Reproductive Toxicology.

Research output: Contribution to journalArticle

16 Scopus citations